Harnessing the power of volunteers, the internet and Google Earth to collect and validate global spatial information using Geo-Wiki

Information about land cover and land use is needed for a wide range of applications such as nature protection and biodiversity, forest and water management, urban and transport planning, natural hazard prevention and mitigation, monitoring of agricultural policies and economic land use modelling. A number of different remotely-sensed global land cover products are available but studies have shown that there are large spatial discrepancies between these different products when compared. To address this issue of land cover uncertainty, a tool called Geo-Wiki was developed, which integrates online and mobile applications, high resolution satellite imagery available from Google Earth, and data collection through crowdsourcing as a mechanism for validating and improving globally relevant spatial information on land cover and land use. Through its growing network of volunteers and a number of successful data collection campaigns, almost 5 million samples of land cover and land use have been collected at many locations around the globe. This paper provides an overview of the main features of Geo-Wiki, and then using a series of examples, illustrates how the crowdsourced data collected through Geo-Wiki have been used to improve information on land cover and land use

Resting State Brain Network Disturbances Related to Hypomania and Depression in Medication-Free Bipolar Disorder

Research on resting functional brain networks in bipolar disorder (BP) has been unable to differentiate between disturbances related to mania or depression, which is necessary to understand the mechanisms leading to each state. Past research has also been unable to elucidate the impact of BP-related network disturbances on the organizational properties of the brain (eg, communication efficiency). Thus, the present work sought to isolate network disturbances related to BP, fractionate these into components associated with manic and depressive symptoms, and characterize the impact of disturbances on network function. Graph theory was used to analyze resting functional magnetic resonance imaging data from 60 medication-free patients meeting the criteria for BP and either a current hypomanic (n=30) or depressed (n=30) episode and 30 closely age/sex-matched healthy controls. Correction for multiple comparisons was carried out. Compared with controls, BP patients evidenced hyperconnectivity in a network involving right amygdala. Fractionation revealed that (hypo)manic symptoms were associated with hyperconnectivity in an overlapping network and disruptions in the brain's ‘small-world' network organization. Depressive symptoms predicted hyperconnectivity in a network involving orbitofrontal cortex along with a less resilient global network organization. Findings provide deeper insight into the differential pathophysiological processes associated with hypomania and depression, along with the particular impact these differential processes have on network function

Evaluating Patient-reported Outcomes after Bilateral Reduction Mammoplasty: A Comparison of Reduction Techniques at a University Hospital

Background:. Macromastia, defined as the abnormal enlargement of breasts, burdens individuals physically and psychologically, impacting their daily lives beyond aesthetics. Reduction mammoplasty offers relief by restoring proportional breast volume and appropriate contour. Surgical success relies on choosing a suitable individualized operative technique tailored to the patient’s presentation and postoperative goals. This study examines postoperative, patient-reported outcomes across different reduction techniques to gauge the impact of reduction technique on overall patient perspective of aesthetic and functional satisfaction. Methods:. A retrospective review identified reduction mammoplasty patients by a single surgeon between 2018 and 2022. Exclusion criteria included augmentation-related or cancer reconstructive procedures. Phone interviews were conducted using a survey adapted from BREAST-Q to assess postoperative outcomes in patients. Data analysis included Pearson chi-square test in STATA 16.1. Results:. Among 155 patients identified, 64 completed the survey. Average postsurgical interval was 24 months postoperative. After stratifying patients by operative technique, there was no significant difference in postoperative satisfaction among the cohorts with regard to nipple and breast appearance, sensation, symmetry, or shape. Conclusions:. This study highlights no significant disparity in perceived aesthetic or functional outcomes among different reduction mammoplasty techniques. Personalized considerations, such as patient factors, surgical expertise, and anatomical specifics, should guide technique selection, emphasizing individualized approaches over presumed superior methods for optimal results