The Impact of the Teacher’s Personality on the Motivation of Learning the English Language Among Governmental School Students in Saudi Arabia

The current study aimed to identify the impact of the teachers personality on the motivation of learning English among government school students in the city of Abha, Saudi Arabia. The descriptive correlative method was used, and two questionnaires were designed to collect the data. They were distributed electronically, and the study targeted a sample of English language teachers in public secondary schools in Abha, and a sample of high school students in Abha, who were chosen randomly in a simple way. The results of the study showed that English language teachers have personal characteristics that qualify them to teach in high government schools, with an average of (3.6918), which is considered as a highly - approved degree, and that students have a motivation to learn English with an average of (3.7828), which means they scored a high degree of approval. The results also showed the effect of the teachers personality on the motivation of students towards learning English. The results also showed that it is possible to predict the motivation of learning English through the teachers personality

The Use of Advanced Spectral Imaging to Reveal Nanoparticle Identity in Biological Samples

Nanoparticles (NPs) have been used in drug delivery therapies, medical diagnostic strategies, and as current Covid-19 vaccine carriers. Many microscope-based imaging systems have been introduced to facilitate detection and visualization of NPs. Unfortunately, none can differentiate the core and the shell of NPs. Spectral imaging has been used to distinguish a drug molecule and its metabolite. We have recently integrated this technology to a resolution of 9 nm by using artificial intelligence-driven analyses. Such a resolution allowed us to collect many robust datapoints for each pixel of an image. Our analyses could recognize 45 spectral points within a pixel to detect unlabeled Ag-NPs and Au-NPs in single live cells and tissues (liver, heart, spleen and kidneys). The improved resolution and software provided a more specific fingerprinting for each single molecule, allowing simultaneous analyses of 990 complex interactions from the 45 points for each molecule within a pixel of an image. This in turn allowed us to detect surface-functionalization of Ag-NPs to distinguish the core from the shell of Ag-NPs for the first time. Our studies were validated using various laborious and time-consuming conventional techniques. We propose that spectral imaging has tremendous potential to study NP localization and identification in biological samples at a high temporal and spatial resolution, based primarily on spectral identity information

The Challenges of Psychological Adjustment for International Students: A Critical Analysis of Coping Mechanisms and Support Services

This paper critically analyzes the challenges of psychological adjustment faced by international students and explores coping mechanisms and support services that can help them overcome these challenges. The essay first introduces the background information on international students and highlights the importance of psychological adjustment for their well-being and academic success. The challenges of psychological adjustment, including cultural, academic, social adjustment, and language barrier, are discussed in detail. The essay then explores coping mechanisms, including problem-focused coping, emotion-focused coping, seeking social support, and cultural adjustment programs, and the support services, including counseling services and international student services, that can help international students adjust to their new environment. Finally, the essay evaluates the effectiveness of these coping mechanisms and support services, emphasizing the importance of cultural competence in providing effective support services. This essay has practical implications for higher education institutions in providing tailored support to international students and highlights the need for future research to explore the effectiveness of coping mechanisms and support services for different groups of international students and the impact of the COVID-19 pandemic on their psychological adjustment

The Effect of Social Isolation on the Mental Health of International Students

This paper looks into how social isolation affects international college students mental health. An increase in international students studying at colleges and universities abroad can be attributed to increased global mobility over the previous few decades. Because of this, these students struggle in certain ways to fit into their new academic and social surroundings. Among these difficulties, social isolation among overseas students has been recognized as a major issue. This essay will investigate how social isolation affects the mental health of international college students by drawing on existing studies. The various types of social isolation will be covered in the essay along with how they may affect mental health. It will also be looked at whether factors like linguistic difficulties, cultural shock, prejudice, and discrimination contribute to social isolation among overseas students. In light of the hazards to mental health posed by social isolation among international students, this presentation will offer some potential solutions. The findings of the inquiry will be utilized to create solutions that can assist overseas students in reducing the detrimental impacts of social isolation on their mental health. Compared to other groups, college students’ mental health has not been adequately researched, even though social isolation can be an emotionally and mentally damaging experience. The paper will focus on the various mental health impacts that international college students experience such as depression, anxiety, and long-term psychological harm. An analysis of existing literature on the topic, interviews with international college students, and the mental health resources available to this population are also discussed. The main findings of the research show that international college students living in a foreign country experience significant levels of social isolation due to language barriers and cultural differences

ROLE OF THE PHYSICAL ACTIVITY IN THE IMPROVEMENT OF CARDIAC MEASURES AND DECLINING OF COMORBIDITIES.

