Synthesis of nem paramagnetic retinal analogues

New paramagnetic retinal analogues have been synthesized by Horner-Wadsworth-Emmons and Wittig reactions. In these new analogues the pyrroline nitroxide moiety is situated in the place of Beta-ionone ring or at the end of the polyene chain

Synthesis of Azoles Condensed with, or Linked to, Nitroxides

Nitroxides connected to indoles, tetrazoles, or 1,3,4-oxadiazoles were synthesized by conventional and microwave-assisted cyclization reactions. New approaches to pyrrole-, pyrazole-, and triazoleannulated nitroxides are described. We showed that Diels–Alder reactions of the N-tert-butoxycarbonyl derivative of (4,4,6,6-tetramethyl- 2,4,6,7-tetrahydro-5H-pyrrolo[3,4-c]pyridin-5-yl)oxidanyl gave polycyclic scaffolds condensed with a six-membered nitroxide