Building a document genre corpus: a profile of the KRYS I corpus

This paper describes the KRYS I corpus, consisting of documents classified into 70 genre classes. It has been constructed as part of an effort to automate document genre classification as distinct from topic detection. Previously there has been very little work on building corpora of texts which have been classified using a nontopical genre palette. The reason for this is partly due to the fact that genre as a concept, is rooted in philosophy, rhetoric and literature, and highly complex and domain dependent in its interpretation ([11]). The usefulness of genre in everyday information search is only now starting to be recognised and there is no genre classification schema that has been consolidated to have applicable value in this direction. By presenting here our experiences in constructing the KRYS I corpus, we hope to shed light on the information gathering and seeking behaviour and the role of genre in these activities, as well as a way forward for creating a better corpus for testing automated genre classification tasks and the application of these tasks to other domains.

Development Needs of Middle Managers In Higher Education Institutions: A Case Study of A Post 1992 New University in UK

Development of staff by Human Resources (HR) department in any organisation is crucial to implement its strategy, operations, goals and for eventual success. Similarly, in Higher Education Institutions (HEIs) the Middle Managers (MM) are drivers who execute organisation vision, mission and contribute towards its desired attainment. MM job titles at faculty level include Deans, Head of Departments, Subject leaders and Principle lecturers/Programme leaders. However, evidenced from contemporary literature, changes and challenges transpiring in HEIs sector is influencing and generating tremendous pressures and workloads for MM to work effectively and efficiently in their respective roles. Therefore, the fortitude of this study is to explore this phenomenon and capture true MM Development Needs (DN) and propose a conceptual model. In stage one (qualitative stage), a semi structured interview protocol was derived from 2 pilot semi structured interviews and literature review theoretical model. A meso case study (sub cases and individual embedded cases) of a UK Post 1992 university was conducted with 23 semi-structured interviews lasting an hour each. 14 interviews were analysed in rich detail. The major findings depict 251 themes from the qualitative data analysis categorised under 6 main categories. To validated and cross compare the themes, 9 collected interviews were audio listened to verify and validate the findings. In summary, based on stage 1 results, there is a gap in the development programmes provided by HR in HEIs, and MM requirements. Future study in Stage two (quantitative stage), will further explore MM development needs via pilot testing a survey questionnaire in the same post 1992 HEI before disseminating it externally to 141 UK HEIs providers (Gov. UK, 2017) for validation prior to proposing the final development model

Oncolog, Volume 37, Issue 03, July-September 1992

Retinoic acid/interferon combination shows promising response rates Cross-matching test helps find donors for patients in dire need of platelets Silicone gel-filled implants: Women should have the option to choosehttps://openworks.mdanderson.org/oncolog/1039/thumbnail.jp

Common GBA Variants in Parkinson\u27s Disease and Lewy Body Dementia Patients

Parkinson’s disease (PD) and Lewy Body Dementias (LBD) are two distinct synucleinopathies with a great amount of symptomatic and genetic overlap. This overlap can often lead to misdiagnosis. Misdiagnosis can result in improper therapy and therefore a poorer prognosis. LBD is a neuropath diagnosis with subcategories, but for the purpose of this project we discuss LBD as a whole. GBA is a gene common to both diseases with different effect sizes in each, although increasing severity of disease for both. Common is defined as a presence greater than 1% in healthy controls. GBA is found in 2-37% of Parkinson cases worldwide, with Ashkenazi Jews having the highest frequency of mutation. Our PD cohort is a clinical series, whereas our LBD cohort is a pathological series. A clinical LBD series can skew results as they are often misdiagnosed, so there is more certainty behind a pathological series. Here, we screened ~200 samples for E365K and T408M, two common GBA variants. We have reviewed the clinical implications of being a GBA carrier for both diseases and have identified differences. We have genotyped ~1200 LBD samples for these two common variants. Now that we know GBA plays a role in each disease, we can better understand the mechanism of pathogenesis and can identify potential therapy targets for GBA carriers. These therapeutic targets could be a gateway to cures and therapies for an otherwise incurable condition

Case study in six sigma methadology : manufacturing quality improvement and guidence for managers

This article discusses the successful implementation of Six Sigma methodology in a high precision and critical process in the manufacture of automotive products. The Six Sigma define–measure–analyse–improve–control approach resulted in a reduction of tolerance-related problems and improved the first pass yield from 85% to 99.4%. Data were collected on all possible causes and regression analysis, hypothesis testing, Taguchi methods, classification and regression tree, etc. were used to analyse the data and draw conclusions. Implementation of Six Sigma methodology had a significant financial impact on the profitability of the company. An approximate saving of US$70,000 per annum was reported, which is in addition to the customer-facing benefits of improved quality on returns and sales. The project also had the benefit of allowing the company to learn useful messages that will guide future Six Sigma activities

High birth weight as an important risk factor for infant leukemia

In this paper, we compared the birth weight distribution among 201 infant leukaemia (IL) cases with that of 440 noncancer controls enrolled in Brazil in 1999–2005. Compared with the general population and the stratum 2500–2999 g as reference, IL cases weighing 3000–3999 g presented an odds ratio (OR) of 1.68 (95% CI: 1.03–2.76), and those of 4000 g or more, an OR of 2.28 (95% CI: 1.08–4.75), Ptrend<0.01. Using hospital-based controls, the OR for 4000 g or more, compared to 2500–2999 g, was 1.30 (95% CI: 1.02–1.43) after adjusting for confounders (gender, income, maternal age, pesticide and hormonal exposure during pregnancy). The results suggest that high birth weight is associated with increased risk of IL

Starting a New Oral Oncology Agent in the Midst of the Pandemic

Abbey Kaler pictured. Breast Medical Oncology Kaler A, McClosky V, Raghavendra AS, Tripathy D. Oral Oncolytics: Using Remote Technology to Improve Access, Operational Efficiency, and Satisfaction. Clinical journal of oncology nursing. 2022;26(3):308-312. doi:10.1188/22.CJON.308-312https://openworks.mdanderson.org/aprn-week-22/1002/thumbnail.jp

The changing nature of risk and risk management: the challenge of borders, uncertainty and resilience

No abstract available