A prospective study on prevalence and characteristics of hematologic effects associated with subclinical hypothyroidism

Background: Distinctive types of iron deficiency have been accounted for patients with obvious hypothyroidism with a predominance of up to 47%. Regardless of the fact that vitamin B12, folic corrosive and iron fixations are ordinary, weakness that standardizes in light of thyroxine substitution is found in up to 25% of hypothyroid patients.Methods: Briefly, 50 women with SCH were enrolled in the study. Patients between 18 and 65 years old, with TSH levels more than 5.0 mIU/L, the patients selected has a history of hypothyroidism for more than a year and were on oral levothyroxine. A total of 50 participants were enrolled in the study. Blood samples were collected from 50 selected hypothyroid patients on the basis of a history of a hypothyroidism, persistent Anemia, of these patients all were females.Results: In present study 25 cases of age group 41-65 years  there were almost 10 patients having high thyroid stimulating factor (Tsh) that is more than (0.3-5.0U/Ml), Constitute to be 40% cases in this age category. Hence patients with high age may slower the response towards a levothyroxine hormone and hence have the high risk of developing anemia.Conclusions: Thyroid dysfunctions have an immediate impact on hemoglobin levels and these progressions should be considered in therapeutic consideration by medical practitioner

Modelling and simulation of fluid flow through a circular cylinder with high reynolds number: a COMSOL multiphysics study

In this study, we intend to investigate the steady-state and laminar �ow of a viscous �uid through a circular cylinder �xed between two parallel plates keeping the aspect ratio of 1 : 5 from cylinder radius to height of the channel. �e two-dimensional, in�compressible �uid �ow problem has been simulated using COMSOL Multiphysics 5.4 which implements �nite element’s procedure. �e �ow pattern will be investigated by using the Reynolds number from 100 to 1000. �e reattachment length formed at the back of the cylinder and drag force when the �uid comes to strike with the front surface of the cylinder is expressed in terms of Reynolds numbers. We propose to calculate the velocity and the pressure before and after the cylinder. For this purpose, two�line graphs before and after the cylinder will be drawn to check the impact of cylinder on both velocity and pressure. It was found that the percentage change in the velocity as well as pressure before to after the cylinder is changing their behaviours at Re � 700. �e study is important because the empirical equations between the vortex’s lengths formed along the cylinder using the linear regression process obtained in this study may be used for future implementatio

Effect of surfactant treatment on thermal stability and mechanical properties of CNT/polybenzoxazine nanocomposites

The mechanical and thermo-mechanical properties of polybenzoxazine nanocomposites containing multi-walled carbon nanotubes (MWCNTs) functionalized with surfactant are studied. The results are specifically compared with the corresponding properties of epoxy-based nanocomposites. The CNTs bring about significant improvements in flexural strength, flexural modulus, storage modulus and glass transition temperature, T g, of CNT/polybenzoxazine nanocomposites at the expense of impact fracture toughness. The surfactant treatment has a beneficial effect on the improvement of these properties, except the impact toughness, through enhanced CNT dispersion and interfacial interaction. The former four properties are in general higher for the CNT/polybenzoxazine nanocomposites than the epoxy counterparts, and vice versa for the impact toughness. The addition of CNTs has an ameliorating effect of lowering the coefficient of thermal expansion (CTE) of polybenzoxazine nanocomposites in both the regions below and above T g, whereas the reverse is true for the epoxy nanocomposites. This observation has a particular implication of exploiting the CNT/polybenzoxazine nanocomposites in applications requiring low shrinkage and accurate dimensional control. © 2012 Elsevier Ltd

Mechanical and thermal properties of Benzoxazine resin containing multiwalled carbon nanotubes

The mechanical and thermal properties of Benzoxazine epoxy system containing multiwalled carbon nanotubes (MWCNTs) are studied. The CNTs bring about significant improvements in flexural strength and modulus. The thermo-mechanical properties are characterized using the dynamic mechanical analysis (DMA), thermo-gravimetric analysis (TGA) and thermo-mechanical analysis (TMA). The results show that the storage modulus and glass transition temperature increase with increasing CNT content. The addition of CNTs has an ameliorating effect of lowering the coefficient of thermal expansion in both the regions below and above glass transition temperature. This observation has a particular implication on using the Benzoxazine epoxy nanocomposites requiring low shrinkage and accurate dimensional control. The mechanical and thermal properties of CNT-Benzoxazine nanocomposites are compared with those of typical epoxy nanocomposites containing similar CNTs

ACE I/D gene polymorphism in diabetic nephropathy: Clinical implications

Diabetic nephropathy (DN) is a major microvascular complication accounting for about 30% of End-Stage Renal Disease (ESRD) cases. An insertion/deletion (I/D) polymorphism of the gene encoding angiotensin-I converting enzyme (ACE) is reported to be a candidate gene predisposing to diabetic nephropathy. Accordingly, we investigated the ACE I/D gene polymorphism in 52 Type 2 diabetes mellitus (T2DM) cases suffering from nephropathy as assessed by 24 hrs urinary protein levels. 50 age and sex matched healthy subjects served as controls. ACE I/D genotyping was carried out by polymerase chain reaction (PCR) amplification using allele specific primers. The frequencies of ACE DD, ID and II genotypes in the diabetic nephropathy patients were 38.5% , 50% and 11.5% and in the control subjects, 22%, 38% and 40% respectively. There was an increase of 16.5% in the frequency of DD genotype in the patients compared to controls. The frequency of D allele in the patients was 63% which was found to be statistically significant (p< 0.05, Odds ratio=2.6) compared to 41% in the controls. These results indicate that Type 2 diabetic patients with D allele (those with DD & ID genotypes) have more than two fold risk of developing nephropathy. Clinical implications of ACE genotyping in planning for patient’s management have been discussed

