Quantum computing with nearest neighbor interactions and error rates over 1%

Large-scale quantum computation will only be achieved if experimentally implementable quantum error correction procedures are devised that can tolerate experimentally achievable error rates. We describe a quantum error correction procedure that requires only a 2-D square lattice of qubits that can interact with their nearest neighbors, yet can tolerate quantum gate error rates over 1%. The precise maximum tolerable error rate depends on the error model, and we calculate values in the range 1.1--1.4% for various physically reasonable models. Even the lowest value represents the highest threshold error rate calculated to date in a geometrically constrained setting, and a 50% improvement over the previous record.Comment: 4 pages, 8 figure

Bird Monitoring at Homestead National Monument of America, Nebraska, Status Report 2009–2017

Executive Summary In 2009, the Heartland Inventory Monitoring Network initiated breeding bird surveys on Homestead National Monument of America, Nebraska, to address two objectives: (1) to monitor changes in bird community composition and abundance, and (2) to improve our understanding of relationships between breeding birds and habitat, and the effects of management actions on those relationships. This report evaluates trends in the park’s breeding bird populations in the context of trends observed within the North American Bird Conservation Initiative’s (NABCI) Central Mixed Grass Prairie Bird Conservation Region, the region in which the park is located. By doing so, we can assess the influence of park habitat management on bird populations with an understanding of regional population trends that are outside the influence of natural resource management activities at the Homestead national Monument of America. Eighty-six species of birds were recorded during May and June site visits in the nine years since initiating monitoring. Seventy-four of the species are considered breeding species because they are permanent or summer residents. Two of the breeding species recorded on Homestead National Monument of America are species of concern for the Central Mixed Grass Prairie Bird Conservation Region. Thirteen species were observed during the survey period in sufficient numbers to calculate annual abundances and trends with some degree of confidence. The American Goldfinch (Spinus tristis), Dickcissel (Spiza americana), House Wren (Troglodytes aedon), and Red-winged Blackbird (Agelaius phoeniceus) were the most abundant and widespread species on Homestead National Monument of America. Comparing population trends of the thirteen most recorded species on the park with regional trends for the Central Mixed Grass Prairie Bird Conservation Region were inconclusive, but suggest that trends in populations on the park were similar to trends in populations found region-wide for most species present. However, some differences in population trends were observed between the park and the region. This report provides current regional and local trends for breeding birds for future comparisons with bird data collected as part of the long-term monitoring efforts at Homestead National Monument of America. This information will help park staff plan management objectives, and assess the effectiveness of management alternatives. These monitoring data also provide park staff with additional information for interpreting natural resources

The Chemical Compositions of the Type II Cepheids -- The BL Her and W Vir Variables

Abundance analyses from high-resolution optical spectra are presented for 19 Type II Cepheids in the Galactic field. The sample includes both short-period (BL Her) and long-period (W Vir) stars. This is the first extensive abundance analysis of these variables. The C, N, and O abundances with similar spreads for the BL Her and W Vir show evidence for an atmosphere contaminated with $3\alpha$-process and CN-cycling products. A notable anomaly of the BL Her stars is an overabundance of Na by a factor of about five relative to their presumed initial abundances. This overabundance is not seen in the W Vir stars. The abundance anomalies running from mild to extreme in W Vir stars but not seen in the BL Her stars are attributed to dust-gas separation that provides an atmosphere deficient in elements of high condensation temperature, notably Al, Ca, Sc, Ti, and $s$-process elements. Such anomalies have previously been seen among RV Tau stars which represent a long-period extension of the variability enjoyed by the Type II Cepheids. Comments are offered on how the contrasting abundance anomalies of BL Her and W Vir stars may be explained in terms of the stars' evolution from the blue horizontal branch.Comment: 41 pages including 11 figures and 4 tables; Accepted for publication in Ap

Replication fork regression in vitro by the Werner syndrome protein (WRN): Holliday junction formation, the effect of leading arm structure and a potential role for WRN exonuclease activity

The premature aging and cancer-prone disease Werner syndrome stems from loss of WRN protein function. WRN deficiency causes replication abnormalities, sensitivity to certain genotoxic agents, genomic instability and early replicative senescence in primary fibroblasts. As a RecQ helicase family member, WRN is a DNA-dependent ATPase and unwinding enzyme, but also possesses strand annealing and exonuclease activities. RecQ helicases are postulated to participate in pathways responding to replication blockage, pathways possibly initiated by fork regression. In this study, a series of model replication fork substrates were used to examine the fork regression capability of WRN. Our results demonstrate that WRN catalyzes fork regression and Holliday junction formation. This process is an ATP-dependent reaction that is particularly efficient on forks containing single-stranded gaps of at least 11–13 nt on the leading arm at the fork junction. Importantly, WRN exonuclease activity, by digesting the leading daughter strand, enhances regression of forks with smaller gaps on the leading arm, thus creating an optimal structure for regression. Our results suggest that the multiple activities of WRN cooperate to promote replication fork regression. These findings, along with the established cellular consequences of WRN deficiency, strongly support a role for WRN in regression of blocked replication forks