Effect of hyoscine butylbromide first stage of labour in multiparus women

Background: Prolonged labor is one of the most important risk factors for perinatal compromise and, if caused by obstructed labor, it carries the risk of uterine rupture, postpartum hemorrhage (PPH), puerperal sepsis, and maternal death. Objective: To determine whether or not hyoscine butylbromide shortens the stages of labor, without an increase in maternal or neonatal complications. Method: In single-blinded randomized clinical trial study , 188 multiparas women in active phase of labor who were admitted to Shahid Sadoughi Hospital from October 2006 to April 2007 in Yazd - Iran , were evaluated . They were divided hyoscine group (n = 94) received 20mg (1ml) of hyoscine and control group (n = 94) received 1 ml of normal saline was given as placebo, intravenously. The effects of hyoscine in shortening labor time; and neonatal Apgar score was compared. Results: Duration of the first (mean± SD: 186.8 ± 125.6 minutes vs. 260.4 ± 120.9 minutes, p= 0.00 1) and second stage of labor (mean± SD: 20.0 ± 8.1minutes vs. 25.8 ± 9.4 minutes, p= 0.03) was shorter in hyoscine group. Frequency of cesarean section and mean of neonatal Apgar score at minutes of one and 5 were not different in both groups. No serious adverse events were seen in the two groups. Conclusion: Injection of hyoscine in active phase of labor can be effective in shortening of labor without any adverse effect on mother and fetus

Effect of hyoscine butylbromide first stage of labour in multiparus women

BACKGROUND: Prolonged labor is one of the most important risk factors for perinatal compromise and, if caused by obstructed labor, it carries the risk of uterine rupture, postpartum hemorrhage (PPH), puerperal sepsis, and maternal death. OBJECTIVE: To determine whether or not hyoscine butylbromide shortens the stages of labor, without an increase in maternal or neonatal complications. METHOD: In single-blinded randomized clinical trial study, 188 multiparas women in active phase of labor who were admitted to Shahid Sadoughi Hospital from October 2006 to April 2007 in Yazd - Iran, were evaluated. They were divided hyoscine group (n = 94) received 20mg (1ml) of hyoscine and control group (n = 94) received 1 ml of normal saline was given as placebo, intravenously. The effects of hyoscine in shortening labor time; and neonatal Apgar score was compared. RESULTS: Duration of the first (mean± SD: 186.8 ± 125.6 minutes vs. 260.4 ± 120.9 minutes, p= 0.00 1) and second stage of labor (mean± SD: 20.0 ± 8.1minutes vs. 25.8 ± 9.4 minutes, p= 0.03) was shorter in hyoscine group. Frequency of cesarean section and mean of neonatal Apgar score at minutes of one and 5 were not different in both groups. No serious adverse events were seen in the two groups. CONCLUSION: Injection of hyoscine in active phase of labor can be effective in shortening of labor without any adverse effect on mother and fetus

Comparison the Effect of Student-Based Group Discussion and Lecture Methods Teaching on Midwifery Student\'s Learning Level

Aims: True learning needs the utilization of proper teaching methods leading to students’ interests in the learning activities to gain useful learning experiences. Therefore, it is needed to reform the traditional teaching methods and to use new student-focused methods by the educational systems.  The aim of this study was to compare the effects of the student-focused group discussion method and lecture method on the learning level in the Midwifery students. Materials & Methods: In the semi-experimental study, 72 third-semester Midwifery bachelor students of Islamic Azad University, Gorgan Branch, were selected via census method to participate in the theoretical clinical pregnancy course presented as lecture and group discussion methods in 2014. The final test was done after the end of the training courses. And, material durability test was done 8 weeks after the end of the course sessions. Data was analyzed, using SPSS 16 software and Wilcoxon Non-parametric Test. Findings: There was a significant difference between the mean scores of all the sessions conducted through lecture method (45.00±8.00) and group discussion method (57.00±10.00; p=0.0001). There was a significant difference in the material durability after 8 weeks between the mean scores of lecture (24.50±13.90) and group discussion (35.10±13.10) methods (p=0.0001). Conclusion: Standard student-focused group discussion training affects the midwifery students’ learning more than the lecture method does and there is higher information durability. &nbsp

Scaffold percolative efficiency: in vitro evaluation of the structural criterion for electrospun mats

Fibrous scaffolds of engineered structures can be chosen as promising porous environments when an approved criterion validates their applicability for a specific medical purpose. For such biomaterials, this paper sought to investigate various structural characteristics in order to determine whether they are appropriate descriptors. A number of poly(3-hydroxybutyrate) scaffolds were electrospun; each of which possessed a distinguished architecture when their material and processing conditions were altered. Subsequent culture of mouse fibroblast cells (L929) was carried out to evaluate the cells viability on each scaffold after their attachment for 24 h and proliferation for 48 and 72 h. The scaffolds’ porosity, pores number, pores size and distribution were quantified and none could establish a relationship with the viability results. Virtual reconstruction of the mats introduced an authentic criterion, “Scaffold Percolative Efficiency” (SPE), with which the above descriptors were addressed collectively. It was hypothesized to be able to quantify the efficacy of fibrous scaffolds by considering the integration of porosity and interconnectivity of the pores. There was a correlation of 80% as a good agreement between the SPE values and the spectrophotometer absorbance of viable cells; a viability of more than 350% in comparison to that of the controls