Analysis of Power Law Fluids and the Heat Distribution on a Facing Surface of a Circular Cylinder Embedded in Rectangular Channel Fixed With Screen: A Finite Element&#x2019;s Analysis

The current article is an understanding of heat transfer and non-Newtonian fluid flow with implications of the power-law fluid on a facing surface of the circular cylinder embedded at the end of the channel containing the screen. The cylinder is fixed with an aspect ratio of 4:1 from height to the radius of the cylinder. The simulation for the fluid flow and heat transfer was obtained with variation of the angle of screen $\frac {\pi }{6}\le \theta \le \frac {\pi }{3}$ , Reynolds number 1000 &#x2264; Re &#x2264; 10, 000 and the power-law index $0.7\le n\le 1.3$ by solving two-dimensional incompressible Navier-Stokes equations and the energy equation with screen boundary condition and slip walls. The results will be in a good match with asymptotic solution given in the literature. The results are presented through graph plots for non-dimensional velocity, temperature, mean effective thermal conductivity, heat transfer coefficient, and the local Nusselt number on the front surface of the circular cylinder. It was found that the ratio between the input velocity to the present velocity on the surface of the circular cylinder remains consistent and reaches up to a maximum of 2.2&#x0025; and the process of heat transfer does not affect by the moving of the screen and clearly with the raise of power-law indexes the distribution of the heat transfer upsurges. On validation with two experimentally derived correlations, it was also found that the results obtained for the shear-thinning fluid are more precise than the numerically calculated results for Newtonian as well as shear-thickening cases. Finally, we suggest necessary measures to enrich the development of convection when observing with strong effects influenced by the screens or screen boundary conditions

Effect of Alkali Carbonates (Single, Binary, and Ternary) on Doped Ceria: A Composite Electrolyte for Low-Temperature Solid Oxide Fuel Cells

Samarium-doped ceria (SDC) carbonate has become an attractive electrolyte for fuel cells because of its remarkable ion conductivity and high performance. Different doped ceria-carbonate (single-carbonate SDC, binary-carbonate SDC, and ternary-carbonate SDC) electrolytes were synthesized by the coprecipitation/oxalate method, to optimize the electro-chemical performance. The structure; morphology; and thermal, optical, and surface properties have been studied using a variety of techniques. The X-ray diffraction results confirmed the successful incorporation of samarium into ceria as a crystalline structure and inclusion of carbonate, which is amorphous in nature. To analyze the conduction mechanism, direct current conductivity was measured in a H-2/O-2 atmosphere. Doped ceria-binary carbonate ((Li/Na)CO3-SDC) showed the best conductivity of 0.31 S cm(-1) and power density of 617 mW cm(-2), at 600 degrees C. The enhancement in the ionic conductivity and performance of the composites is due to the contribution of hybrid ions (O2-, H+). The crystallite size of the composites was in the range 21-41 nm. For the calculation of band gaps, optical absorption spectra of the synthesized powders were analyzed, and they showed a red shift with the band gap energy in the range 2.6-3.01 eV, when compared to that of pure ceria (3.20 eV)

Finite Element Analysis of Fluid Flow through the Screen Embedded between Parallel Plates with High Reynolds Numbers

This paper provides numerical estimation of Newtonian fluid flow past through rectangular channel fixed with screen movable from 10° to 45° by increasing the Reynolds number from 1000 to 10,000. The two-dimensional incompressible Navier Stokes equations are worked out making use of the popular software COMSOL MultiPhysics version 5.4 which implements the Galerkin’s least square scheme to discretize the governing set of equations into algebraic form. In addition, the screen boundary condition with resistance coefficient (2.2) along with resistance coefficient 0.78 is implemented along with slip boundary conditions applied on the wall. We engaged to find and observe the relationship between the optimum velocity, drag force applied by the screen, and pressure occurred in the channel with increasing Reynolds number. Because of the linear relationship between the optimum velocities and the Reynolds number, applying the linear regression method, we will estimate the linear equation so that future prediction and judgment can be done. The validity of results is doing with the asymptomatic solution for stream-wise velocity at the outlet of the channel with screens available in the literature. A nondimensional quantity, i.e., ratio from local to global Reynolds number Rex/Re, is introduced which found stable and varies from -0.5 to 0.5 for the whole problem. Thus, we are in the position to express the general pattern of the velocity of the particles as well as the pressure on the line passing through the middle of the channel and depart some final conclusion at the end

Finite Element Least Square Technique for Newtonian Fluid Flow through a Semicircular Cylinder of Recirculating Region via COMSOL Multiphysics

This article aims to study Newtonian fluid flow modeling and simulation through a rectangular channel embedded in a semicircular cylinder with the range of Reynolds number from 100 to 1500. The fluid is considered as laminar and Newtonian, and the problem is time independent. A numerical procedure of finite element’s least Square technique is implemented through COMSOL multiphysics 5.4. The problem is validated through asymptotic solution governed through the screen boundary condition. The vortex length of the recirculating region formed at the back of the cylinder and orientation of velocity field and pressure will be discussed by three horizontal and four vertical lines along the recirculating region in terms of Reynolds number. It was found that the two vortices of unequal size have appeared and the lengths of these vortices are increased with the increase Reynolds number. Also, the empirical equations through the linear regression procedure were determined for those vortices. The orientation of the velocity magnitude as well as pressure along the lines passing through the center of upper and lower vortices are the same