186 research outputs found

    Do Managerial Economics Textbooks Cover Ethics and Corporate Social Responsibility?

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    The topic of ethics has increased in importance in the business school curriculum in recent years. Highly publicised ethical scandals at corporations such as Enron, Arthur Anderson, and Tyco International, along with public alarm in response to accounts of environmental degradation, child labour abuses, and financial inequities, have heightened awareness of ethics and corporate social responsibility (CSR) in all business contexts. Although many colleges and universities have stand-alone graduate and undergraduate level business ethics and CSR courses, business and economics faculty are increasingly encouraged to address topics of ethics and CSR in courses throughout the business curriculum. This review addresses whether current managerial economics textbooks include discussion of ethics and CSR.

    Examining the Interest of Business School Students and the Gender Gap in Careers of Data Science and Analytics

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    Professionals in the data science and analytics field are in high demand. Recently, business schools have introduced various academic programs to train students in those fields. However, what makes business school students interested in these career fields is not entirely known. Research questions such as who the major influencers are for business school students\u27 career choices or whether there are any differences between genders in terms of their awareness, readiness, and interest in data science and analytics careers remain to be answered. Therefore, this study examines the segmentation of business school students in how they prepare for careers, drivers of interest for careers in data science and analytics fields, differences between genders, and business school students\u27 major influencers. The results show that business school students can be divided into three different segments as Financial Return Seekers, Wholesome College Experience Seekers, and Role-Model Seekers. Using these segments colleges can better target students in raising their awareness, readiness, and interest for data science and analytics. Findings also show that both awareness and readiness positively affect a student\u27s interest in data science and analytics careers. There were also differences found between men and women, where women scored lower with awareness, interest, and readiness to pursue careers in data science and analytics. Lastly, the research provided that parents and faculty are the major influencers of business school students\u27 career decisions. Based on the results there are many opportunities for business school leadership and faculty to help students become more aware of the career path, with support around the identified segments, and efforts to increase participation of women with data science and analytics

    Modeling the Effects of Drug Binding on the Dynamic Instability of Microtubules

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    We propose a stochastic model that accounts for the growth, catastrophe and rescue processes of steady state microtubules assembled from MAP-free tubulin. Both experimentally and theoretically we study the perturbation of microtubule dynamic instability by S-methyl-D-DM1, a synthetic derivative of the microtubule-targeted agent maytansine and a potential anticancer agent. We find that to be an effective suppressor of microtubule dynamics a drug must primarily suppress the loss of GDP tubulin from the microtubule tip.Comment: 17 pages, 11 figures, to appear in Phys. Bio

    The benzophenanthridine alkaloid sanguinarine perturbs microtubule assembly dynamics through tubulin binding: a possible mechanism for its antiproliferative activity

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    Sanguinarine has been shown to inhibit proliferation of several types of human cancer cell including multidrug-resistant cells, whereas it has minimal cytotoxicity against normal cells such as neutrophils and keratinocytes. By analyzing the antiproliferative activity of sanguinarine in relation to its effects on mitosis and microtubule assembly, we found that it inhibits cancer cell proliferation by a novel mechanism. It inhibited HeLa cell proliferation with a half-maximal inhibitory concentration of 1.6±0.1μm. In its lower effective inhibitory concentration range, sanguinarine depolymerized microtubules of both interphase and mitotic cells and perturbed chromosome organization in mitotic HeLa cells. At concentrations of 2μm, it induced bundling of interphase microtubules and formation of granular tubulin aggregates. A brief exposure of HeLa cells to sanguinarine caused irreversible depolymerization of the microtubules, inhibited cell proliferation, and induced cell death. However, in contrast with several other microtubule-depolymerizing agents, sanguinarine did not arrest cell cycle progression at mitosis. In vitro, low concentrations of sanguinarine inhibited microtubule assembly. At higher concentrations (>40μm), it altered polymer morphology. Further, it induced aggregation of tubulin in the presence of microtubule-associated proteins. The binding of sanguinarine to tubulin induces conformational changes in tubulin. Together, the results suggest that sanguinarine inhibits cell proliferation at least in part by perturbing microtubule assembly dynamics

    Intramarital Status Differences Across Africa’s Educational Expansion

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154246/1/jomf12632_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154246/2/jomf12632.pd

    Sounds or Silence? Auditory Stimulus Effects on Fine Motor Skills

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    Unlike vision where we can select stimuli to either attend to or to avoid altogether, audition provides no such opportunity. Auditory stimuli, which permeate all aspects of life, can spur movement and set a pace for individuals performing tasks. If qualities of auditory stimulation were specifically controlled, task performance may be directly affected. The present study examined different controlled sound conditions during performance on a manual dexterity task (the game of Operation). It was found that, indeed, certain sound qualities do affect performance

    Peripherally inserted central catheter‐related deep vein thrombosis: contemporary patterns and predictors

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107486/1/jth12549.pd

    Peripherally inserted central catheter‐related deep vein thrombosis: contemporary patterns and predictors: reply

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/109637/1/jth12721.pd

    Human subjects requirements and economic education researchers

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    This paper presents the results of a web-based survey of economic educators who were asked about their knowledge and experience with human subjects research and the mandated federal protocols that govern such research at most American universities. The results indicate that while economic education researchers are experienced in conducting human subjects research and are aware of the federal regulations, they are not well informed about key details of the regulations. They are skeptical of the net benefits of the mandated protocols because of the perceived discouraging burdens of the paperwork that rarely result in significant modifications of their research projects. The authors conclude that recent calls for modifications to the federal regulations for classroom-based research projects may be justified given the opportunity costs of adhering to the regulations compared to the relatively low levels of perceived benefits

    Human subjects requirements and economic education researchers

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    This paper presents the results of a web-based survey of economic educators who were asked about their knowledge and experience with human subjects research and the mandated federal protocols that govern such research at most American universities. The results indicate that while economic education researchers are experienced in conducting human subjects research and are aware of the federal regulations, they are not well informed about key details of the regulations. They are skeptical of the net benefits of the mandated protocols because of the perceived discouraging burdens of the paperwork that rarely result in significant modifications of their research projects. The authors conclude that recent calls for modifications to the federal regulations for classroom-based research projects may be justified given the opportunity costs of adhering to the regulations compared to the relatively low levels of perceived benefits
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