3 research outputs found
Additional file 2 of Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis
Additional file 2. The predicted E3 ubiquitin ligases of RDX. (a) UbiBrowser was used to predict the E3 ubiquitin ligases of the RDX. (b) RT-PCR was performed to verify the knockdown efficiency of the main E3 ubiquitin ligases in GC cells
Additional file 1 of Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis
Additional file 1. ICAM2 plays tumourāsuppressive roles in GC cell. (a) The efficiency ICAM2 overexpression or knockdown were confirmed by RT-PCR. (b) Flow cytometry analysis of the effect of ICAM2 overexpression or knockdown on the cell cycle progression of GC cells. (c) Flow cytometry results showing the effect of ICAM2 overexpression or knockdown on the apoptosis of GC cells. (d) Representative image of the wound healing assays
Additional file 3 of Intercellular adhesion molecule 2 as a novel prospective tumor suppressor induced by ERG promotes ubiquitination-mediated radixin degradation to inhibit gastric cancer tumorigenicity and metastasis
Additional file 3. Restoration of RDX reverses the antitumor effect of ICAM2 overexpression in GC. (a) The efficiency of RDX overexpression was confirmed by RT-PCR. (b) Representative image of the wound healing assays. (c) The apoptosis of ICAM2-overexpressing cells treated with RDX was confirmed by flow cytometry. (d) Transfection efficiency after overexpression of RDX in GC cells was determined by western blot