3 research outputs found
Lysis of Tumor-Cells by Cd3+4-8-16+ T-Cell Receptor Alpha-Beta-Clones, Regulated Via Cd3 and Cd16 Activation Sites, Recombinant Interleukin-2, and Interferon-Beta
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T cell receptor-engineered T cells to treat solid tumors: T cell processing toward optimal T cell fitness
Therapy with autologous T cells that have been gene-engineered to express chimeric antigen receptors (CAR) or T cell receptors (TCR) provides a feasible and broadly applicable treatment for cancer patients. In a clinical study in advanced renal cell carcinoma (RCC) patients with CAR T cells specific for carbonic anhydrase IX (CAIX)