Development of fuels and structural materials for fast breeder reactors

Fast breeder reactors (FBRs) are destined to play a crucial role in the Indian nuclear power programme in the foreseeable future. FBR technology involves a multi-disciplinary approach to solve the various challenges in the areas of fuel and materials development. Fuels for FBRs have significantly higher concentration of fissile material than in thermal reactors, with a matching increase in burn-up. The design of the fuel is an important aspect which has to be optimised for efficient, economic and safe production of power. FBR components operate under hostile and demanding environment of high neutron flux, liquid sodium coolant and elevated temperatures. Resistance to void swelling, irradiation creep, and irradiation embrittlement are therefore major considerations in the choice of materials for the core components. Structural and steam generator materials should have good resistance to creep, low cycle fatigue, creep-fatigue interaction and sodium corrosion. The development of carbide fuel and structural materials for the Fast Breeder Test Reactor at Kalpakkam was a great technological challenge. At the Indira Gandhi Centre for Atomic Research (IGCAR), advanced research facilities have been established, and extensive studies have been carried out in the areas of fuel and materials development. This has laid the foundation for the design and development of a 500 MWe Prototype Fast Breeder Reactor. Highlights of some of these studies are discussed in this paper in the context of our mission to develop and deploy FBR technology for the energy security of India in the 21st century

Environmental Performance of the Stormpav Permeable Pavement Using the Stormwater Management Model (SWMM)

Urban stormwater runoff is contaminated with a variety of pollutants, including total suspended solids (TSS) and total phosphorus (TP), as a result of non-source pollution from transportation, residences, and businesses, as well as sediment from human activities and construction sites. These pollutants are expected to degrade the water quality in local rivers and streams, impairing the quality of marine life and contaminating drinking water supplies. This study evaluates the environmental performance of a permeable pavement system in an urban catchment using the stormwater management model (SWMM). Two pavement systems with different hydraulic designs were compared to reduce runoff, increment of groundwater storage and the environmental parameters assessments on total suspended solids (TSS) and Total Phosphorus (TP). The first system comprises a StormPav, which is the UNIMAS innovated green pavement with subsurface hollow cylindrical micro-detention pond storage of about 70% void content. The second system consists of porous concrete (PC) pavement assembled in a layered of coarse and fine particles to ensure water can infiltrate through, with about 40% void content. The environmental impact assessment was applied at Padungan Commercial Centre in the Kuching City of Malaysia. The case study simulated  low impact development (LID) sub-catchment in SWMM to obtain the runoff, infiltration and environmental quality performance. In the assessment, it was found that, for both pavement systems, higher storms at shorter duration resulted in higher reduction efficiency. The StormPav is more effective in reducing runoff while presenting a lower value for environmental assessments in removing TSS and TP compared to PC

Environmental Performance of the Stormpav Permeable Pavement Using the Stormwater Management Model (SWMM)

Urban stormwater runoff is contaminated with a variety of pollutants, including total suspended solids (TSS) and total phosphorus (TP), as a result of non-source pollution from transportation, residences, and businesses, as well as sediment from human activities and construction sites. These pollutants are expected to degrade the water quality in local rivers and streams, impairing the quality of marine life and contaminating drinking water supplies. This study evaluates the environmental performance of a permeable pavement system in an urban catchment using the stormwater management model (SWMM). Two pavement systems with different hydraulic designs were compared to reduce runoff, increment of groundwater storage and the environmental parameters assessments on total suspended solids (TSS) and Total Phosphorus (TP). The first system comprises a StormPav, which is the UNIMAS innovated green pavement with subsurface hollow cylindrical micro-detention pond storage of about 70% void content. The second system consists of porous concrete (PC) pavement assembled in a layered of coarse and fine particles to ensure water can infiltrate through, with about 40% void content. The environmental impact assessment was applied at Padungan Commercial Centre in the Kuching City of Malaysia. The case study simulated  low impact development (LID) sub-catchment in SWMM to obtain the runoff, infiltration and environmental quality performance. In the assessment, it was found that, for both pavement systems, higher storms at shorter duration resulted in higher reduction efficiency. The StormPav is more effective in reducing runoff while presenting a lower value for environmental assessments in removing TSS and TP compared to PC

Complementing chronic frailty assessment at hospital admission with an electronic frailty index (FI-Laboratory) comprising routine blood test results

