21 research outputs found

    Comparing body composition between the sweet-liking phenotypes: experimental data, systematic review and individual participant data meta-analysis

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    Legislation aimed at reducing sugar intake assumes that sweet-liking drives overconsumption. However, evidence that greater liking for sweet taste is associated with unhealthier body size is mixed and complicated by relatively small samples, an overreliance on body mass index (BMI) and lack of classification using sweet-liking phenotypes. We aimed to address these issues by examining body size data in two larger samples with sweet-liking phenotyping: extreme sweet-likers (ESL), moderate sweet-likers (MSL) and sweet-dislikers (SD). Adults (18-34yrs), attended a two-session lab-based experiment involving phenotyping for sweet-liking status and a bioelectrical impedance body composition measurement (Experiment One: N=200; Experiment Two: N=314). A significant effect of sweet-liking phenotype on fat-free mass (FFM) was found in both experiments, with ESL having significantly higher FFM than SD. In Experiment One, SD had a significantly higher body fat percentage (BF%) than ESL and MSL. However, as these data are from one research group in a young, predominantly westernised population, and the results did not perfectly replicate, we conducted an individual participant data (IPD) meta-analysis. Systematic searches across four databases identified 5736 potential articles. Of these, 53 papers met our search criteria: a taste assessment that measured liking using sucrose (>13.7% w/v), which allowed sweet-liking phenotyping and included either BMI, BF%, FFM or waist-circumference. A robust one-stage IPD meta-analysis of 15 studies controlling for sex revealed no significant differences in BF% (n = 1836) or waist-circumference (n = 706). For BMI (n = 2368), MSL had slightly lower BMI than ESL, who had the highest overall BMI. Most interestingly, for FFM (n = 768), MSL and SD showed significantly lower FFM than ESL. This suggests that the higher BMI often seen in sweet-likers may be due to a larger FFM and questions the simple model where sweet liking alone is a risk factor for obesity.</p
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