On q-Deformed Supersymmetric Classical Mechanical Models

Based on the idea of quantum groups and paragrassmann variables, we presenta generalization of supersymmetric classical mechanics with a deformation parameter $q= \exp{\frac{2 \pi i}{k}}$ dealing with the $k =3$ case. The coordinates of the $q$-superspace are a commuting parameter $t$ and a paragrassmann variable $\theta$, where $$. The generator and covariant derivative are obtained, as well as the action for some possible superfields.Comment: No figures, 14 pages, Latex, revised versio

Simple implementation of complex functionals: scaled selfconsistency

We explore and compare three approximate schemes allowing simple implementation of complex density functionals by making use of selfconsistent implementation of simpler functionals: (i) post-LDA evaluation of complex functionals at the LDA densities (or those of other simple functionals); (ii) application of a global scaling factor to the potential of the simple functional; and (iii) application of a local scaling factor to that potential. Option (i) is a common choice in density-functional calculations. Option (ii) was recently proposed by Cafiero and Gonzalez. We here put their proposal on a more rigorous basis, by deriving it, and explaining why it works, directly from the theorems of density-functional theory. Option (iii) is proposed here for the first time. We provide detailed comparisons of the three approaches among each other and with fully selfconsistent implementations for Hartree, local-density, generalized-gradient, self-interaction corrected, and meta-generalized-gradient approximations, for atoms, ions, quantum wells and model Hamiltonians. Scaled approaches turn out to be, on average, better than post-approaches, and unlike these also provide corrections to eigenvalues and orbitals. Scaled selfconsistency thus opens the possibility of efficient and reliable implementation of density functionals of hitherto unprecedented complexity.Comment: 12 pages, 1 figur

J/psi couplings to charmed resonances and to pi

We present an evaluation of the strong couplings JD^(*)D^(*) and JD^(*)D^(*)pi by an effective field theory of quarks and mesons. These couplings are necessary to calculate pi+J/psi --> D^(*)+barD^(*) cross sections, an important background to the J/psi suppression signal in the quark-gluon plasma. We write down the general effective lagrangian and compute the relevant couplings in the soft pion limit and beyond.Comment: 11 pages, 4 figures, 2 reference added and minor comments, style changed to RevTe

Laccase activation in deep eutectic solvents

The research on alternative solvents and co-solvents is a relevant aspect when envisioning the improvement of biocatalytic reactions. Among these solvents and co-solvents, deep eutectic solvents (DES) may be considered as customizable new reaction media for biocatalysis. Accordingly, in this work, sixteen DES aqueous solutions, as well as of the individual DES components at the same conditions have been investigated in laccase-catalyzed reactions. Cholinium- and betaine-based DES formed with polyols at different molar ratio and concentrations were evaluated. The results reported show that in presence of most DES the laccase activity is preserved and, with a particular DES, enhanced up to 200%. Molecular docking studies demonstrated that while most DES components establish hydrogen-bonds with the enzyme amino acids, those that establish stronger interactions with the enzyme (expressed by absolute values of docking affinity energies) lead to an enhanced laccase activity. Finally, the laccase stability was evaluated in additional tests under extreme storage temperatures (60 ºC and -80 ºC). Although no significant protection to high temperatures was afforded by DES, an enhanced laccase activity when stored at low temperatures was found, at least up to 20 days. Combining experimental results and molecular docking this work shows that DES can be designed as co-solvents to improve biocatalytic reactions.This work was developed within the scope of the project CICECO-Aveiro Institute of Materials, FCT Ref. UID/CTM/50011/2019, financed by national funds through the FCT/MCTES and within the project POCI-01-0145-FEDER-031268 - funded by FEDER, through COMPETE2020 - Programa Operacional Competitividade e Internacionalização (POCI), and by national funds (OE), through FCT/MCTES. Mariah L. Toledo acknowledges University of São Paulo (Mobilidade internacional de duração 23especial). Ana P. M. Tavares acknowledges FCT for the Investigator Programme (IF/01634/2015). Matheus M. Pereira acknowledges the PhD grant (2740-13-3) and financial support from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Capes. João P. A. Silva acknowledges the support of FAPESP (Fundação de Amparo à Pesquisa do Estado de São Paulo-Process Number 2016/06683-0).publishe

Aqueous Biphasic Systems Comprising Natural Organic Acid-Derived Ionic Liquids

Despite the progress achieved by aqueous biphasic systems (ABSs) comprising ionic liquids (ILs) in extracting valuable proteins, the quest for bio‐based and protein‐friendly ILs continues. To address this need, this work uses natural organic acids as precursors in the synthesis of four ILs, namely tetrabutylammonium formate ([N4444][HCOO]), tetrabutylammonium acetate ([N4444][CH3COO]), tetrabutylphosphonium formate ([P4444][HCOO]), and tetrabutylphosphonium acetate ([P4444][CH3COO]). It is shown that ABSs can be prepared using all four organic acid‐derived ILs paired with the salts potassium phosphate dibasic (K2HPO4) and tripotassium citrate (C6H5K3O7). According to the ABSs phase diagrams, [P4444]‐based ILs outperform their ammonium congeners in their ability to undergo liquid–liquid demixing in the presence of salts due to their lower hydrogen‐bond acidity. However, deviations to the Hofmeister series were detected in the salts’ effect, which may be related to the high charge density of the studied IL anions. As a proof of concept for their extraction potential, these ABSs were evaluated in extracting human transferrin, allowing extraction efficiencies of 100% and recovery yields ranging between 86 and 100%. To further disclose the molecular‐level mechanisms behind the extraction of human transferrin, molecular docking studies were performed. Overall, the salting‐out exerted by the salt is the main mechanism responsible for the complete extraction of human transferrin toward the IL‐rich phase, whereas the recovery yield and protein‐friendly nature of these systems depend on specific “IL-transferrin” interactions.publishe

