2,141 research outputs found
Commercial Sexual Exploitation of Teens
This research explores whether commercially sexually exploited children (CSEC) abuse drugs or face greater histories of abuse than their delinquent peers. This research will evaluate whether girls who are CSEC victims experience more abuse of drugs or experience more physical, emotional, or sexual abuse. The study also explores whether CSEC victims witnessed more abuse than non-CSEC victims. A survey of needs and issues facing delinquent girls was given to 130 girls between the ages of 13 to 18. Questions asked about their drug use, abuse history, and whether they witnessed abuse. This research found that many girls who are CSEC victims experience and witnessed more abuse than non-CSEC victims. The results also showed that CSEC victims and non-CSEC delinquent peers showed no significant difference in drug use
Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives
Background: Many polyhydroxylated piperidines are inhibitors of the oligosaccharide processing
enzymes, glycosidases and glycosyltransferases. Aza-C-linked disaccharide mimetics are compounds
in which saturated polyhydroxylated nitrogen and oxygen heterocycles are linked by an all-carbon
tether. The saturated oxygen heterocycle has the potential to mimic the departing sugar in a
glycosidase-catalysed reaction and aza-C-linked disaccharide mimetics may, therefore, be more
potent inhibitors of these enzymes.
Results: The scope, limitations and diastereoselectivity of the dihydroxylation of stereoisomeric
2-butyl-1-(toluene-4-sulfonyl)-1,2,3,6-tetrahydro-pyridin-3-ols is discussed. In the absence of a 6-
substituent on the piperidine ring, the Upjohn (cat. OsO4, NMO, acetone-water) and Donohoe
(OsO4, TMEDA, CH2Cl2) conditions allow complementary diastereoselective functionalisation of
the alkene of the (2R*,3R*) diastereoisomer. However, in the presence of a 6-substituent, the
reaction is largely controlled by steric effects with both reagents. The most synthetically useful
protocols were exploited in the two-directional synthesis of aza-C-linked disaccharide analogues.
A two-directional oxidative ring expansion was used to prepare bis-enones such as (2R,6S,2'S)-6-
methoxy-2-(6-methoxy-3-oxo-3,6-dihydro-2H-pyran-2-ylmethyl)-1-(toluene-4-sulfonyl)-1,6-
dihydro-2H-pyridin-3-one from the corresponding difuran. Selective substitution of its N,O acetal
was possible. The stereochemical outcome of a two-directional Luche reduction step was different
in the two heterocyclic rings, and depended on the conformation of the ring. Finally, twodirectional
diastereoselective dihydroxylation yielded seven different aza-C-linked disaccharide
analogues.
Conclusion: A two-directional approach may be exploited in the synthesis of aza-C-linked
disaccharide mimetics. Unlike previous approaches to similar molecules, neither of the heterocyclic
rings is directly derived from a sugar, allowing mimetics with unusual configurations to be prepared.
