Monitoring of the microcapsule/liposome application on textile fabrics

In recent years, new technologies have led to the production of biofunctional textiles. These biofunctional textiles contain microscopic capsules of ingredients that break as the fabric rubs the skin, releasing the active agents. Absorption and desorption behaviour of active agents embedded into the different biofunctional textiles should be taken into account when determining the amount of active agents incorporated into these textiles and when following the delivery mechanism as the fabric comes in contact with the skin. In this work, an encapsulated active agent (a sun filter, ethyl hexyl methoxycinnamate [EHMC] into microcapsules or liposomes) was applied by foulard onto different fabrics. The amount of capsules and active agents embedded into the fibres were quantified by (1) weight difference between untreated and treated fabrics, (2) extraction with isopropanol in an ultrasound bath, or (3) extraction with isopropanol/water 50/50 in a soxhlet device. Sun filter detection of the extraction baths was followed by HPLC and by UV spectrophotometry. The results show that the real amount of the EHMC present in different textile substrates depends on the way that the active agent is trapped, the ionic character of the fibres and on the vehicles used.Peer Reviewe

Monitoring of the microcapsule/liposome application on textile fabrics

In recent years, new technologies have led to the production of biofunctional textiles. These biofunctional textiles contain microscopic capsules of ingredients that break as the fabric rubs the skin, releasing the active agents. Absorption and desorption behaviour of active agents embedded into the different biofunctional textiles should be taken into account when determining the amount of active agents incorporated into these textiles and when following the delivery mechanism as the fabric comes in contact with the skin. In this work, an encapsulated active agent (a sun filter, ethyl hexyl methoxycinnamate [EHMC] into microcapsules or liposomes) was applied by foulard onto different fabrics. The amount of capsules and active agents embedded into the fibres were quantified by (1) weight difference between untreated and treated fabrics, (2) extraction with isopropanol in an ultrasound bath, or (3) extraction with isopropanol/water 50/50 in a soxhlet device. Sun filter detection of the extraction baths was followed by HPLC and by UV spectrophotometry. The results show that the real amount of the EHMC present in different textile substrates depends on the way that the active agent is trapped, the ionic character of the fibres and on the vehicles used.Peer Reviewe

Modelling of natural gas releases from pressurised pipelines Phase 4 CFD modelling of realistic failure scenarios

Available from British Library Document Supply Centre-DSC:4274.8539(98/08) / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Textiles with gallic acid microspheres: in vitro release characteristics

The aim of this study was to demonstrate the skin penetration of an antioxidant, gallic acid (GA), encapsulated in poly-epsilon-caprolactone (PCL) microspheres and applied onto textile fabrics, by a specific in vitro percutaneous absorption methodology. Two techniques (particle size distribution and FTIR) were used to characterise the microspheres obtained. The amount of GA-loaded microspheres present in the biofunctional textiles was established before their use as a textile drug delivery system. More absorption and desorption of microspheres with GA for the polyamide fabric were found in comparison with cotton fabric. The percutaneous absorption results indicated that the skin penetration of GA released from PCL-microspheres that were applied directly to the skin was higher than when GA was embedded within biofunctional textiles, in conclusion, an interesting reservoir effect may be promoted when biofunctional textiles were used