2,603 research outputs found
Experimental Investigation of Air-Cooled Turbine Blades in Turbojet Engine. 7: Rotor-Blade Fabrication Procedures
An experimental investigation was conducted to determine the cooling effectiveness of a wide variety of air-cooled turbine-blade configurations. The blades, which were tested in the turbine of a - commercial turbojet engine that was modified for this investigation by replacing two of the original blades with air-cooled blades located diametrically opposite each other, are untwisted, have no aerodynamic taper, and have essentially the same external profile. The cooling-passage configuration is different for each blade, however. The fabrication procedures were varied and often unique. The blades were fabricated using methods most suitable for obtaining a small number of blades for use in the cooling investigations and therefore not all the fabrication procedures would be directly applicable to production processes, although some of the ideas and steps might be useful. Blade shells were obtained by both casting and forming. The cast shells were either welded to the blade base or cast integrally with the base. The formed shells were attached to the base by a brazing and two welding methods. Additional surface area was supplied in the coolant passages by the addition of fins or tubes that were S-brazed. to the shell. A number of blades with special leading- and trailing-edge designs that provided added cooling to these areas were fabricated. The cooling effectiveness and purposes of the various blade configurations are discussed briefly
Clinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderly
Age is one of the strongest predictors of cardiovascular disease (CVD) risk. Treatment with statins can significantly reduce CVD events and mortality in both primary and secondary prevention. Yet despite the high CVD risk among the elderly, there is underutilization of statins in this population (ie, the treatment-risk paradox). Few studies have investigated the use of statins in the elderly, particularly for primary prevention and, as a result, guidelines for treating the elderly are limited. This is likely due to: uncertainties of risk assessment in older individuals where the predictive value of individual risk factors is decreased; the need to balance the benefits of primary prevention with the risks of polypharmacy, health care costs, and adverse medication effects in a population with decreased life expectancy; the complexity of treating patients with many other comorbidities; and increasingly difficult social and economic concerns. As life expectancy increases and the total elderly population grows, these issues become increasingly important. JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) is the largest primary prevention statin trial to date and enrolled a substantial number of elderly adults. Among the 5695 JUPITER participants ≥70 years of age, the absolute CVD risk reduction associated with rosuvastatin was actually greater than for younger participants. The implications of this JUPITER subanalysis and the broader role of statins among older adults is the subject of this review
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NACA Research Memorandums
"An experimental investigation was conducted to determine the cooling effectiveness of a wide variety of air-cooled turbine-blade configurations. The blades, which were tested in the turbine of a - commercial turbojet engine that was modified for this investigation by replacing two of the original blades with air-cooled blades located diametrically opposite each other, are untwisted, have no aerodynamic taper, and have essentially the same external profile. The cooling-passage configuration is different for each blade, however" (p. 1)
The winds and currents mission concept
© The Author(s), 2019. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Rodriguez, E., Bourassa, M., Chelton, D., Farrar, J. T., Long, D., Perkovic-Martin, D., & Samelson, R. The winds and currents mission concept. Frontiers in Marine Science, 6, (2019): 438, doi:10.3389/fmars.2019.00438.The Winds and Currents Mission (WaCM) is a proposed approach to meet the need identified by the NRC Decadal Survey for the simultaneous measurements of ocean vector winds and currents. WaCM features a Ka-band pencil-beam Doppler scatterometer able to map ocean winds and currents globally. We review the principles behind the WaCM measurement and the requirements driving the mission. We then present an overview of the WaCM observatory and tie its capabilities to other OceanObs reviews and measurement approaches.ER was funded under NASA grant NNN13D462T. DC was funded under NASA grant NNX10AO98G. JF was funded under NASA grants NNX14AM71G and NNX16AH76G. DL was funded under NASA grant NNX14AM67G. DP-M was funded under NASA grant NNH13ZDA001N. RS was funded under NASA grant NNX14AM66G
Antibodies against Lysophosphatidic Acid Protect against Blast-Induced Ocular Injuries
