Unfolded protein response to the hypercholesterolemia induced endoplasmic reticulum stress in atherosclerosis

40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life -- July 04-09, 2015 -- Berlin, GermanyWOS: 000362570602023…Federation of European Biochemical Societie

Effects of ridge and conventional tillage systems on soil properties and cotton growth

Cotton (Gossypium hirsutum L.) seeds are susceptible to low temperature and excess moisture in soil during seed emergence in years with high rainfall and low temperature in spring. Therefore, a two-year field experiment was carried out to evaluate effects of ridge tillage formed in autumn (RT-I), ridge tillage formed about a month before planting (RT-II) and flat conventional tillage (CT) cultivation systems on physical properties of soil and cotton growth. The RT-I and RT-II resulted in higher soil temperature and lower soil penetration resistance than CT at all depths. The RT-II gave highest emergence, earliest maturity and greatest seed cotton yield. In conclusion, ridge tillage formed a month before planting may be considered a good agronomic practice because it can provide favorable physical conditions in soil, while also improving growth and yield of cotton under weather conditions in spring in South East Anatolia Region of Turkey

Effects of Different Stress Conditions on Apoptosis, Proteasome Activity and Exosome Cell Death Pathways in Hepatocellular Carcinoma Cells

In both healthy cells and cancer cells a number of different cellular responses influence the progress of cancer. In this study, we have investigated the effect of stress conditions on human hepatocyte cancer cells. Different concentrations of hydrogen peroxide, quercetin and N-acetyl cysteine were used to induce the acute cell stress. We have detected apoptosis, measured proteasome activity and performed a cell death array in both treated and control cells. Treatment of human hepatocyte cancer cells with hydrogen peroxide and quercetin resulted in decreased cell viability and increased apoptosis. On the other hand, proteasome activity was increased with hydrogen peroxide treatment but decreased with quercetin. N-acetyl cysteine supported cell viability and increased proteasome activity. In conclusion, cell death related genes were affected in quite different manner following hydrogen peroxide, quercetin and N-acetyl cysteine treatments