A study of the photocatalytic effects of aqueous suspensions of platinized semiconductor materials on the reaction rates of candidate redox reactions

The effectiveness of powdered semiconductor materials in photocatalyzing candidate redox reactions was investigated. The rate of the photocatalyzed oxidation of cyanide at platinized TiO2 was studied. The extent of the cyanide reaction was followed directly using an electroanalytical method (i.e. differential pulse polarography). Experiments were performed in natural or artificial light. A comparison was made of kinetic data obtained for photocatalysis at platinized powders with rate data for nonplatinized powders

Evaluation of non-intrusive flow measurement techniques for a re-entry flight experiment

This study evaluates various non-intrusive techniques for the measurement of the flow field on the windward side of the Space Shuttle orbiter or a similar reentry vehicle. Included are linear (Rayleigh, Raman, Mie, Laser Doppler Velocimetry, Resonant Doppler Velocimetry) and nonlinear (Coherent Anti-Stokes Raman, Laser-Induced Fluorescence) light scattering, electron-beam fluorescence, thermal emission, and mass spectroscopy. Flow-field properties were taken from a nonequilibrium flow model by Shinn, Moss, and Simmonds at the NASA Langley Research Center. Conclusions are, when possible, based on quantitative scaling of known laboratory results to the conditions projected. Detailed discussion with researchers in the field contributed further to these conclusions and provided valuable insights regarding the experimental feasibility of each of the techniques

Exploration of the Neuronal Subtype Specificity of an Ethanol Responsive Gene: Glycogen Synthase Kinase 3 Beta (Gsk3b)

Exploration of the Neuronal Subtype Specificity of an Ethanol Responsive Gene: Glycogen Synthase Kinase 3 Beta (Gsk3b) Dalton Huey, Depts. of Bioinformatics, Biology & Chemistry, A. van der Vaart, G. M. Harris, and M. F. Miles, with Dr. Sarah Golding, Dept. of Biology Previous work done in our laboratory revealed that Glycogen Synthase Kinase 3 Beta (Gsk3b) functions as a hub gene in a network of genes regulated by acute ethanol in the medial prefrontal cortex (mPFC) across a mouse genetic panel. Adult mice treated with acute ethanol showed increased phosphorylation of GSK3B on the Ser9 residue in prefrontal cortex. Subsequent viral-mediated overexpression of Gsk3bin mouse mPFC caused an increase in ethanol consumption and pharmacological inhibition of GSK3B decreased ethanol consumption. However, it is unknown what neuron subtypes are driving this change in behavior. Here, we provide evidence that deletion of Gsk3bin Camk2a+ glutamatergic neurons of the mPFC results in a decrease in ethanol consumption in both continuous and intermittent access drinking paradigms. Furthermore, we have recently designed and validated a plasmid for Cre-dependent overexpression of Gsk3b, along with a Cre-dependent reporter as a control. These plasmids are planned for use in conjunction with different Cre drivers for viral-mediated expression in any cell type. Dissection of the neural circuitry of this ethanol responsive pathway can lead to a better assessment of Gsk3bas a potential target for the treatment of alcohol use disorders. Work supported by grants R01A027581 and P50AA022537 to MFM.https://scholarscompass.vcu.edu/uresposters/1313/thumbnail.jp

Simultaneous optical and near-infrared linear spectropolarimetry of the earthshine

Aims: We aim to extend our current observational understanding of the integrated planet Earth spectropolarimetry from the optical to the near-infrared wavelengths. Major biomarkers like O$_{\rm 2}$ and water vapor are strong flux absorbents in the Earth atmosphere and some linear polarization of the reflected stellar light is expected to occur at these wavelengths. Methods: Simultaneous optical ($0.4-0.9$ $\mu$m) and near-infrared ($0.9-2.3$ $\mu$m) linear spectropolarimetric data of the earthshine were acquired by observing the nightside of the waxing Moon. The data have sufficient spectral resolution (2.51 nm in the optical, and 1.83 and 2.91 nm in the near-infrared) to resolve major molecular species present in the Earth atmosphere. Results: We find the highest values of linear polarization ($\ge 10\%$) at the bluest wavelengths, which agrees with the literature. Linear polarization intensity steadily decreases towards red wavelengths reaching a nearly flat value beyond $\sim$0.8 $\mu$m. In the near-infrared, we measured a polarization degree of $\sim4.5 \%$ for the continuum. We report the detection of molecular features due to O$_{2}$ at $0.760, 1.25 \mu$m and H$_{2}$O at 0.653$-$0.725 $\mu$m, 0.780$-$0.825 $\mu$m, 0.93 and 1.12 $\mu$m in the spectropolarimetric data; most of them show high linear polarimetry degrees above the continuum. In particular, the broad H$_{2}$O 1.12 $\mu$m band displays a polarimetric intensity as high as that of the blue optical. These features may become a powerful tool to characterize Earth-like planets in polarized light.Comment: 4 pages, 3 figures. Accepted for publication as Letter in Astronomy and Astrophysics on 23/01/201

