Patients' characteristics of the smear-negative PTB suspects included in the prospective study.

a<p>. BMI: body mass index.</p>b<p>. Malnourished: BMI<18.5.</p

LAM, smear microscopy, Xpert and MTB culture results.

<p>LAM, smear microscopy, Xpert and MTB culture results.</p

Diagnostic yield of different diagnostic algorithms with no LAM and with LAM among TB confirmed patients from various study subgroups.

<p>Diagnostic yield of different diagnostic algorithms with no LAM and with LAM among TB confirmed patients from various study subgroups.</p

Diagnostic and treatment pathway of 474 patients with TB symptoms.

<p>Diagnostic and treatment pathway of 474 patients with TB symptoms.</p

Patients’ characteristics of the 474 HIV-positive patients with TB symptoms included.

<p>Patients’ characteristics of the 474 HIV-positive patients with TB symptoms included.</p

Diagnostic algorithm for smear-negative TB suspects (prospective study).

<p>Diagnostic algorithm for smear-negative TB suspects (prospective study).</p

Diagnostic yield of different diagnostic algorithms with no LAM and with LAM in 156 TB confirmed patients.

<p>Diagnostic yield of different diagnostic algorithms with no LAM and with LAM in 156 TB confirmed patients.</p

Culture results of smear-negative PTB suspects, prospective study.

a<p>. In 2 patients LJ was negative and TLA was not performed.</p

Factors associated with overtreatment when the diagnostic algorithm without culture was used (prospective study, N = 303).

<p>Factors associated with overtreatment when the diagnostic algorithm without culture was used (prospective study, N = 303).</p

Clinical-radiological algorithm ROC curves.

<p>ROC curve for the clinical-radiological smear-negative diagnostic algorithm without culture in the prospective study (A) and in the retrospective analysis of program data (B).</p