Lidar Mapping of Near-Surface Aerosol Fields

Near-surface atmospheric measurements over urban or industrial areas aimed at assisting the air-quality monitoring attain increasing societal significance due to the strong and direct impact of aerosol pollutions in the low troposphere on the human health. In this chapter, we present experimental results on lidar mapping of aerosol fields over the city of Sofia (Bulgaria), its suburbs and adjacent towns and villages, obtained during an extensive 7-month experimental campaign in 2015. The measurements are conducted by scanning observation zones in horizontal and vertical directions using lidar systems developed at the Institute of Electronics, Bulgarian Academy of Sciences. Based on the aerosol backscattering profiles retrieved at different azimuth or elevation angles, two-dimensional color-coded sector maps of the near-surface aerosol density are obtained, overlaid on the topological map of the Sofia region. The analysis of the lidar maps shows good correlation between the aerosol density distribution and the locations of important sources of aerosol pollutions in the zones of observation, such as city streets with intense traffic, industrial facilities, densely populated residential districts, etc. The results reported demonstrate that aerosol lidar mapping could be regarded as an effective approach for accurate and reliable determination of the density, spatial distribution, and temporal dynamics of close-to-ground aerosols, covering broad urban areas. Possibilities of incorporating synergistically lidar mapping technologies into municipal air-quality monitoring systems are also discussed

Chapter Lidar Mapping of Near-Surface Aerosol Fields

Near-surface atmospheric measurements over urban or industrial areas aimed at assisting the air-quality monitoring attain increasing societal significance due to the strong and direct impact of aerosol pollutions in the low troposphere on the human health. In this chapter, we present experimental results on lidar mapping of aerosol fields over the city of Sofia (Bulgaria), its suburbs and adjacent towns and villages, obtained during an extensive 7-month experimental campaign in 2015. The measurements are conducted by scanning observation zones in horizontal and vertical directions using lidar systems developed at the Institute of Electronics, Bulgarian Academy of Sciences. Based on the aerosol backscattering profiles retrieved at different azimuth or elevation angles, two-dimensional color-coded sector maps of the near-surface aerosol density are obtained, overlaid on the topological map of the Sofia region. The analysis of the lidar maps shows good correlation between the aerosol density distribution and the locations of important sources of aerosol pollutions in the zones of observation, such as city streets with intense traffic, industrial facilities, densely populated residential districts, etc. The results reported demonstrate that aerosol lidar mapping could be regarded as an effective approach for accurate and reliable determination of the density, spatial distribution, and temporal dynamics of close-to-ground aerosols, covering broad urban areas. Possibilities of incorporating synergistically lidar mapping technologies into municipal air-quality monitoring systems are also discussed

Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance

Background: Insulin resistance plays a key role in the pathogenesis of polycystic ovarian syndrome (PCOS). One of the methods for correcting insulin resistance is using myo-inositol. Aim: The aim of the present study is to evaluate the effectiveness of myo-inositol alone or in combination with clomiphene citrate for (1) induction of ovulation and (2) pregnancy rate in anovulatory women with PCOS and proven insulin resistance. Patients and methods: This study included 50 anovulatory PCOS patients with insulin resistance. All of them received myo-inositolduring three spontaneous cycles. If patients remained anovulatory and/or no pregnancy was achieved, combination of myo-inositol and clomiphene citrate was used in the next three cycles. Ovulation and pregnancy rate, changes in body mass index (BMI) and homeostatic model assessment (HOMA) index and the rate of adverse events were assessed. Results: After myo-inositol treatment, ovulation was present in 29 women (61.7%) and 18 (38.3%) were resistant. Of the ovulatory women, 11 became pregnant (37.9%). Of the 18 myo-inositol resistant patients after clomiphene treatment, 13 (72.2%) ovulated. Of the 13 ovulatory women, 6 (42.6%) became pregnant. During follow-up, a reduction of body mass index and HOMA index was also observed. Conclusion: Myo-inositol treatment ameliorates insulin resistance and body weight, and improves ovarian activity in PCOS patients

Decreased Daily Melatonin Levels in Women with Systemic Lupus Erythematosus - A Short Report

Background: The neuroendocrine system is known to influence immunity, but the precise interactions between different hormones and autoimmune disorders remain obscure. Aims: The present study aimed to investigate the role of daily serum melatonin concentrations in the development of systemic lupus erythematosus (SLE) in women. Study Design: Case-control study Methods: One-hundred and eleven SLE female patients and 46 healthy women were included in the study. Daily serum melatonin levels were investigated in all participants. Results: SLE patients showed significantly lower daily melatonin levels in comparison to healthy women during the short photoperiod (17.75±7.13 pg/mL [16.05] vs. 21.63±6.60 pg/mL [20.10], p=0.012). Hormone concentrations were inversely related to the SLE activity index (SLEDAI) (r= -0.268, p=0.004), but they did not correlate to any particular American College Rheumatology (ACR) criterion (p>0.05 for all). Conclusion: Daily melatonin levels were decreased in women with systemic lupus erythematosus and correlated inversely to the activity of the autoimmune disease. Further studies are needed to clarify the importance of the pineal and extrapineal melatonin secretion in patients with systemic lupus erythematosus as well as the interrelations between hormones and autoimmunity