RANCANG BANGUN LEMARI PENGERING DAUN MARUNGGA (Moringa Oleifera)

Abstrak Pohon Marungga merupakan salah satu tumbuhan yang memiliki manfaat yang besar. Untuk daunnya sendiri dapat dijakdikan menjadi suplemen gizi dan juga sebagai bahan dasar kosmetik. Daun Marungga sendiri dapat dijadikan bubuk untuk selanjutnya diproses ke dalam berbagai kebutuhan. Sebelum dijadikan bubuk, sebelumnya daun tersebut harus dikeringkan. Pengeringan manual selama ini membutuhkan waktu yang panjang dan tidak higienis. Pada penelitian ini diperoleh hasil, proses pengeringan selama 19 jam diperolehhasil penurunan kelembaban tidak bisa dilakukan secara cepat. Hal ini disebabkan karena temperatur dalam ruangan tidak mampu memanaskan udara sekitar dengan cepat sehingga proses pengeringan cenderung lebih lambat. Dengan beban pengeringan 20 kg daun Marungga mentah, diperoleh sekitar 3 kg daun kering.Kata kunci: marungga; perpindahan panas; lemari Abstract Marungga tree is one of the plants that have great benefits. The leaves themselves can be transformed into nutritional supplements and also as a cosmetic base ingredient. Marungga leaves themselves can be used as a powder for further processing into various needs. Before being made into powder, the leaf must be dried beforehand. Manual drying so far requires a long time and is not hygienic. In this study the results were obtained, the drying process for19 hours obtained the result of humidity reduction could not be done quickly. This is because the temperature in the room is not able to heat the surrounding air quickly so the drying process tends to be slower. With a drying load of 20 kg of raw Marungga leaves, about 3 kg of dried leaves are obtained.Keywords: marungga; heat transfer; cabinet

Tailoring the partitioning of proteins using ionic liquids as adjuvants in polymer-polymer aqueous biphasic systems

Aqueous biphasic systems (ABS) are promising for proteins purification; however, when dealing with samples comprising several proteins, the selectivity towards a target protein is difficult to achieve. In this work, the addition of ionic liquids (ILs) as adjuvants (5 and 10 wt%) in ABS composed of polyethyleneglycol (PEG) and Dextran was investigated to tailor proteins’ partitioning between the coexisting phases. The liquid-liquid phase diagrams were determined at 298 K, followed by partition studies of three proteins (bovine serum albumin (BSA), immunoglobulin G (IgG), and cytochrome C (Cyt C)). Partition coefficients of IgG and BSA indicate the preference of both proteins to the dextran-rich phase, whereas Cyt C has no preferential partitioning between the phases. The addition of chloride-based ILs as adjuvants allows to increase or decrease the partition coefficients, thus tailoring the proteins partitioning between the phases. BSA partitioning essentially depends on the IL content in each phase, whereas Cyt C and IgG partitioning is ruled by the ILs chemical structure and established interactions. Molecular docking was carried out to address the ILs effect on the proteins partitioning, supporting experimental observations, while identifying the specific interactions occurring. The partition of each protein in polymer-salt ABS with ILs as adjuvants was determined, demonstrating the higher tailoring ability of polymer-polymer ABS when adding ILs. Finally, the partition of each protein in presence of the remaining ones was determined, as well as the selectivity of the studied systems to separate each pair of proteins, paving the way for their use in liquid-liquid chromatography.publishe

Synthesis and characterization of analogues of glycine-betaine ionic liquids and their use in the formation of aqueous biphasic systems

A series of novel analogues of glycine-betaine ionic liquids (AGB-ILs), viz. 1-(4-ethoxy-4-oxobutyl)-1-methylpyrrolidin-1-ium, N,N,N-tri(n-butyl)(4-ethoxy-4-oxobutyl)-1-phosphonium and N,N,N-trialkyl(4-ethoxy-4-oxobutyl)-1-aminium cations with ethyl, n-propyl and n-butyl alkyl chains, combined with the bromide anion, have been synthesized and characterized. Their synthesis and characterization by spectroscopic methods and elemental analysis is here reported. These ILs were further characterized in what concerns their thermal properties and ecotoxicity against Allvibrio fischeri, and compared with the commercial tetra(n-butyl)ammonium and tetra(n-butyl)phosphonium bromide. The novel AGB-ILs described in this work have low melting points, below 100 °C, display high degradation temperatures (180–310 °C), and low toxicity as shown by being harmless or practically harmless towards the marine bacteria Allvibrio fischeri. Finally, the ability of the synthesized AGB-ILs to form aqueous biphasic systems with potassium citrate/citric acid (at pH 7) was evaluated, and the respective ternary phase diagrams were determined. It is shown that the increase of the cation alkyl chain length facilitates the creation of ABS, and that phosphonium-based ILs present a slightly better separation performance in presence of aqueous solutions of the citrate-based salt.publishe

Understanding mobility in networks

Motivated by the growing number of mobile devices capable of connecting and exchanging messages, we propose a methodology aiming to model and analyze node mobility in networks. We note that many existing solutions in the literature rely on topological measurements calculated directly on the graph of node contacts, aiming to capture the notion of the node's importance in terms of connectivity and mobility patterns beneficial for prototyping, design, and deployment of mobile networks. However, each measure has its specificity and fails to generalize the node importance notions that ultimately change over time. Unlike previous approaches, our methodology is based on a node embedding method that models and unveils the nodes' importance in mobility and connectivity patterns while preserving their spatial and temporal characteristics. We focus on a case study based on a trace of group meetings. The results show that our methodology provides a rich representation for extracting different mobility and connectivity patterns, which can be helpful for various applications and services in mobile networks