Diplomirani studenti na Odsjeku za informacijske znanosti Filozofskog fakulteta Sveučilišta u Osijeku za razdoblje 2014.-2016.

<p><b>Copyright information:</b></p><p>Taken from "The SUMO E3 ligase, , regulates flowering by controlling a salicylic acid-mediated floral promotion pathway and through affects on chromatin structure"</p><p></p><p>The Plant Journal 2008;53(3):530-540.</p><p>Published online Jan 2008</p><p>PMCID:PMC2254019.</p><p>© 2007 The Authors Journal compilation 2007 Blackwell Publishing Ltd</p

sj-docx-1-nms-10.1177_14614448231163228 – Supplemental material for User agency–based versus machine agency–based misinformation interventions: The effects of commenting and AI fact-checking labeling on attitudes toward the COVID-19 vaccination

Supplemental material, sj-docx-1-nms-10.1177_14614448231163228 for User agency–based versus machine agency–based misinformation interventions: The effects of commenting and AI fact-checking labeling on attitudes toward the COVID-19 vaccination by Jiyoung Lee and Kim Bissell in New Media & Society</p

Isobenzofuranone- and Chromone-Based Blue Delayed Fluorescence Emitters with Low Efficiency Roll-Off in Organic Light-Emitting Diodes

Significant efforts have been devoted to the development of novel efficient blue-emitting molecules for organic light-emitting diode (OLED) applications. Blue organic emitters exhibiting thermally activated delayed fluorescence (TADF) have the potential to achieve ∼100% internal electroluminescence quantum efficiency in OLEDs. In this paper, we report a promising molecular design strategy for obtaining appropriate high singlet and triplet excited energies, short exciton lifetimes, and high quantum efficiencies in blue TADF emitters. We introduce isobenzofuranone and chromone containing a cyclic ketone or lactone moiety as effective acceptor building units to construct donor–acceptor TADF emitters. Owing to their small singlet–triplet energy splitting, properly contracted π-conjugation, and weakened intramolecular charge-transfer character, these new emitters display strong blue TADF emissions with high photoluminescence quantum yields (53–92%) and notably short TADF emission lifetimes (2.8–4.3 μs) in thin films. Blue TADF-OLEDs utilizing these emitters exhibit external electroluminescence quantum efficiencies of up to 16.2% and extremely low efficiency roll-off even at practical high luminance. The current findings open new avenues for designing practically usable high-performance blue TADF emitters with simple molecular structures

Effect of Atom Substitution in Chalcogenodiazole-Containing Thermally Activated Delayed Fluorescence Emitters on Radiationless Transition

Radiationless transition between the lowest singlet (S₁) and triplet (T₁) excited states in the thermally activated delayed fluorescence (TADF) were investigated with respect to molecular design. The photophysical, transient photoluminescence and electroluminescence (EL) characteristics of two chalcogenodiazole-containing TADF emitters were compared. These contained 1,3,4-oxadiazole or 1,3,4-thiadiazole. The effect of substituting oxygen with sulfur on TADF was caused by an electron-pair-accepting conjugative effect. This effect resulted from the vacant 3<i>d</i>-orbitals of divalent sulfur in the thiadiazole heteroring. Atom substitution narrowed the gap between the highest occupied and lowest unoccupied molecular orbital energy levels, and enhanced S₁ → T₁ intersystem crossing. These effects resulted from the enhanced acceptor strength and orbital angular momentum by the vacant 3<i>d</i>-orbitals of sulfur. Atom substitution increased the contribution of the delayed fluorescence component to the total EL efficiency (65.1% → 78.0%). This resulted from enhanced reverse intersystem crossing, because of the reduced energy gap between S₁ and T₁

Dynamic Rearrangement of F-Actin Is Required to Maintain the Antitumor Effect of Trichostatin A

<div><p>Actin plays a role in various processes in eukaryotic cells, including cell growth and death. We investigated whether the antitumor effect of trichostatin A (TSA) is associated with the dynamic rearrangement of F-actin. TSA is an antitumor drug that induces hyper-acetylation of histones by inhibiting histone deacetylase. HeLa human cervical cancer cells were used to measure the antitumor effect of TSA. The percent cell survival was determined by an MTT assay. Hypodiploid cell formation was assessed by flow cytometry. Collapse of the mitochondrial membrane potential (MMP) was identified by a decrease in the percentage of cells with red MitoProbe J-aggregate (JC-1) fluorescence. Cell survival was reduced by treatment with TSA, as judged by an MTT assay and staining with propidium iodide, FITC-labeled annexin V, or 4′,6-diamidino-2-phenylindole (DAPI). TSA also induced an MMP collapse, as judged by the measurement of intracellular red JC-1 fluorescence. In addition, the F-actin depolymerizers cytochalasin D (CytoD) and latrunculin B (LatB) induced an MMP collapse and increased apoptotic cell death in HeLa cells. However, our data show that apoptotic cell death and the MMP collapse induced by TSA were decreased by the co-treatment of cells with CytoD and LatB. These findings demonstrate that the dynamic rearrangement of F-actin might be necessary for TSA-induced HeLa cell apoptosis involving a TSA-induced MMP collapse. They also suggest that actin cytoskeleton dynamics play an important role in maintaining the therapeutic effects of antitumor agents in tumor cells. They further suggest that maintaining the MMP could be a novel strategy for increasing drug sensitivity in TSA-treated tumors.</p></div

TSA-mediated cell death in HeLa cells was inhibited by co-treatment with CytoD or LatB.