BACKGROUND: Acutely ill and frail older adults have complex social and health care needs. It is important to understand how this complexity affects acute outcomes for admission to hospital. We validated a frailty index using routine admission laboratory tests with outcomes after patients were admitted to hospital. METHODS: In a prospective cohort of older adults admitted to a large tertiary hospital in the United Kingdom, we created a frailty index from routine admission laboratory investigations (FI-Laboratory) linked to data comprising hospital outcomes. We evaluated the association between the FI-Laboratory and total days spent in hospital, discharge to a higher level of care, readmission and mortality. RESULTS: Of 2552 admissions among 1750 older adults, we were able to generate FI-Laboratory values for 2254 admissions (88.3% of the cohort). More than half of admitted patients were women (55.3%) and the mean age was 84.6 (SD 14.0) years. We found that the FI-Laboratory correlated weakly with the Clinical Frailty Scale (CFS; r2 = 0.09). An increase in the CFS and the equivalent of 3 additional abnormal laboratory test results in the FI-Laboratory, respectively, were associated with an increased proportion of inpatient days (rate ratios [RRs] 1.43, 95% confidence interval [CI] 1.35-1.52; and 1.47, 95% CI 1.41-1.54), discharge to a higher level of care (odd ratios [ORs] 1.39, 95% CI 1.27-1.52; and 1.30, 95% CI 1.16-1.47) and increased readmission rate (hazard ratios [HRs] 1.26, 95% CI 1.17-1.37; and 1.18, 95% CI 1.11-1.26). Increases in the CFS and FI-Laboratory were associated with increased mortality HRs of 1.39 (95% CI 1.28-1.51) and 1.45 (95% CI 1.37-1.54), respectively. INTERPRETATION: We determined that FI-Laboratory, distinct from baseline frailty, could be used to predict risk of many adverse outcomes. The score is therefore a useful way to quantify the degree of acute illness in frail older adults

Mercury: Recovering forgotten passwords using personal devices

Instead of allowing the recovery of original passwords, forgotten passwords are often reset using online mechanisms such as password verification questions (PVQ methods) and password reset links in email. These mechanisms are generally weak, exploitable, and force users to choose new passwords. Emailing the original password exposes the password to third parties. To address these issues, and to allow forgotten passwords to be securely restored, we present a scheme called Mercury. Its primary mode employs user-level public keys and a personal mobile device (PMD) such as a smart-phone, netbook, or tablet. A user generates a key pair on her PMD; the private key remains on the PMD and the public key is shared with different sites (e.g., during account setup). For password recovery, the site sends the (public key)-encrypted password to the user's pre-registered email address, or displays the encrypted password on a webpage, e.g., as a barcode. The encrypted password is then decrypted using the PMD and revealed to the user. A prototype implementation of Mercury is available as an Android application

Clinical features, investigations, and outcomes of pediatric limbic encephalitis: A multicenter study

OBJECTIVES: To describe the clinical presentation, investigations, management, and disease course in pediatric autoimmune limbic encephalitis (LE). METHODS: In this retrospective observational study, from the UK Childhood Neuroinflammatory Disease network, we identified children from six tertiary centers with LE <18 years old between 2008 and 2021. Clinical and paraclinical data were retrieved from medical records. RESULTS: Twenty-five children fulfilling LE criteria were identified, with median age of 11 years (IQR 8, 14) and median follow-up of 24 months (IQR 18, 48). All children presented with seizures; 15/25 (60%) were admitted to intensive care. Neuroimaging demonstrated asymmetric mesial temporal changes in 8/25 (32%), and extra-limbic changes with claustrum involvement in 9/25 (38%). None were positive for LGI1/CASPR2 antibodies (Abs), 2/25 were positive for serum anti-NMDAR Abs, and 2/15 positive for anti-Hu Abs; one died from relapsing neuroblastoma. Two children had serum and CSF anti-GAD antibodies. Initial immune therapy included steroids in 23/25 (92%), intravenous immunoglobulin (IVIg) in 14/25 (56%), and plasma exchange in 7/25 (28%). The commonest second-line treatment was rituximab in 15/25 (60%). Median duration of hospital admission was 21 days (IQR 11, 30). At last follow-up, 13/25 (52%) had refractory seizures and 16/25 (64%) had memory impairment. Six children (24%) had modified Rankin Scale (mRS) scores ≥3. There was no significant difference in mRS, or long-term cognitive and epilepsy outcomes in those who received rituximab versus those who did not. INTERPRETATION: A diagnosis of autoimmune LE was associated with significant morbidity and adverse outcomes in this pediatric cohort