5 research outputs found

    The mutually reinforcing relation between international migration of highly educated labour force and economic crisis: the case of Greece

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    Although several studies aim at analysing the causes and impacts of the current economic crisis, especially involving the case of Greece, the role that highly educated population holds has not received wider attention. Based on an examination of both secondary data on the Greek economy/labour market and primary data collected by a survey that included 1821 graduates, this paper shows that underutilization of highly educated population harmed the competitiveness of the Greek economy, a factor which has significantly contributed to the creation of the current debt crisis and fostered the migration of graduates

    Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium.

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    Left-right asymmetry is an important organizing feature of the healthy brain that may be altered in schizophrenia, but most studies have used relatively small samples and heterogeneous approaches, resulting in equivocal findings. We carried out the largest case-control study of structural brain asymmetries in schizophrenia, with MRI data from 5,080 affected individuals and 6,015 controls across 46 datasets, using a single image analysis protocol. Asymmetry indexes were calculated for global and regional cortical thickness, surface area, and subcortical volume measures. Differences of asymmetry were calculated between affected individuals and controls per dataset, and effect sizes were meta-analyzed across datasets. Small average case-control differences were observed for thickness asymmetries of the rostral anterior cingulate and the middle temporal gyrus, both driven by thinner left-hemispheric cortices in schizophrenia. Analyses of these asymmetries with respect to the use of antipsychotic medication and other clinical variables did not show any significant associations. Assessment of age- and sex-specific effects revealed a stronger average leftward asymmetry of pallidum volume between older cases and controls. Case-control differences in a multivariate context were assessed in a subset of the data (N = 2,029), which revealed that 7% of the variance across all structural asymmetries was explained by case-control status. Subtle case-control differences of brain macrostructural asymmetry may reflect differences at the molecular, cytoarchitectonic, or circuit levels that have functional relevance for the disorder. Reduced left middle temporal cortical thickness is consistent with altered left-hemisphere language network organization in schizophrenia

    Dopamine Systems in the Forebrain

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