Miranda Fricker's Epistemic Injustice: An Attempt at Appropriation of Philippine Social Realities

Miranda Fricker argues of an injustice that is distinctly epistemic though it was born out of societal discrimination, identity power, and racial prejudice. More so, Fricker attempts to establish a theoretical space, where ethics, epistemology, and socio-politics can converge. An epistemology which concerns knowledge not for knowledge's sake alone, but the kind of knowledge that can morally awaken a knowing subject and which can hopefully influence or bring forth a collective social and political change

Enrique Dussel's Philosophy of Liberation: Philosophical Reflections at the Time of the COVID-19 Global Pandemic

The COVID-19 pandemic began in Wuhan, China sometime in November 2019. The virus has spread sporadically across countries and continents wreaking havoc medically, politically, and individually as it claimed more than three hundred thousand lives and had virally infected more than four million of the global population. This phenomenon has led us to confront inevitable eschatological questions: Is this a sign of the end times? Will this efface the vulnerable human race? Will this disrupt the global economy as capitalism had collapsed worldwide? Do these events signal a new political era, perhaps the dawn of socialism and communism as countries worldwide are led to confront its own deficiencies and inadequacies? Which social and political systems and worldviews are efficient particularly in this age of globalization? What are our chances for human survival

Critical Discourses on Technology in the Era of the Anthropocene

This paper attempts to unravel and explore the stark contradiction between the quest for technological advancement and the struggle for human welfare and well-being. In the frame of Hegel’s master and slave dialectic, the author tries to present the notions of humanity and technology as thesis and antitheses by which the dawning synthesis of technological sensitivity to nature and an ecologically friendly human innovation and emancipation can be made possible. The paper draws heavily from the concepts introduced by notable philosophers, such as, Bernard Stiegler, Donna Haraway, N. Katherine Hayes, Andrew Feenberg, Douglas Kellner, Herbert Marcuse, George Lukacs, Georg Friedrich Wilhelm Hegel, Karl Marx, Martin Heidegger, Karl Popper, Aldo Leopold, and Enrique Dussel. Out from the brilliant concepts of these thinkers, altogether their ideas had served as the building blocks in tracing the origin, nature, history, development, and the future of both the humankind and technology, and its impact to the natural ecology. The author attempts to work out a coherent synthesis of these prevailing thinkers. Their ideas aimed to lead, support, enhance, or give way to the possibility of the notion of an ecologically, environmentally, nature and human-friendly technology

Immunopathology of Leishmaniasis: an update.

Leishmaniasis represents a severe, increasing, public health problem. The perspective of its control is highly dependent on research progress, on therapeutic manipulations of the immune system, and on vaccine development. There is a correlation between the clinical outcome of Leishmania infection and the cytokine response profile. While a protective immune response against Leishmania has been clearly identified to be related to the influence of a type-1 response and IFN-gamma production, the precise role of T helper (TH) 2 cytokines in non-healing infections requires further exploration. IL-4 and IL-13 (TH2 cytokines) can promote disease progression in cutaneous leishmaniasis, whereas IL-4 would appear to enhance protective type-1 responses in visceral leishmaniasis. Thus, the TH1/TH2 paradigm of resistance/susceptibility to intracellular parasites is probably an oversimplification of a more complicated network of regulatory/counter regulatory interactions. Moreover, the presence of antigen specific regulatory T cell subsets may provide an environment that contributes to the balance between TH1 and TH2 cells. Finally, the involvement of CD8 positive T cells has been described, but the modality of their function in this kind of infection has not been so far elucidated

Reply

We thank Volta et al for their interest in our work1 and for their comments and data on the frequency of autoimmune diseases and serum autoantibodies in patients suffering from nonceliac wheat sensitivity (NCWS). These authoritative colleagues have emphasized that celiac disease is a well-established autoimmune condition, and we agree that NCWS is still an undefined syndrome with uncertain pathogenesis

Waterhouse Friderichsen Syndrome: Medico-legal issues

The Waterhouse-Friderichsen Syndrome (WFS) is a pediatric emergency characterized by high mortality due to the combination of bilateral adrenal haemorrhage, meningococcal infection and cutaneous purpura. WFS often raises medico-legal problems related to missed or delayed diagnosis mainly related to the short clinical course, the sudden onset of symptoms and unexpected death. We report the death of a 2-year-old child who had no other pathologies. Death occurred quickly about 20 h after the first care visit. The forensic autopsy was ordered following the parental complaint for diagnostic delay in primary care. Clinical data, autopsy and histological findings were consistent for WFS by Neisseria meningitidis (NM) serotype B. Medical malpractice was excluded. WFS has a rapid clinical course. By the time fever and purpura are reported, it may be too late as thrombotic and bleeding complications may already be present

Infections are a very dangerous affair: Enterobiasis and death

Background: Enterobiasis or oxyuriasis from Enterobius vermicularis is an infection usually localized in the large bowel and cecum. Generally, the symptoms are characterized by anal itching, and intestinal or nervous disorders. Rarely, it is responsible for death. Methods: A forensic autopsy of a 52-year-old white male inmate who died 5 days after hospitalization was performed. Histological and toxicological analyses were also performed. Results: The death occurred by localization of Enterobius vermicularis in the duodenum and in the proximal ileum, with intestinal haemorrhage, inflammation, and peritonitis documented by histological examination. Conclusion: This is a common infectious disease, and can rarely occur with a fatal outcome, even in advanced populations. The lack of knowledge related to the rarity of death from enterobiasis disease can determine a dangerous concern