The work demonstrates that highly unsymmetrical molecules may be prepared using a two
directional approach. The deprotected compounds may have potential as inhibitors of
oligosaccharide-processing enzymes and as tools in chemical genetic investigations
Police Responses to Domestic Violence and Public Perception
Domestic violence, also known as, intimate partner violence (IPV), has become an epidemic in the United States. This research is intended to explain the types of IPV, describe the effects of severe IPV, look at the change in public perceptions of IPV situations, and explore the police responses to such situations. Students at UNLV participated in the “Police Responses to Calls for Service” survey, that was created to determine the public’s level of awareness of IPV situations and whether that awareness increases support for police policies in responding to intimate partner violence calls
An Examination of Attitudes Toward Sexualized Advertising in Las Vegas
This study explores the attitudes of college-level criminal justice students as to their perception of sexualized advertising in Las Vegas, and if these attitudes have any correlation with the participant’s length of residency. The study also correlates college-level student’s attitudes toward sexualized advertising and how religious they rate themselves. Female participants who lived in Las Vegas for 5 years or more on average agreed advertisements in Las Vegas are too sexualized. In contrast, female participants who were either born in Las Vegas or lived there less than 5 years neither agreed nor disagreed that advertising was too sexualized. As for the males, only those who lived in Las Vegas for 5 to 9 years on average agreed that advertisements in Las Vegas are too sexualized. Those participants who considered themselves very religious on average agreed that advertising in Las Vegas were too sexualized
Information Security Surveys: A Review of the Methodologies, the Critics and a Pragmatic Approach to their Purposes and Usage
Each year the latest information security surveys are released to the computing and business communities. Often their findings and their methodologies are subject to criticism from the information security community, professional bodies and others in the profession. This paper looks at the viewpoints of both the producers and the critics of the surveys. The criticisms cover such issues as the methodologies, the response rates, the experience of the respondents, the design of the questions and the interpretation of the results. This paper looks at these issues and discusses the validity of these criticisms, the impact of the surveys and their value to business and government. It compares the methodologies of some of the largest local and international players in the area. It discusses the issues arising from flawed methodologies, inaccurate information and poor processes, including the perceived lack of integrity and the accuracy of the measurements and methodologies. Despite the strong criticism a middle ground emerged. Data input by the participants, whether accurate or not, may be highly subjective and influenced by their environment and business profile. Furthermore, security at a business level may be extremely complex, the governance principles dictating that the organisation profile, management ideologies and core business values must be accounted for and balanced even for IT. The paper also considers the interpretation of the results and how they may be influenced by current and future products and the vendors of those products. Finally the paper takes a closer look at the use of the surveys in a business context and attempts to show that if constructively used, these surveys can be powerful metric tools used in driving information security strategies in spite of their perceived deficiencies
Mapping food access and related risk factors in forecasting social disorder
Includes bibliographical references
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Space-Based Capstone: Public-Private-Academic Partnership in the Making
The Electronic Systems Engineering Technology (ESET) Program at Texas A&M University provides a recognized undergraduate program with an emphasis in electronics, communication, embedded systems, testing, instrumentation and control systems. The program combines engineering and industrial knowledge and methods to develop, design, and implement new innovative products through a two-semester long Senior Capstone Project.
Capstone is designed to prepare future engineers by bridging the gap between the classroom and industry. Students are required to form teams of two to six members which allows them to develop the skills necessary to succeed in a diverse industry setting. Each team is required to use their knowledge and skills to design, develop, document, and deliver a real-world project equivalent to the assignments they will soon receive as professional engineers.
Following NASA’s approval for funding the development of a research facility named Hermes, a Capstone team, named Microgravity Automated Research Systems (MARS), was sponsored by T STAR, a local space commercialization company, to develop the electronics portion of the facility. Hermes will reside on the International Space Station for five years in the hopes of streamlining the development of experiments that require extended periods of time in microgravity environments.
The Hermes facility will host and manage up to four experiments at a time while allowing for the downlink of experiment data to an Earth station, and the uplink of commands to change experiment parameters. Experiments will adhere to a power budget and communication standard established by MARS so that experiments can be swapped out during the facility’s lifetime. MARS will work with the Mobile Integrated Solutions Laboratory (MISL), an undergraduate applied research lab, in order to prepare them to maintain support for Hermes in the future.Cockrell School of Engineerin
Changing Awareness of Human Trafficking
The issue of human trafficking has received increased attention since the Trafficking Victims Protection Act was enacted in 2000. We assume that awareness is growing in the United States but this has not been tested. The current study measures increases in awareness about the issue of trafficking. Nearly 400 students were polled about their awareness in the spring of 2007. Attitudes towards government responses, awareness of the issue and support for victims were surveyed. The study was replicated 5 years later with over 500 new participants. This paper will analyze changes in awareness over time. Gender differences will also be presented. Attitudes towards trafficking will be considered in light of the assumptions underlying the TVPA and its reauthorizations
Crystal structure of 2-methyl-3-nitroÂbenzoic anhydride
The title molecule, C16H12N2O7, lies on a twofold rotation axis which bisects the central O atom. The dihedral angle between two symmetry-related benzene rings is 48.54 (9). In the crystal, molecules are linked by weak C—H O hydrogen bonds which generate C(13) chains running parallel to [311]
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