18,734 research outputs found
Translational Invariance and the Anisotropy of the Cosmic Microwave Background
Primordial quantum fluctuations produced by inflation are conventionally
assumed to be statistically homogeneous, a consequence of translational
invariance. In this paper we quantify the potentially observable effects of a
small violation of translational invariance during inflation, as characterized
by the presence of a preferred point, line, or plane. We explore the imprint
such a violation would leave on the cosmic microwave background anisotropy, and
provide explicit formulas for the expected amplitudes of
the spherical-harmonic coefficients.Comment: Notation improve
Subclinical Photoreceptor Disruption in Response to Severe Head Trauma
Commotio retinae is a transient opacification of the retina due to outer retinal disruption occurring in a contrecoup fashion after blunt trauma.Histological studies in animals and humans after ocular blunt trauma have revealed that disruption occurs at the level of the photoreceptor outer segments and retinal pigment epithelium.Recent reports using optical coherence tomography (OCT) have shown detectable disruption at the level of the photoreceptor inner segment/outer segment junction and retinal pigment epithelium and that these changes may be reversible over time with restoration of normal outer retinal architecture.However, the resolution of existing OCT technology may not be sensitive enough to detect photoreceptor disruption. Adaptive optics (AO) imaging systems enable cellular-resolution imaging of the human retina, and there is a growing number of cases where deficits have been visible on AO images but not on OCT. Herein, we report a case of subclinical photoreceptor disruption after head trauma as seen by an AO scanning ophthalmoscope (AOSO) but not apparent clinically or on spectral-domain OCT (SD-OCT)
Evaluating Outer Segment Length as A Surrogate Measure of Peak Foveal Cone Density
Adaptive optics (AO) imaging tools enable direct visualization of the cone photoreceptor mosaic, which facilitates quantitative measurements such as cone density. However, in many individuals, low image quality or excessive eye movements precludes making such measures. As foveal cone specialization is associated with both increased density and outer segment (OS) elongation, we sought to examine whether OS length could be used as a surrogate measure of foveal cone density. The retinas of 43 subjects (23 normal and 20 albinism; aged 6–67 years) were examined. Peak foveal cone density was measured using confocal adaptive optics scanning light ophthalmoscopy (AOSLO), and OS length was measured using optical coherence tomography (OCT) and longitudinal reflectivity profile-based approach. Peak cone density ranged from 29,200 to 214,000 cones/mm2(111,700 ± 46,300 cones/mm2); OS length ranged from 26.3 to 54.5 μm (40.5 ± 7.7 μm). Density was significantly correlated with OS length in albinism (p \u3c 0.0001), but not normals (p = 0.99). A cubic model of density as a function of OS length was created based on histology and optimized to fit the albinism data. The model includes triangular cone packing, a cylindrical OS with a fixed volume of 136.6 μm3, and a ratio of OS to inner segment width that increased linearly with increasing OS length (R2 = 0.72). Normal subjects showed no apparent relationship between cone density and OS length. In the absence of adequate AOSLO imagery, OS length may be used to estimate cone density in patients with albinism. Whether this relationship exists in other patient populations with foveal hypoplasia (e.g., premature birth, aniridia, isolated foveal hypoplasia) remains to be seen
Abundance analysis, spectral variability, and search for the presence of a magnetic field in the typical PGa star HD19400
The aim of this study is to carry out an abundance determination, to search
for spectral variability and for the presence of a weak magnetic field in the
typical PGa star HD19400. High-resolution, high signal-to-noise HARPS
spectropolarimetric observations of HD19400 were obtained at three different
epochs in 2011 and 2013. For the first time, we present abundances of various
elements determined using an ATLAS12 model, including the abundances of a
number of elements not analysed by previous studies, such as Ne I, Ga II, and
Xe II. Several lines of As II are also present in the spectra of HD19400. To
study the variability, we compared the behaviour of the line profiles of
various elements. We report on the first detection of anomalous shapes of line
profiles belonging to Mn and Hg, and the variability of the line profiles
belonging to the elements Hg, P, Mn, Fe, and Ga. We suggest that the
variability of the line profiles of these elements is caused by their
non-uniform surface distribution, similar to the presence of chemical spots
detected in HgMn stars. The search for the presence of a magnetic field was
carried out using the moment technique and the SVD method. Our measurements of
the magnetic field with the moment technique using 22 Mn II lines indicate the
potential existence of a weak variable longitudinal magnetic field on the first
epoch. The SVD method applied to the Mn II lines indicates =-76+-25G on
the first epoch, and at the same epoch the SVD analysis of the observations
using the Fe II lines shows =-91+-35G. The calculated false alarm
probability values, 0.008 and 0.003, respectively, are above the value 10^{-3},
indicating no detection.Comment: 13+6 pages, 14 figures, 6+1 tables, including the online-only
material, accepted for publication in MNRA
Repeatability of \u3cem\u3eIn Vivo\u3c/em\u3e Parafoveal Cone Density and Spacing Measurements
