20 research outputs found
Evaluation of airborne particle emissions from commercial products containing carbon nanotubes
Transformation of the released asbestos, carbon fibers and carbon nanotubes from composite materials and the changes of their potential health impacts
Drugs for obstructive airway diseases: prescription patterns in two different health care settings in Piedmont (Italy)
Assessment of medication adherence and persistence among patients on antithyroid drug therapy in the ASL TO4 Regione Piemonte (Italy): a retrospective longitudinal cohort study
MANAGEMENT OF BENIGN PROSTATIC OBSTRUCTION-ASSOCIATED LOWER URINARY SYMPTOMS IN THE ASL TO4 REGIONE PIEMONTE (ITALY): PRESCRIPTION BEHAVIOUR AND TWELVE-MONTHS MEDICATION PERSISTENCE
Assessing medication adherence and persistence to statins in adults of the ASLTO4 (Piedmont, Italy)
Assessing medication adherence and persistence to antidiabetic drugs in naĂŻve patients from Piedmont (ASLTO4, Italy)
Assessing medication adherence to drugs for obstructive airway diseases (ATC R03): an observational study
Smoke exposure and cardio-metabolic profile in youth with type 1 diabetes
Abstract Background To evaluate the relationship between smoking and metabolic parameters in patients affected by type 1 diabetes (T1D). Patients and methods We enrolled 104 children and young adults (50 females and 54 males) with T1D (aged 16.4 ± 8.6 years). The subjects were divided into three groups according to their smoking habits: no smoking (NS), passive smoking (PS), active smoking (AS). The physical examination of the participants included nutritional status assessment by anthropometry and pubertal stage according to Marshall and Tanner as well as blood pressure measurement. In all patients, metabolic blood assays including fasting blood glucose, insulin, total cholesterol, high-density lipoprotein cholesterol, and triglycerides were measured. Insulin resistance was determined by glucose disposal rate (eGDR). Physical activity was also recorded. Results Significant differences in biochemical and functional parameters among the three groups were demonstrated, in particular for systolic (p = 0.002) and diastolic pressure (p = 0.02) and eGDR (p = 0.039). No differences in daily insulin dose (p = 0.75) and glycated hemoglobin (p = 0.39) were observed. AS group had significantly higher blood pressure (p < 0.05) and lower eGDR (p ≤ 0.001) compared to NS and PS. Significant difference was also detected between PS and NS in systolic and diastolic (p = 0.02) pressure and eGDR (p = 0.01). In a multivariable model adjusted for age, gender, BMI and physical activity, smoking habits did not maintain any independent association with metabolic parameters. Conclusion This is the first study in a Mediterranean population, looking at tobacco smoke and cardio-metabolic factors in youth with T1D. The relationship between smoking and unfavorable metabolic profile was demonstrated. On the basis of these findings, smoking tobacco should be considered an important modifiable risk factor for young patients with diabetes mellitus, highlighting the need for intensified smoking prevention and cessation programs