Senior Recital: Nathan Autry tenor

Kennesaw State University School of Music presents Senior Recital: Nathan Autry, tenor.https://digitalcommons.kennesaw.edu/musicprograms/1718/thumbnail.jp

Senior Recital: Donald Brainerd, bass baritone

Kennesaw State University School of Music presents Senior Recital: Donald Brainerd, bass baritone.https://digitalcommons.kennesaw.edu/musicprograms/1722/thumbnail.jp

Senior Recital: Kharis Belgrave, mezzo soprano

Kennesaw State University School of Music presents Senior Recital: Kharis Belgrave, mezzo soprano.https://digitalcommons.kennesaw.edu/musicprograms/1719/thumbnail.jp

Senior Recital: Lauren Heidinsfelder, mezzo-soprano

Kennesaw State University School of Music presents Senior Recital: Lauren Heidinsfelder, mezzo-soprano. This recital is presented in partial fulfillment of the requirements for the degree Bachelor of Music in Music Education.https://digitalcommons.kennesaw.edu/musicprograms/1755/thumbnail.jp

Senior Recital: Marielle Engels, soprano

Kennesaw State University School of Music presents Senior Recital: Marielle Engels, soprano.https://digitalcommons.kennesaw.edu/musicprograms/1730/thumbnail.jp

APPLICATION OF IMAGE-BASED HIGH CONTENT ANALYSIS FOR THE SCREENING OF BIOACTIVE NATURAL PRODUCTS

Each bioactive compound induces phenotypic changes in target cells that can be made visible by labelling selected molecules of the cells with fluorescent dyes and/or directly observed under the high-throughput microscope. A comparison of the cellular phenotype induced by a compound of interest with known cellular targets allows predicting its mode of action. Over the past 15 years, high-throughput microscopy has been one of the fastest growing fields in cell biology. When combined with automated multiparametric image and data analysis, it is referred to as high-content screening (HCS). Whilst HCS has been successfully applied to the bioactivity characterization of natural products, recent studies used automated microscopy and software to increase speed and to reduce subjective interpretation. In 2017, Institute of Natural Products Chemistry (INPC-VAST) has been equipped with a HCS platform (Olympus Scan^R) that designed for fully automated image acquisition and analysis of biological samples to visually inspect the cellular morphology induced by hit compounds as well as to discriminate from false positives. Accordingly, this short review covers the concepts of HCS and its application in screening of biologically active natural products whose molecular targets could be identified through such approaches

Senior Recital: Trishla Wooten, soprano

Kennesaw State University School of Music presents Senior Recital: Trishla Wooten, soprano. This recital and these program notes are presented in partial fulfillment of the requirements for the degree Bachelor of Music in Performance.https://digitalcommons.kennesaw.edu/musicprograms/1704/thumbnail.jp

First report of Longidorus mindanaoensis Coomans, De Ley, Jimenez and De Ley, 2012 (Nematoda: Longidoridae) from a mangrove forest in Vietnam

Longidorus mindanaoensis was recovered from a mangrove forest in Vietnam. The recovered population is in general morphological agreement with the type population, and the characters of pharyngeal bulb, i.e. the same unique pattern of pharyngeal glands nuclei as well as the lip region morphology, amphidial fovea shape and size and position of vulva corroborated its identity. Molecular studies of the recovered population using D2-D3 expansion segments of large subunit ribosomal DNA (LSU rDNA D2-D3) revealed the D2-D3 sequence of the recovered population is 99.6% similar to the sequence of the type population. A new morphometric range for body size was recorded for the species based upon present Vietnamese population, and the present study emphasized that the diversity of Longidorus spp. in Vietnam could be higher than previously assumed