Internationalizing Canadian Higher Education through North-South Partnerships: A Critical Case Study of Policy Enactment and Programming Practices in Tanzania

The contemporary internationalization of higher education promotes the formation of North-South (N-S) partnerships to facilitate access to new research sites and opportunities for international programming. This study conceptualizes N-S partnerships as an extension of internationalization policy. In the current context of internationalization, there is a reliance on higher education to produce economic benefits to support national economic objectives. There are particular concerns, however, with a practice of N-S partnerships that are enacted in communities located in the Global South. Internationalization policy does not adhere to the principles of N-S partnership outlined in multilateral agreements and is increasingly focused on the production of economic returns from investment in partnerships projects. This research focuses on the enactment of a specific N-S ISL partnership in Tanzania to consider the effects of higher education internationalization on local communities. It raises critical concerns for a socially just practice of international partnership

Book Review - Educating children in conflict zones: Research, policy and practice for systemic change. A tribute to Jackie Kirk.

Educating children in conflict zones: Research, policy and practice for systemic change is a volume dedicated to the memory of Jackie Kirk, an educational researcher who was killed while working in Afghanistan. This collection of research articles is an excellent contribution to the field of education, conflict and development studies, Kirk\u27s area of expertise. The initial article is by Kirk and is a seminal piece in the field of education and conflict studies, and subsequent contributions by leading researchers in the field such as Lyn Davies, round out a volume that both adds to the growing knowledge of the contested role of education in conflict and lays out an agenda for future research

Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program

BackgroundDespite advances in asthma care, disparities persist. Black patients are disproportionally affected by asthma and also have poorer outcomes compared with white patients.ObjectiveWe sought to determine associations between black and white patients and asthma-related health care use, accounting for complex relationships.MethodsThis study was completed as part of the National Heart, Lung, and Blood Institute's Severe Asthma Research Program, a prospective observational cohort. Between November 2012 and February 2015, it enrolled 579 participants 6 years and older with 1 year of observation time and complete data. Inverse probability of treatment weighting was used to balance racial groups with respect to community and family socioeconomic variables and environmental exposure variables. The primary outcome was emergency department (ED) use for asthma. Secondary outcomes included inhaled corticosteroid use, outpatient physician's office visits for asthma, and asthma-related hospitalization.ResultsBlack patients had greater odds of ED use over 1 year (odds ratio, 2.19; 95% CI, 1.43-3.35) but also differed in the majority (>50%) of baseline variables measured. After statistical balancing of the racial groups, the difference between black and white patients with respect to ED use no longer reached the level of significance. Instead, in secondary analyses black patients were less likely to see an outpatient physician for asthma management (adjusted odds ratio, 0.57; 95% CI, 0.38-0.85).ConclusionsThe disparity in ED use was eliminated after consideration of multiple variables. Social and environmental policies and interventions tailored to black populations with a high burden of asthma are critical to reduction (or elimination) of these disparities

Evolution of the ancestral mammalian karyotype and syntenic regions

Decrypting the rearrangements that drive mammalian chromosome evolution is critical to understanding the molecular bases of speciation, adaptation, and disease susceptibility. Using 8 scaffolded and 26 chromosome-scale genome assemblies representing 23/26 mammal orders, we computationally reconstructed ancestral karyotypes and syntenic relationships at 16 nodes along the mammalian phylogeny. Three different reference genomes (human, sloth, and cattle) representing phylogenetically distinct mammalian superorders were used to assess reference bias in the reconstructed ancestral karyotypes and to expand the number of clades with reconstructed genomes. The mammalian ancestor likely had 19 pairs of autosomes, with nine of the smallest chromosomes shared with the common ancestor of all amniotes (three still conserved in extant mammals), demonstrating a striking conservation of synteny for ∼320 My of vertebrate evolution. The numbers and types of chromosome rearrangements were classified for transitions between the ancestral mammalian karyotype, descendent ancestors, and extant species. For example, 94 inversions, 16 fissions, and 14 fusions that occurred over 53 My differentiated the therian from the descendent eutherian ancestor. The highest breakpoint rate was observed between the mammalian and therian ancestors (3.9 breakpoints/My). Reconstructed mammalian ancestor chromosomes were found to have distinct evolutionary histories reflected in their rates and types of rearrangements. The distributions of genes, repetitive elements, topologically associating domains, and actively transcribed regions in multispecies homologous synteny blocks and evolutionary breakpoint regions indicate that purifying selection acted over millions of years of vertebrate evolution to maintain syntenic relationships of developmentally important genes and regulatory landscapes of gene-dense chromosomes