Associations between high affinity^‡ SSRI use and RV measures in limited and adjusted models, stratified by sex for RV mass and RVEDV.

<p>*Adjusted for age, sex, race/ethnicity, height, weight, and level of education.</p>†<p>Adjusted for age, sex, race/ethnicity, height, weight, level of education, depression (Center for Epidemiologic Studies Depression-Scale (CES-D) ≥16), smoking (status and pack-years), hypertension, systolic and diastolic blood pressure, cholesterol, low-density lipoprotein levels, triglycerides, and statin use.</p>‡<p>Fluoxetine, fluvoxamine, paroxetine, and sertraline.</p

Associations between SSRI use and RV measures in limited and adjusted models, stratified by sex for RV mass and RVEDV.

<p>*Adjusted for age, sex, race/ethnicity, height, weight, and level of education.</p>†<p>Adjusted for age, sex, race/ethnicity, height, weight, level of education, depression (Center for Epidemiologic Studies.</p><p>Depression-Scale (CES-D) ≥16), smoking (status and pack-years), hypertension, systolic and diastolic blood pressure, cholesterol, low-density lipoprotein levels, triglycerides, and statin use.</p

Characteristics of the study sample and of those participants excluded.

<p>Data shown as mean ± standard deviation or %. Percentages may not add to one because of rounding.</p><p>*Citalopram.</p>†<p>Fluoxetine, fluvoxamine, paroxetine, and sertraline.</p>‡<p>Includes atypical (bupropion), monoamine oxidase inhibitors, tetracyclic (mirtazapine), and serotonin antagonist and reuptake inhibitor (trazodone and nefazodone) antidepressants.</p

Study sample.

<p>MESA: Multi-Ethnic Study of Atherosclerosis; MRI: magnetic resonance imaging; LV: left ventricle; RV: right ventricle.</p