Exposure to blast overpressure waves is implicated as the major cause of ocular injuries and resultant visual dysfunction in veterans involved in recent combat operations. No effective therapeutic strategies have been developed so far for blast-induced ocular dysfunction. Lysophosphatidic acid (LPA) is a bioactive phospholipid generated by activated platelets, astrocytes, choroidal plexus cells, and microglia and is reported to play major roles in stimulating inflammatory processes. The levels of LPA in the cerebrospinal fluid have been reported to increase acutely in patients with traumatic brain injury (TBI) as well as in a controlled cortical impact (CCI) TBI model in mice. In the present study, we have evaluated the efficacy of a single intravenous administration of a monoclonal LPA antibody (25 mg/kg) given at 1 h post-blast for protection against injuries to the retina and associated ocular dysfunctions. Our results show that a single 19 psi blast exposure significantly increased the levels of several species of LPA in blood plasma at 1 and 4 h post-blast. The anti-LPA antibody treatment significantly decreased glial cell activation and preserved neuronal cell morphology in the retina on day 8 after blast exposure. Optokinetic measurements indicated that anti-LPA antibody treatment significantly improved visual acuity in both eyes on days 2 and 6 post-blast exposure. Anti-LPA antibody treatment significantly increased rod photoreceptor and bipolar neuronal cell signaling in both eyes on day 7 post-blast exposure. These results suggest that blast exposure triggers release of LPAs, which play a major role promoting blast-induced ocular injuries, and that a single early administration of anti-LPA antibodies provides significant protection
Ursinus College Alumni Journal, July 1955
Commencement address 1955 • The college honors Dr. I. S. Leinbach • Ground broken for the new women\u27s dormitories • News from the registrar\u27s office • Armstrong preaches baccalaureate sermon • Summer program offered again at Ursinus • Meistersingers make spring tour • The magic hour May Day theme • New student union in Bomberger basement • Alpha Phi Omega campus project • Alumni celebrate graduation anniversary • Class of \u2755 elects permanent class officers • Keyser \u2710 and Krug \u2737 honored by educators • Alumni elect new officers for 1955-57 • York County alumni sponsor Noss film • J. A. Hunsicker \u2792 recipient of award • Regional alumni groups hold annual meetings • French Department faculty member active in research • Barbara Yerkes \u2749 teacher and friend of Bristol High students • Sports review • 1955 baseball season • 1955 tennis season • Varsity Club honors outstanding athletes • 1955 women\u27s sports • 1955 track season • Ursinus participates in Ford foundation program for teachers • Alumni participate in Red Lion jubilee • News about ourselves • Weddings • Birthshttps://digitalcommons.ursinus.edu/alumnijournal/1052/thumbnail.jp
Ursinus College Alumni Journal, November 1955
Program for new dormitories underway • Business, the alumnus, and the cost of higher education • Campbell Soup Company establishes fund • James Hirst named to honor society • 18th annual performance announced of the Messiah • Attendance increases in the Ursinus College Evening School • Some notes from the Dean\u27s office • Registrar\u27s report on fall enrollment • Ursinus forum 1955-1956 • Max C. Putney \u2718 author of The Man of Galilee • South Jersey alumni honor Dr. McClure • Binder named Dean at Thiel College • Berks County alumni hold clam bake • Dr. Sherman A. Eger \u2725 describes new operation for high blood pressure • James J. Herron \u2732 elected vice-president of Dun & Bradstreet, Inc. • Alumni eligible for Fulbright scholarships • Ursinus Women\u27s Club • Committee to review alumni constitution • A Fulbrighter in Japan • 1955 Loyalty Fund report • Sick transit - or - She perks no more • Curtain Club presents The Madwoman of Chaillot • Class of \u2756 elects permanent alumni officers • Mrs. Snyder new preceptress at Duryea Hall • G. E. reports on its corporate alumnus program • Regional alumni groups plan student trip • Warren K. Hess \u2731 addresses state school directors • 51\u27ers quartet meet after four years • History art collection • Sports review: Soccer report; Facts about the coaching staff; Alumni varsity basketball game • News about ourselves • Weddings • Births • Necrologyhttps://digitalcommons.ursinus.edu/alumnijournal/1054/thumbnail.jp
A serum calprotectin lateral flow test as an inflammatory and prognostic marker in acute lung infection: a prospective observational study
Ursinus College Alumni Journal, March 1956
President\u27s page • Sigma Rho scholarship fund grows • Three Ursinus alumni honored at Founders\u27 Day ceremony • 191,400 to Ursinus College • Enrollment increases in Evening School • Notes from the Dean\u27s office • Ursinus presentation of Messiah recorded • From the Office of Admissions • Faculty corner • Philadelphia alumni to meet at Casa Conti • Plan now to return Alumni Day, June 2 • Spring banquet planned by Lehigh Valley • May 2nd, date for New York alumni • South Jersey alumni plan dinner-dance • Woman\u27s Club plans spring activities • Booster committee holds banquet for athletes • Ditter, Warden, Tredinnick, Assistant District Attorneys • Alumni invited to Varsity Club dinner • Dr. Gilbert Bayne \u2743 speaks to science societies • Isaac Norris of Norristown, PA • Alumni elections • Schoolmen\u27s Week teachers luncheon • Washington area alumni reorganize • Report of the loyalty fund campaign • Sports review: Football season 1955; Dave Burger named to All-American soccer team; Soccer season 1955; Wrestling; 1955 alumnae hockey; Heller and Dawkins excel in women\u27s hockey • News about ourselves • Births • Weddings • Necrologyhttps://digitalcommons.ursinus.edu/alumnijournal/1055/thumbnail.jp
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