Purpose. To assess the repeatability and measurement error associated with cone density and nearest neighbor distance (NND) estimates in images of the parafoveal cone mosaic obtained with an adaptive optics scanning light ophthalmoscope (AOSLO).Methods. Twenty-one participants with no known ocular pathology were recruited. Four retinal locations, approximately 0.65[degrees] eccentricity from the center of fixation, were imaged 10 times in randomized order with an AOSLO. Cone coordinates in each image were identified using an automated algorithm (with or without manual correction) from which cone density and NND were calculated. Owing to naturally occurring fixational instability, the 10 images recorded from a given location did not overlap entirely. We thus analyzed each image set both before and after alignment.Results. Automated estimates of cone density on the unaligned image sets showed a coefficient of repeatability of 11,769 cones/mm2 (17.1%). The primary reason for this variability appears to be fixational instability, as aligning the 10 images to include the exact same retinal area results in an improved repeatability of 4358 cones/mm2 (6.4%) using completely automated cone identification software. Repeatability improved further by manually identifying cones missed by the automated algorithm, with a coefficient of repeatability of 1967 cones/mm2 (2.7%). NND showed improved repeatability and was generally insensitive to the undersampling by the automated algorithm.Conclusions. As our data were collected in a young, healthy population, this likely represents a best-case estimate for corresponding measurements in patients with retinal disease. Similar studies need to be carried out on other imaging systems (including those using different imaging modalities, wavefront correction technology, and/or image analysis software), as repeatability would be expected to be highly sensitive to initial image quality and the performance of cone identification algorithms. Separate studies addressing intersession repeatability and interobserver reliability are also needed
Boundary fields and renormalization group flow in the two-matrix model
We analyze the Ising model on a random surface with a boundary magnetic field
using matrix model techniques. We are able to exactly calculate the disk
amplitude, boundary magnetization and bulk magnetization in the presence of a
boundary field. The results of these calculations can be interpreted in terms
of renormalization group flow induced by the boundary operator. In the
continuum limit this RG flow corresponds to the flow from non-conformal to
conformal boundary conditions which has recently been studied in flat space
theories.Comment: 31 pages, Late
Assessing the Spatial Relationship Between Fixation and Foveal Specializations
Increased cone photoreceptor density, an avascular zone (FAZ), and the displacement of inner retinal neurons to form a pit are distinct features of the human fovea. As the fovea provides the majority of our vision, appreciating how these anatomical specializations are related is important for understanding foveal development, normal visual function, and retinal disease. Here we evaluated the relationship between these specializations and their location relative to the preferred retinal locus of fixation (PRL). We measured foveal pit volume, FAZ area, peak cone density, and location of the PRL in 22 subjects with normal vision using optical coherence tomography and adaptive optics scanning light ophthalmoscopy. Foveal pit volume was positively correlated with FAZ area; however, peak cone density was not correlated with pit volume. In addition, there was no systematic offset of the location of any of these specializations relative to PRL, and there was no correlation between the magnitude of the offset from PRL and the corresponding foveal specialization measurements (pit volume, FAZ area, peak cone density). The standard deviation of our PRL measurements was consistent with previous measurements of fixational stability. These data provide insight into the sequence of events during foveal development and may have implications for visual function and retinal disease
Dark Energy and the mass of galaxy clusters
Up to now, Dark Energy evidences are based on the dynamics of the universe on
very large scales, above 1 Gpc. Assuming it continues to behave like a
cosmological constant on much smaller scales, I discuss its effects
on the motion of non-relativistic test-particles in a weak gravitational field
and I propose a way to detect evidences of at the scale of
about 1 Mpc: the main ingredient is the measurement of galaxy cluster masses.Comment: 5 pages, no figures, references adde
Cosmological model with non-minimally coupled fermionic field
A model for the Universe is proposed whose constituents are: (a) a dark
energy field modeled by a fermionic field non-minimally coupled with the
gravitational field, (b) a matter field which consists of pressureless baryonic
and dark matter fields and (c) a field which represents the radiation and the
neutrinos. The coupled system of Dirac's equations and Einstein field equations
is solved numerically by considering a spatially flat homogeneous and isotropic
Universe. It is shown that the proposed model can reproduce the expected
red-shift behaviors of the deceleration parameter, of the density parameters of
each constituent and of the luminosity distance. Furthermore, for small values
of the red-shift the constant which couples the fermionic and gravitational
fields has a remarkable influence on the density and deceleration parameters.Comment: Accepted for publication in Europhysics Letter
Yang-Mills Instantons with Lorentz Violation
An analysis is performed of instanton configurations in pure Euclidean
Yang-Mills theory containing small Lorentz-violating perturbations that
maintain gauge invariance. Conventional topological arguments are used to show
that the general classification of instanton solutions involving the
topological charge is the same as in the standard case. Explicit solutions are
constructed for general gauge invariant corrections to the action that are
quadratic in the curvature. The value of the action is found to be unperturbed
to lowest order in the Lorentz-violating parameters.Comment: 16 page
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