EFFECT OF RASA MEZHUGU ON FREUND'S ADJUVANT-INDUCED ARTHRITIS IN RATS

Objective: Rheumatoid arthritis is a long-lasting autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen the following rest. The goal of treatment is to reduce pain, decrease inflammation, and improve a person's overall functioning. In spite of tremendous development in the field of synthetic drugs during recent years, the side effects could not be avoided. Hence the current research focus is to develop less toxic drugs as early as feasible in the disease process.Methods: A 90 d old Wistar male rat was used for the research and was divided into four groups treated with Saline, Palm Jaggary, Rasa Mezhugu and Indomethacin.Results: Acute toxicity study, Sub Acute study, Anti-arthritic study and histological findings showed that the Rasa Mezhugu has an anti-arthritis effect.Conclusion: Further the histopathology slide photos of bone, cerebrum, cardiac muscle, kidney, liver, pancreas, ovaries, lungs, testes, stomach and spleen proved the safety of Rasa Mezhugu in rats

A REVIEW ON SIDDHA EXTERNAL THERAPY - NASIYAM (NASAL INSTILLATION)

Siddha system of medicine, one of the ancient, traditional Indian systems of medicine has unique diagnostic methods, therapeutics and treatment procedures. It has a vast range of external modalities of treatment for health management. This external management is classified into 32 types. They include minor surgical procedures and treatment procedures. These therapies are used both as mainstream and supportive therapies - both curative and prophylactic. Most of the therapies are aimed to maintain the equilibrium of the three humours (Vatham, Pitham, Kabam). Among them Nasiyam (Nasal instillation) is one of the external therapies which is a non-invasive procedure. Nasiyam is the process by which the drug is administered through nostrils. This is the treatment procedure to balance the Thirithodam in its normal level. This paper documents the efficacy of Nasiyam, methods of application, shelf life, effect of Nasiyam in treating various diseases, the list of single drug and compound drug formulations that can be used as Nasiyam, Indications and contraindications are discussed in detail. Nasiyam therapy is used to treat the diseases of vitiated Kabam such as migraine, sinusitis, bronchial asthma, nasal polyp etc

DETERMINATION OF DIAGNOSTIC SIGNIFICANCE OF WRIST CIRCUMETRIC SIGN IN SIDDHA SYSTEM OF MEDICINE

Aim: Determination of diagnostic significance of wrist circumetric sign in siddha system of medicine.Materials and methods: Patients are randomly selected between the age 13years to 70 years with selected diagnoses like Madhumegam, Athikuruthiazhutham (Hypertension), Thamaraganoi, Putrunoi, Kalanjagapadai (Psoriasis), Moolam, Powthiram (Perianal fistula), Vali azhal keel vayu, Pakkavatham, Karupaisathaikatti (Uterine fibroids).Results and observation: Most of the patients MKN values fell within the range of 9-9¾ fb. This range of 9-9¾ fb MKN, was observed in Athikuruthiazhutham, Putrunoi, Moolam, Powthiram, Thamaraganoi, Madhumegam, Pakkavatham, healthy volunteers. 8-8¾fb MKN range was observed in 41.5% of Kalanjagapadai and vali azhal keel vayu cases. 10 - 10¾fb was observed in 43.1 % of patients with Karuppaisathaikattigal (Uterine fibroids).Conclusion: Since all other diseases had non-specific Manikkadai nool range except the condition Karupaisathaikattigal (uterine fibroid), Manikkadai nool can be used to assess screening test in detecting the presence of uterine fibroids and cardiac diseases according to this study.