1,782 research outputs found

    State Complexity of Regular Tree Languages for Tree Matching

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    We study the state complexity of regular tree languages for tree matching problem. Given a tree t and a set of pattern trees L, we can decide whether or not there exists a subtree occurrence of trees in L from the tree t by considering the new language L′ which accepts all trees containing trees in L as subtrees. We consider the case when we are given a set of pattern trees as a regular tree language and investigate the state complexity. Based on the sequential and parallel tree concatenation, we define three types of tree languages for deciding the existence of different types of subtree occurrences. We also study the deterministic top-down state complexity of path-closed languages for the same problem.</jats:p

    Third-order exceptional point in an ion-cavity system

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    We investigate a scheme for observing the third-order exceptional point (EP3) in an ion-cavity setting. In the lambda-type level configuration, the ion is driven by a pump field, and the resonator is probed with another weak laser field. We exploit the highly asymmetric branching ratio of an ion's excited state to satisfy the weak-excitation limit, which allows us to construct the non-Hermitian Hamiltonian (HnH)(H_{\textrm{nH}}). Via fitting the cavity-transmission spectrum, the eigenvalues of HnHH_{\textrm{nH}} are obtained. The EP3 appears at a point where the Rabi frequency of the pump laser and the atom-cavity coupling constant balance the loss rates of the system. Feasible experimental parameters are provided.Comment: 9 pages, 6 figure

    Diagnostic Performance of Core Needle Biopsy and Fine Needle Aspiration Separately or Together in the Diagnosis of Intrathoracic Lesions Under C-arm Guidance

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    Purpose: To evaluate and compare the diagnostic accuracy of fine needle aspiration (FNA) and core needle biopsy (CNB) of intrathoracic lesions using the same coaxial guide-needle under a C-arm Cone-Beam computed tomography system. Materials and Methods: Two hundred and eighty-eight patients (181 male, 107 female; 65.8 ± 13.3 years) with 293 lesions underwent 300 procedures, in which both FNA and CNB were performed. After inserting the coaxial guide-needle into the target lesion, we performed 18-gauge CNB, followed by 20-gauge FNA through the same coaxial guide-needle. The comparison of the procedures in which both showed adequate sample was performed with McNemar’s test (n = 229). Results: Of 300 procedures, 293 were technically successful. Adequate samples were obtained in 248/300 FNA and 288/300 CNB cases. The sensitivity and specificity for diagnosis of malignancy were respectively 84.7% (133/157), 100% (72/72) for FNA, when atypical cells included benign entity; 97.5% (153/157), 100% (72/72) for FNA, when atypical cells included malignancy; 97.6% (162/166), 100% (102/102) for CNB; and 100% (166/166), 100% (102/102) for combined FNA and CNB. Diagnosis of malignancy was significantly higher for CNB than for FNA ('p' < 0.001); however, it was not significantly higher when atypical cells included malignancy for FNA. Pneumothorax occurred in 50 (16.7%) and hemoptysis in 18 (6.0%) procedures. Conclusions: Combined use of CNB and FNA using the same coaxial guide-needle showed better diagnostic performance than using one alone. When comparing CNB and FNA, CNB showed significantly better performance, when atypical cells included a benign entity in FNA

    Evaluation of an immunochromatographic assay for the detection of anti-hepatitis A virus IgM

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    <p>Abstract</p> <p>Background</p> <p>Hepatitis A virus (HAV) is a causative agent of acute hepatitis, which is transmitted by person-to-person contact and via the faecal-oral route. Acute HAV infection is usually confirmed by anti-HAV IgM detection. In order to detect anti-HAV IgM in the serum of patients infected with HAV, we developed a rapid assay based on immunochromatography (ICA) and evaluated the sensitivity of this assay by comparing it with a commercial microparticle enzyme immunoassay (MEIA) that is widely used for serological diagnosis.</p> <p>Results</p> <p>The newly developed ICA showed 100% sensitivity and specificity when used to test 150 anti-HAV IgM-positive sera collected from infected patients and 75 negative sera from healthy subjects. Also, the sensitivity of ICA is about 10 times higher than MEIA used in this study by determining end point to detect independent on infected genotype of HAV. In addition, the ICA was able to detect 1 positive sample from among 50 sera from acute hepatitis patients that had tested negative for anti-HAV IgM using the MEIA.</p> <p>Conclusion</p> <p>Conclusively, ICA for the detection of anti-HAV IgM will be very effective for rapid assay to apply clinical diagnosis and epidemiological investigation on epidemics due to the simplicity, rapidity and specificity.</p
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