Short Distance Expansion from the Dual Representation of Infinite Dimensional Lie Algebras

We compute the short distance expansion of fields or operators that live in the coadjoint representation of an infinite dimensional Lie algebra by using only properties of the adjoint representation and its dual. We explicitly compute the short distance expansion for the duals of the Virasoro algebra, affine Lie Algebras and the geometrically realized N-extended supersymmetric GR Virasoro algebra.Comment: 19 pages, LaTeX twice, no figure, replacement has corrected Lie algebr

Mitoxantrone is superior to doxorubicin in a multiagent weekly regimen for patients older than 60 with high-grade lymphoma: results of a BNLI randomized trial of PAdriaCEBO versus PMitCEBO

A prospective, multicenter, randomized trial was undertaken to compare the efficacy and toxicity of adriamycin with mitoxantrone within a 6-drug combination chemotherapy regimen for elderly patients (older than 60 years) with high-grade non-Hodgkin lymphoma (HGL) given for a minimum of 8 weeks. A total of 516 previously untreated patients aged older than 60 years were randomized to receive 1 of 2 anthracycline-containing regimens: adriamycin, 35 mg/m2 intravenously (IV) on day 1 (n = 259), or mitoxantrone, 7 mg/m2 IV on day 1 (n = 257); with prednisolone, 50 mg orally on days 1 to 14; cyclophosphamide, 300 mg/m2 IV on day 1; etoposide, 150 mg/m2 IV on day 1; vincristine, 1.4 mg/m2 IV on day 8; and bleomycin, 10 mg/m2 IV on day 8. Each 2-week cycle was administered for a minimum of 8 weeks in the absence of progression. Forty-three patients were ineligible for analysis. The overall and complete remission rates were 78% and 60% for patients receiving PMitCEBO and 69% and 52% for patients receiving PAdriaCEBO (P = .05, P = .12, respectively). Overall survival was significantly better with PMitCEBO than PAdriaCEBO (P = .0067). However, relapse-free survival was not significantly different (P = .16). At 4 years, 28% of PAdriaCEBO patients and 50% of PMitCEBO patients were alive (P = .0001). Ann Arbor stage III/IV, World Health Organization performance status 2-4, and elevated lactate dehydrogenase negatively influenced overall survival from diagnosis. In conclusion, the PMitCEBO 8-week combination chemotherapy regimen offers high response rates, durable remissions, and acceptable toxicity in elderly patients with HGL

Supergravity loop contributions to brane world supersymmetry breaking

We compute the supergravity loop contributions to the visible sector scalar masses in the simplest 5D `brane-world' model. Supersymmetry is assumed to be broken away from the visible brane and the contributions are UV finite due to 5D locality. We perform the calculation with N = 1 supergraphs, using a formulation of 5D supergravity in terms of N = 1 superfields. We compute contributions to the 4D effective action that determine the visible scalar masses, and we find that the mass-squared terms are negative.Comment: 12 pages, LaTeX 2

Supersymmetry Breaking in Warped Geometry

We examine the soft supersymmetry breaking parameters in supersymmetric theories on a slice of AdS_5 which generate the hierarchical Yukawa couplings by dynamically localizing the bulk matter fields in extra dimension. Such models can be regarded as the AdS dual of the recently studied 4-dimensional models which contain a supersymmetric CFT to generate the hierarchical Yukawa couplings. In such models, if supersymmetry breaking is mediated by the bulk radion superfield and/or some brane chiral superfields, potentially dangerous flavor-violating soft parameters can be naturally suppressed, thereby avoiding the SUSY flavor problem. We present some models of radion-dominated supersymmetry breaking which yield a highly predictive form of soft parameters in this framework.Comment: 17 pages, no figures, uses JHEP clas

An action for F-theory: SL(2)R+ exceptional field theory

DSB is supported by the STFC grant ST/L000415/1 'String Theory, Gauge Theory and Duality'. CB is supported in part by the Belgian Federal Science Policy Office through the Interuniversity Attraction Pole P7/37 'Fundamental Interactions', and in part by the 'FWO-Vlaanderen' through the project G.0207.14N and by the Vrije Universiteit Brussel through the Strategic Research Program 'High-Energy Physics'. EM is supported by the ERC Advanced Grant "Strings and Gravity' (Grant No. 32004). FJR is supported by an STFC studentship