Additional file 1: of Selection bias in clinical stroke trials depending on ability to consent

Full dataset supporting the manuscript. (CSV 60 kb

Demographic and clinical characteristics of the patient sample.

<p><i>Note.</i> Groups: SA =  subacute, CH =  chronic, CG =  control group. Pt =  patient; M/F =  male/female. NIHSS: National Institutes of Health Stroke Scale. Stroke etiology: i =  ischemic, h =  hemorrhagic stroke. V&TDS: visual and tactile double stimulation. CAV screen: CAV visual field screening. CAV-ET: CAV extinction test. NET Score: for subtests 1 to 8 and for the whole test battery. Mean (M) and standard deviation (SD) given for patients and healthy controls.</p

Schematical drawing of the CM.

<p>Schematical drawing of the CM.</p

Lesion patterns of individual patients.

<p>Patient numbers correspond to patient IDs in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0082892#pone-0082892-t001" target="_blank">Table 1</a> (patients #2-10). No MRI was available for patient #1. Right side of the brain corresponds to right hemisphere.</p

Results in visuo-constructive tests separated for patients and controls, left and right visual field.

<p>Dice Task (a) and Puzzle Test (b) are CM subtests, Copy Task (c) and Clock Drawing Test (d) are NET subtests. Diagrams show means and standard errors, L: left, R: right. Maximum achievable score per side: Puzzle: 10, Copy Task: 7, Clock Drawing Test: 2.</p

Layout of Dice Task (a) and Puzzle Test (b).

<p>In the Dice Task, patients were asked to use all dots and create a dice pattern. In the Puzzle Test, patients were required to select the correct pieces (from the left and right screen) to create the puzzle in the middle screen.</p

Star Cancellation Test: Percentage of detected stars, split into test-system, experimental group and visual field.

<p>The figure shows means and standard errors. Best possible performance (100%) in NET was 27 stars, in CM 20 stars per side. CM: Circle-Monitor, NET: Neglect-Test.</p

Variables included in the discriminant analysis.

<p><i>Note.</i> CM: Circle Monitor. NET: Neglect Test. Explained variance: explained variance by the given predictors. Stars (*) indicate significant predictors in the discriminant analyses.</p

Rating of the CM assessment: Number of affirming responses.

<p>Rating of the CM assessment: Number of affirming responses.</p

Results of the standard neuropsychological tests.

<p><i>Note.</i> V&TDS: visual and tactile double stimulation. CAV screen: CAV visual field screening. CAV-ET: CAV extinction test. NET Score: for subtests 1 to 8 and for the whole test battery. N: Number of patients/controls. M: Mean, SD: Standard deviation. Df: Degrees of freedom. Stars (*) indicate significant group differences.</p