59 research outputs found

    The multiple faces of self-assembled lipidic systems

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    Lipids, the building blocks of cells, common to every living organisms, have the propensity to self-assemble into well-defined structures over short and long-range spatial scales. The driving forces have their roots mainly in the hydrophobic effect and electrostatic interactions. Membranes in lamellar phase are ubiquitous in cellular compartments and can phase-separate upon mixing lipids in different liquid-crystalline states. Hexagonal phases and especially cubic phases can be synthesized and observed in vivo as well. Membrane often closes up into a vesicle whose shape is determined by the interplay of curvature, area difference elasticity and line tension energies, and can adopt the form of a sphere, a tube, a prolate, a starfish and many more. Complexes made of lipids and polyelectrolytes or inorganic materials exhibit a rich diversity of structural morphologies due to additional interactions which become increasingly hard to track without the aid of suitable computer models. From the plasma membrane of archaebacteria to gene delivery, self-assembled lipidic systems have left their mark in cell biology and nanobiotechnology; however, the underlying physics is yet to be fully unraveled

    An experience of developing mission critical software for BIRD attitude control using UML

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    The cry for quality and software release schedules are nightmares for the software engineers. The unification of last decade techniques in the Unified Modeling Language (UML) give a rise for stable platform for software modelling. We show how the UML fit the software engineering process and report the experience made with UML during the development of the BIRD attitude control system

    Bestimmung eines Lastprofils auf vernetzten Arbeitsplatzrechnern

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    To compare new developments in the field of computer performance, it is necessary to simulate a computer system. The simulation of computer system need a representative artificial test workload, which describe the workload of a real computer system. This paper includes a derivation from the real workload to an artificial test workload and concludes with some hypothetical clauses, which came in mind during the measurement. This clauses may be a basis of workload prognosis. (orig.)Available from TIB Hannover: RO 8347(1996,25)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman
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