22 research outputs found
Additional file 1: of Characteristics of an optimized patient information material for elderly patients with obstructive pulmonary diseases based on patients’ and experts’ assessment
Annex 1. Questions to patients and HCPs in our research. (DOCX 12 kb
Clinical data and circulating hyaluronan levels of the four study groups.
<p>ANP – asthmatic non-pregnant; AP – asthmatic pregnant; FEV<sub>1</sub>– forced expiratory volume in 1 second; PEF – peak expiratory flow rate; R<sub>aw</sub> – airway resistance; ACT – Asthma Control Test; ICS – inhaled corticosteroids; NA-not applicable. All p values>0.05 except for age where p = 0.0005.</p
Cut-off values of the inflammatory markers.
<p>Table shows the cut-off values of the inflammatory markers to discriminate between patients with PEF above and below 80% and ACT total score above and below 20, respectively in the asthmatic non-pregnant (ANP) and asthmatic pregnant (AP) groups.</p><p>PEF – peak expiratory flow rate; CRP – C-reactive protein; suPAR – soluble urokinase plasminogen activator receptor; IL-6 – interleukin 6; ACT – asthma control test; * p < 0.05.</p
Negative correlation between HA levels and ACT total scores in the asthmatic non-pregnant group.
<p>HA – hyaluronic acid; ACT – Asthma Control Test; p = 0.01; r = −0.437.</p
Correlation between HA levels and airway resistance in the asthmatic non-pregnant group.
<p>HA – hyaluronic acid; Raw – Airway Resistance; p = 0.004; r = 0.467.</p
Circulating CRP (A), suPAR (B) and IL-6 (C) levels measured in healthy non-pregnant and pregnant, and asthmatic non-pregnant and pregnant subjects.
<p>HNP – healthy non-pregnant; HP – healthy pregnant; ANP – asthmatic non-pregnant; AP – asthmatic pregnant; CRP – C-reactive protein; suPAR – soluble urokinase plasminogen activator receptor; IL-6 – interleukin 6; <sup>a</sup>p<0.05 vs. HNP, <sup>b</sup>p<0.05 vs. HP and <sup>c</sup>p<0.05 vs. ANP.</p
ROC analysis of HA values in asthmatic non-pregnant patients with controlled and uncontrolled disease according to ACT total score.
<p>HA – hyaluronic acid; ACT – asthma control test.</p
ROC analyses of suPAR values in asthmatic non-pregnant patients (A, B) and asthmatic pregnant patients (C, D) with good and impaired asthma control.
<p>ANP – asthmatic non-pregnant, AP – asthmatic pregnant; PEF – peak expiratory flow rate, ACT – Asthma Control Test total score.</p
Positive correlation of airway resistance (R<sub>aw</sub>) to circulating suPAR (A) and to circulating IL-6 (B) levels in asthmatic non-pregnant patients.
<p>suPAR – soluble urokinase plasminogen activator receptor; IL-6 – interleukin 6.</p
Circulating HA levels measured in asthmatic pregnant and non-pregnant women*.
<p>HA – hyaluronic acid; ANP – asthmatic non-pregnant; AP – asthmatic pregnant; p = 0.006; *data not adjusted for age.</p