Rotational modulation of the linear polarimetric variability of the cool dwarf TVLM 513−-46546

Aims: We aimed to monitor the optical linear polarimetric signal of the magnetized, rapidly rotating M8.5 dwarf TVLM 513$-$46546. Methods: $R$- and $I$-band linear polarimetry images were collected with the ALFOSC instrument of the 2.56-m Nordic Optical Telescope on two consecutive nights covering about 0.5 and 4 rotation cycles in the $R$ and $I$ filters, respectively. We also obtained simultaneous intensity curves by means of differential photometry. The typical precision of the data is $\pm$0.46\% ($R$), $\pm$0.35\% ($I$) in the linear polarization degree and $\pm$9 mmag ($R$), $\pm$1.6 mmag ($I$) in the differential intensity curves. Results: Strong and variable linear polarization is detected in the $R$ and $I$ filters, with values of maximum polarization ($p^{*}$ = 1.30$\pm$0.35 \%) similar for both bands. The intensity and the polarimetric curves present a sinusoid-like pattern with a periodicity of $\sim$1.98 h, which we ascribe to structures in TVLM 513$-$46's surface synchronized with rotation. We found that the peaks of the intensity and polarimetric curves occur with a phase difference of 0.18$\pm$0.01, and that the maximum of the linear polarization happens nearly half a period (0.59$\pm$0.03) after the radio pulse. We discussed different scenarios to account for the observed properties of the light curves.Comment: Accepted for publication in Astronomy and Astrophysic

Running Economy while Running in Extreme Cushioning and Normal Cushioning Running Shoes

The purpose of the study was to determine if running economy was influenced by wearing maximal cushioning shoes vs. control (neutral cushioning) shoes. (Please see Abstract in text

Non-intrusive flow measurements on a reentry vehicle

This study evaluates the utility of various non-intrusive techniques for the measurement of the flow field on the windward side of the Space Shuttle or a similar re-entry vehicle. Included are linear (Rayleigh, Raman, Mie, Laser Doppler Velocimetry, Resonant Doppler Velocimetry) and nonlinear (Coherent Anti-Stokes Raman, Laser Induced Fluorescence) light scattering, electron beam fluorescence, thermal emission and mass spectroscopy. Flow field properties are taken from a nonequilibrium flow model by Shinn, Moss and Simmonds at NASA Langley. Conclusions are, when possible, based on quantitative scaling of known laboratory results to the conditions projected. Detailed discussion with researchers in the field contributed further to these conclusions and provided valuable insights regarding the experimental feasibility of each of the techniques

Total syntheses of conformationally-locked difluorinated pentopyranose analogues and a pentopyranosyl phosphate mimetic

Trifluoroethanol has been elaborated, via a telescoped sequence involving a metalated difluoroenol, a difluoroallylic alcohol, [2,3]-Wittig rearrangement, and ultimately an RCM reaction and requiring minimal intermediate purification, to a number of cyclooctenone intermediates. Epoxidation of these intermediates followed by transannular ring opening or dihydroxylation, then transannular hemiacetalization delivers novel bicyclic analogues of pentopyranoses, which were elaborated (in one case) to an analogue of a glycosyl phosphate

Opinion diversity and the resilience of cooperation in dynamical networks

Across various scenarios, individuals cooperate with others to contribute towards a shared goal and ensure self-preservation. In game theory, the act of cooperation is considered as an individual producing some form of benefit to be utilised by others, under the expectation others will return the favour. In several scenarios, individuals make use of their own information to aid with their decision about who to connect and cooperate with. However, the choice of cooperation can be taken advantage of by opportunistic defectors, which can lead to significant disruption. This paper investigates how the diversity of opinion can contribute to the structure and mechanics of a dynamical network model and to the resilience of cooperation, by utilising a computational model where individuals make use of both public and private information to implement their decision. Our results show that increasing diversity leads to more stable, less connected and less prosperous networks coupled to more frequent, but shallower information cascades. Our work generally shows that the outcome of the conflict between cooperators and cheaters strongly depends on the interplay between population structure, individual decision making and individual opinions