Background: Regular physical activity (PA) can prevent many non-communicable diseases, such as cardiovascular disease (CVD) and diabetes mellitus (DM). The present study aimed to assess the health benefits of physical activities including blood pressure and comorbid conditions. Methodology: This is a prospective cohort case-control study that recruited 300 Saudi volunteers living in the city ofHail, Northern Saudi Arabia. Results: Out of 300 participants 155(51.7%) were males and 145 (48.3%) were females. There were 111(37%) participants committed to regular physical activity and the remaining 189(63%) without a defined commitment to physical activity (Uncommitted). Among 111 persons who claimed a commitment to regular physical activity (committed), 61(55%) were males and 50(45%) were females. The majority of committed individuals were at the age group 21-25 years followed by age group 26-30 and 31-35 years representing 32, 30, and 20 persons, respectively. The physical activity was highly practiced at the age range 21-30 years and this was found to be statistically significant P < 0.001. Conclusion: There is a low prevalence of physical activity in Hail region, particularly among females, which necessitates the suggestion of appropriate awareness programs. Younger and elder populations are in much need to be targeted with PA awareness programs

Classifying Drug Resistance in the NCI60 Cancer Cell Lines Based on the mRNA Expression Levels of the 48 ABC Transporters

Poster for the 2014 MCBIOS Conference. This poster discusses classifying drug resistance in the NCI60 cancer cell lines based on the mRNA expression levels of the 48 ABC transporters

Measuring the impact of suspending Umrah, a global mass gathering in Saudi Arabia on the COVID‑19 pandemic

This article uses a stratified SEIR epidemic model to evaluate the impact of Umrah, a global Muslim pilgrimage to Mecca, on the spread of the COVID-19 pandemic during the month of Ramadan, the peak of the Umrah season. The analyses provide insights into the effects of global mass gatherings on the progression of the COVID-19 pandemic locally and globally

Examining bedtime procrastination, study engagement, and studyholism in undergraduate students, and their association with insomnia

IntroductionCompulsive overstudying, known as studyholism, is an emerging behavioral addiction. In this study, we examine the prevalence of, and the relationships between, insomnia, study engagement, studyholism, bedtime procrastination among undergraduate students.MethodsThe Studyholism (SI-10), Athens Insomnia (AIS), and bedtime procrastination scales were administered to a convenience sample of 495 university students.ResultsOur findings indicate that the prevalence of insomnia was 75.31%, high studyholism was found in 15.31% of the sample, and increased study engagement was detected in 16.94%. Gender differences analysis revealed that females reported higher studyholism and bedtime procrastination than males. Fifth-year students had higher levels of studyholism than internship (p &lt; 0.001), first-year (p &lt; 0.01), and sixth-year students (p &lt; 0.05). Insomnia was positively related to studyholism and bedtime procrastination. Furthermore, insomnia can be positively predicted by studyholism and bedtime procrastination. Participants with a medium level of studyholism were twice as likely to experience insomnia as those with a low level. Studyholics were six times more susceptible to insomnia than students with low studyholism levels. Compared to individuals with low bedtime procrastination levels, those with medium and high bedtime procrastination were twice as likely to report insomnia.ConclusionOur study highlights the interplay between insomnia, studyholism, and bedtime procrastination. Further, the findings indicate the need to increase awareness of insomnia

Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents

Three new series of paracyclophanyl-dihydronaphtho[2,3-d]thiazoles and paracyclophanyl-thiazolium bromides were designed, synthesized, and characterized by their spectroscopic data, along with X-ray analysis. One-dose assay results of anticancer activity indicated that 3a–e had the highest ability to inhibit the proliferation of different cancer cell lines. Moreover, the hybrids 3c–e were selected for five-dose analyses to demonstrate a broad spectrum of antitumor activity without apparent selectivity. Interestingly, series I compounds (Z)-N-substituted-4,9-dihydronaphtho[2,3-d]thiazol-3(2H)-yl)-4′-[2.2]paracyclophanylamide) that are carrying 1,4-dihydronaphthoquinone were more active as antiproliferative agents than their naphthalene-containing congeners (series II: substituted 2-(4′-[2.2]paracyclophanyl)hydrazinyl)-4-(naphth-2-yl)-thiazol-3-ium bromide hybrids) and (series III: 3-(4′-[2.2]paracyclophanyl)amido-2-(cyclopropylamino)-4-(naphth-2-yl)thiazol-3-ium bromide) toward the SK-MEL-5 melanoma cell line. Further antiproliferation investigations of 3c and 3e on the healthy, normal unaffected SK-MEL-5 cell line indicated their relative safety. Compound 3c showed an inhibition of eight isoforms of cyclin-dependent kinases (CDK); however, it exhibited the lowest IC50 of 54.8 nM on CDK1 in comparison to Dinaciclib as a reference. Additionally, compound 3c revealed a remarkable downregulation of phospho-Tyr15 with a level (7.45 pg/mL) close to the reference. 3c mainly showed cell cycle arrest in the pre-G1 and G2/M phases upon analysis of the SK-MEL-5 cell line. The sequential caspase-3 assay for 3c indicated a remarkable overexpression level. Finally, a molecular docking study was adopted to elucidate the binding mode and interactions of the target compounds with CDK1