78 research outputs found

    Neutron beam test of CsI crystal for dark matter search

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    We have studied the response of Tl-doped and Na-doped CsI crystals to nuclear recoils and Îł\gamma's below 10 keV. The response of CsI crystals to nuclear recoil was studied with mono-energetic neutrons produced by the 3^3H(p,n)3^3He reaction. This was compared to the response to Compton electrons scattered by 662 keV Îł\gamma-ray. Pulse shape discrimination between the response to these Îł\gamma's and nuclear recoils was studied, and quality factors were estimated. The quenching factors for nuclear recoils were derived for both CsI(Na) and CsI(Tl) crystals.Comment: 21pages, 14figures, submitted to NIM

    Al0.52In0.48P avalanche photodiodes for soft X-ray spectroscopy

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    The performance of Al0.52In0.48P avalanche photodiodes was assessed as soft X-ray detectors at room temperature. The effect of the avalanche gain improved the energy resolution and an energy resolution (FWHM) of 682 eV is reported for 5.9 keV X-rays

    Submicroscopic deletion in cousins with Prader-Willi syndrome causes a grandmatrilineal inheritance pattern: effects of imprinting.

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    The Prader-Willi syndrome (PWS) critical region on 15q11–q13 is subject to imprinting. PWS becomes apparent when genes on the paternally inherited chromosome are not expressed. Familial PWS is rare. We report on a family in which a male and a female paternal first cousin both have PWS with cytogenetically normal karyotypes. Fluorescence in situ hybridization (FISH) analysis shows a submicroscopic deletion of SNRPN, but not the closely associated loci D15S10, D15S11, D15S63, and GABRB3. The cousins’ fathers and two paternal aunts have the same deletion and are clinically normal. The grandmother of the cousins is deceased and not available for study, and their grandfather is not deleted for SNRPN. DNA methylation analysis of D15S63 is consistent with an abnormality of the imprinting center associated with PWS. “Grandmatrilineal” inheritance occurs when a woman with deletion of an imprinted, paternally expressed gene is at risk of having affected grandchildren through her sons. In this case, PWS does not become evident as long as the deletion is passed through the matrilineal line. This represents a unique inheritance pattern due to imprinting
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