14 research outputs found
Systemic sclerosis, localized morphea, en coup de sabre and aortic regurgitation: A rare association
A 24-year-old male presented with Raynaud's phenomenon, digital
infarcts, salt and pepper pigmentation and characteristic facies. There
was gastrointestinal involvement clinically, endoscopically as well
radiologically. In view of these findings and the demonstration of
anti-nuclear antibodies with a homogeneous pattern of
immunofluorescence and ScL-70 antibodies, he was diagnosed as a case of
diffuse cutaneous systemic sclerosis. In addition, the patient had
plaques of localized morphea, en coup de sabre with facial hemiatrophy
on the left side, and mild aortic regurgitation (detected on
echocardiography). The occurrence of these rare associations of
localized plaques of morphea, en coup de sabre and aortic regurgitation
in a single case of systemic sclerosis is quite an exceptional and
interesting occurrence
Segmental anhidrosis with hyporeflexia associated with congenital spinal deformity: A Ross's syndrome variant or inverse Horner's syndrome?
A 39-year-old soldier presented with anhidrosis affecting both upper
extremities below the shoulders, the right side of the trunk below the
third rib in front and the third vertebra on the back, and the left
lower extremity below the inguinal ligament since 1992. Ten years later
in 2002, he was also found to have bilateral absence of Achilles reflex
and decreased right knee jerk. In addition, the patient was found to
have congenital spinal abnormalities in the form of block of vertebrae
C3-C4; decreased disc space C4-C5; and break in pars interarticularis
L5-S1 with decreased disc space. A total of seven cases of Ross
syndrome, Holmes-Adie syndrome (tonic pupil with lost tendon jerks)
with segmental anhidrosis, have been described in the literature. Our
case, however, did not have any pupillary abnormality. A case of
progressive isolated segmental anhidrosis has also been described. The
association of congenital spinal abnormality, which may be
pathognomonic in the causation of this progressive sudomotor
degeneration, is quite interesting in our case. The distribution of
anhidrosis on the right side is just below the level of sweating loss
sometimes described in lesions of superior sympathetic cervical
ganglion in Horner's syndrome
Ross syndrome with ANA positivity: A clue to possible autoimmune origin and treatment with intravenous immunoglobulin
A 28-year-old serving soldier presented with patchy areas of absence of sweating and blurring of vision. On examination he was found to have segmental anhidrosis, right sided tonic pupil and absent ankle jerks. Investigations revealed ANA positivity with no other abnormalities. He was treated with Intravenous immunoglobulin. This case of Ross syndrome is reported for its rarity as well as a clue to its probable autoimmune origin and treatment option with intravenous immunoglobulins