Financial Instability and Credit Constraint: Evidence from the Cost of Bank Financing

This paper examines the relation between the degree of firms’ financial constraint and the observed rise in the cost of bank financing during the global financial crisis of 2008. It introduces a new measure of financial constraint: the lending rate paid by each firm on working capital loans. In line with previous research, the findings point to a more severe contraction in credit supply for more credit constrained firms. Additionally, the results show that the existence of collateral and a large portfolio of lenders mitigate the credit supply contraction observed in that period.

Learning to Rank Academic Experts in the DBLP Dataset

Expert finding is an information retrieval task that is concerned with the search for the most knowledgeable people with respect to a specific topic, and the search is based on documents that describe people's activities. The task involves taking a user query as input and returning a list of people who are sorted by their level of expertise with respect to the user query. Despite recent interest in the area, the current state-of-the-art techniques lack in principled approaches for optimally combining different sources of evidence. This article proposes two frameworks for combining multiple estimators of expertise. These estimators are derived from textual contents, from graph-structure of the citation patterns for the community of experts, and from profile information about the experts. More specifically, this article explores the use of supervised learning to rank methods, as well as rank aggregation approaches, for combing all of the estimators of expertise. Several supervised learning algorithms, which are representative of the pointwise, pairwise and listwise approaches, were tested, and various state-of-the-art data fusion techniques were also explored for the rank aggregation framework. Experiments that were performed on a dataset of academic publications from the Computer Science domain attest the adequacy of the proposed approaches.Comment: Expert Systems, 2013. arXiv admin note: text overlap with arXiv:1302.041

Ultrasensitivity in phosphorylation-dephosphorylation cycles with little substrate

Cellular decision-making is driven by dynamic behaviours, such as the preparations for sunrise enabled by circadian rhythms and the choice of cell fates enabled by positive feedback. Such behaviours are often built upon ultrasensitive responses where a linear change in input generates a sigmoidal change in output. Phosphorylation-dephosphorylation cycles are one means to generate ultrasensitivity. Using bioinformatics, we show that in vivo levels of kinases and phosphatases frequently exceed the levels of their corresponding substrates in budding yeast. This result is in contrast to the conditions often required by zero-order ultrasensitivity, perhaps the most well known means for how such cycles become ultrasensitive. We therefore introduce a mechanism to generate ultrasensitivity when numbers of enzymes are higher than numbers of substrates. Our model combines distributive and non-distributive actions of the enzymes with two-stage binding and concerted allosteric transitions of the substrate. We use analytical and numerical methods to calculate the Hill number of the response. For a substrate with [Formula: see text] phosphosites, we find an upper bound of the Hill number of [Formula: see text], and so even systems with a single phosphosite can be ultrasensitive. Two-stage binding, where an enzyme must first bind to a binding site on the substrate before it can access the substrate's phosphosites, allows the enzymes to sequester the substrate. Such sequestration combined with competition for each phosphosite provides an intuitive explanation for the sigmoidal shifts in levels of phosphorylated substrate. Additionally, we find cases for which the response is not monotonic, but shows instead a peak at intermediate levels of input. Given its generality, we expect the mechanism described by our model to often underlay decision-making circuits in eukaryotic cells

A geo-temporal information extraction service for processing descriptive metadata in digital libraries

In the context of digital map libraries, resources are usually described according to metadata records that define the relevant subject, location, time-span, format and keywords. On what concerns locations and time-spans, metadata records are often incomplete or they provide information in a way that is not machine-understandable (e.g. textual descriptions). This paper presents techniques for extracting geotemporal information from text, using relatively simple text mining methods that leverage on a Web gazetteer service. The idea is to go from human-made geotemporal referencing (i.e. using place and period names in textual expressions) into geo-spatial coordinates and time-spans. A prototype system, implementing the proposed methods, is described in detail. Experimental results demonstrate the efficiency and accuracy of the proposed approaches

The DIGMAP geo-temporal web gazetteer service

This paper presents the DIGMAP geo-temporal Web gazetteer service, a system providing access to names of places, historical periods, and associated geo-temporal information. Within the DIGMAP project, this gazetteer serves as the unified repository of geographic and temporal information, assisting in the recognition and disambiguation of geo-temporal expressions over text, as well as in resource searching and indexing. We describe the data integration methodology, the handling of temporal information and some of the applications that use the gazetteer. Initial evaluation results show that the proposed system can adequately support several tasks related to geo-temporal information extraction and retrieval