In situ conjugation of dithiophenol maleimide polymers and oxytocin for stable and reversible polymer–peptide conjugates

The in situ one-pot synthesis of peptide–polymer bioconjugates is reported. Conjugation occurs efficiently without the need for purification of dithiophenol maleimide functionalized polymer as a disulfide bridging agent for the therapeutic oxytocin. Conjugation of polymers was demonstrated to be reversible and to significantly improve the solution stability of oxytocin

PEG−peptide conjugates

The remarkable diversity of the self-assembly behavior of PEG−peptides is reviewed, including self-assemblies formed by PEG−peptides with β-sheet and α-helical (coiled-coil) peptide sequences. The modes of self-assembly in solution and in the solid state are discussed. Additionally, applications in bionanotechnology and synthetic materials science are summarized

Designing and modeling doubly porous polymeric materials

International audienc

Conception de matériaux polymères fonctionnalisés à double porosité

National audienc

Conception de matériaux polymères fonctionnalisés à double porosité

International audienc

Versatile functionalization platform of biporous poly(2-hydroxyethylmethacrylate)-based materials: Application in heterogeneous supportedcatalysis

International audienc