Amelatonic nodular melanoma

Se informa el caso de una mujer de 36 años de edad con tumor nodular en lóbulo de oreja de dos años de evolución, el cual clínicamente simulaba ser un queloide o un tumor benigno. Al estudio histopatológico se diagnosticó melanoma nodular amelanótico con diferenciación neuroendocrina.[Uribe CJ, Ávila MY, Zárate M, Rueda DF. Melanoma medular amelanótico. MEDUNAB 2002; 5(14):133-135]The case of a 36-year-old woman with a nodular tumor in the earlobe of two years of evolution is reported, which clinically simulated being a keloid or a benign tumor. The histopathological study diagnosed amelanotic nodular melanoma with neuroendocrine differentiation.[Uribe CJ, Ávila MY, Zárate M, Rueda DF. Amelanotic medullary melanoma. MEDUNAB 2002; 5(14):133-135

Circumscribed angiokeratoma. Report of a case and review of the literature

El angioqueratoma circunscrito es el más raro de los angioqueratomas. Aparece desde el nacimiento en las primeras dos décadas de la vida y es más común en mujeres. Generalmente está localizado en piernas y sólo un 10% en miembros superiores, es asintomático. Existen diferencias de opinión encuanto si es una neoplasia o solamente una dilatación de vasos sanguíneos ya existentes. El tratamiento depende del tamaño, profundidad y extensión de la lesión. Se debe considerar la extirpación quirúrgica en la medida en que sea posible. Se describe el caso de un niño de 10 años con cuadro clínico de angioqueratoma circunscrito tratado con crioterapia, con respuesta parcial de las lesiones.[Ávila M, Vásquez AJ, Pierard GE, Arrese JE, Uribe CJ. Angioqueratoma circunscrito. Informe de uncaso y revisión de la literaturaCircumscribed angiokeratoma is the rarest of the angiokeratomas. It appears from birth or in the first two decades of life and is more common in women. It is generally located in the legs and only 10% in the upper limbs, it is asymptomatic. There are differences of opinion as to whether it is a neoplasm or just a dilatation of existing blood vessels. Treatment depends on the size, depth, and extent of the lesion. Surgical removal should be considered whenever possible. The case of a 10-year-old boy with a clinical picture of circumscribed angiokeratoma treated with cryotherapy, with partial response of the lesions, is described. [Ávila M, Vásquez AJ, Pierard GE, Arrese JE, Uribe CJ. Circumscribed angiokeratoma. Report of a case and review of the literatur

Herpetiform dermatitis

Herpetiform dermatitis is an autoimmuneampollae disease characterized by an pruriginouspapulovesicular eruption associated with IgA granulardermical papillayr deposites which are detected by DIF. Thisskin disease has relation to non symptomatical glutensensible intestinal illness. Microscopical examination showmicroabscess with many neutrophilous, eosonophilous in dermis papille and lymphocyte T, neutrophilous,eosinophilous infiltration. Disease pathogenesis is not knownand is considered type IgA complex illness. The effectivetreatment is done with dapsone and a free gluten diet