Additional file 1: of Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing

Figure S1. Scanning electron microscopy (SEM) images of cord cross-section. SEM images show two zones. Zone 1 displays a section in between the umbilical vein and two arteries, and zone 2 displays a region closer to the umbilical vein. (A–E) Magnification of zone 1. (F–J) Magnification of zone 2. (TIF 10880 kb

Additional file 3: of Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing

Video S1. Time-lapse imaging showing that exosomes concentrate to the cell periphery and, by 3 h, disappear as depicted by a decrease in red fluorescence. (WMV 32791 kb

Additional file 4: of Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing

Figure S3. Cell viability quantification for keratinocytes. Control medium-treated keratinocytes compared with exosome-treated and α2M (100 ng/ml)-treated keratinocytes. *p < 0.05, ***p < 0.001. N = 6 for control and exosomes; N = 12 for α2M. (TIF 4635 kb

Additional file 2: of Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing

Figure S2. Schematic representation of the exosome isolation protocol. (TIF 3668 kb

Additional file 1: of The response of muscle progenitor cells to cutaneous thermal injury

Immunohistochemistry of F4/80-positive cells in muscle following thermal injury. Representative immunohistochemistry images showing F4/80 staining in sham, 2 days, 7 days, and 14 days post-burn in gastrocnemius muscle. Images were obtained at 20× magnification. (TIF 40911 kb