<p>Hypodiploid cell formation was increased by incubation with TSA, CytoD, or LatB. <b>A–C:</b> HeLa cells were treated with various concentrations of TSA (A), CytoD (B), or LatB (C) for 48 h. <b>D:</b> HeLa cells were treated for 36 h with various doses of TSA (•) in the presence (○) or absence of CytoD (upper) or LatB (lower). Cell density was measured by an MTT assay, as described in the Materials and Methods. The data in the line graph represent the mean ± SEM. *<i>p</i><0.05, **<i>p</i><0.01 vs. non-TSA-treated and non-CytoD- or non-LatB-treated control cells (A<b>–</b>E). ^#<i>p</i><0.05, ^##<i>p</i><0.01 vs. TSA-treated and non-CytoD-treated (D) or non-LatB-treated (E) control cells.</p

The MMP was decreased by incubation with CytoD or LatB.

<p><b>A–B:</b> HeLa cells were treated with 1,000(A) or 500 nM LatB (B) for an appropriate length of time. Cells were detached by incubation with trypsin/EDTA and collected at each time point. A total of 1×10⁶ cells suspended in PBS were incubated with 2.5 µg/ml JC-1 for 10 min at 37°C. Stained cells were washed with PBS twice and analyzed immediately with a NucleoCounter NC-3000 cytometer (ChemoMetec). An MMP collapse was detected as a decrease in the percentage of cells with high red fluorescence intensity. The data in the bar graph represent the mean ± SEM. *<i>p</i><0.05, **<i>p</i><0.01 vs. non-CytoD-treated control cells; ^#<i>p</i><0.05 vs. non-LatB-treated control cells.</p

MOESM1 of A hybrid framework combining background subtraction and deep neural networks for rapid person detection

Additional file 1. Annotated image examples per class

Enhancement of Photoinduced Electron Transfer in Self-Assembled Polymer Films Using Mixed Metal–Terpyridine Complexes

The design and synthesis of photoactive polymeric systems are important in regard to solar energy harvesting and utilization. In this report, we synthesized photoactive polymeric thin films via iterative self-assembly using reversible metal–terpyridine (M–tpy) interactions. The growth rate of thin film deposition depends on the metal ion of choice. Ru­(II)­(tpy)₂-incorporated poly­(vinyl alcohol) also functionalized with tpy was subjected to iterative self-assembly on glass substrates. UV–vis spectroscopy and surface profilometer investigations show that the polymeric thin films with Cu­(II) grew 2 times faster than those with Zn­(II), attributed to the strong M–tpy interaction. Interestingly, photocurrent generated in the polymeric thin films with Zn­(II) was much higher than those of other films. The apparent diffusion rate constant (<i>k</i>_app) was measured for the electron hopping process via potential-step chronoamperometry. As a result, the <i>k</i>_app for the polymeric thin films with Zn­(II) was almost 2 times larger than those with other metal ions. The choice of metal ions appears crucial in the mixed metal–tpy complex systems not only for the film growth but also for the efficient photoinduced electron transfer

Hypodiploid cell formation in HeLa cells was inhibited by treatment with CytoD or LatB in the presence of TSA.

<p><b>A:</b> HeLa cells were treated with various concentrations of TSA for 12, 24, or 48<b>B:</b> HeLa cells were treated with 1,000 nM CytoD for 6, 12, or 18 h. <b>C:</b> HeLa cells were treated with 500 nM LatB for 3, 6, or 12 h. <b>D:</b> HeLa cells were treated for 24 h with various concentrations of TSA in the presence or absence of 500 nM LatB or 1,000 nM CytoD. Cells were fixed with 40% ethanol and stained with PI, and then hypodiploid cells were analyzed by flow cytometry. <b>E–F:</b> HeLa cells were treated for 16 h with 1,000 nM TSA in the presence or absence of 500 nM LatB or 1,000 nM CytoD. Cells were stained with annexin V-FITC and PI, and then analyzed by flow cytometry (E). Cells were fixed with 3% paraformaldehyde and stained with DAPI, and then observed under a fluorescence microscope at 400× magnification. Arrows indicate representative cells with chromosome condensation in each group (F, left). The data in the bar graph represent the mean ± SEM. **<i>p</i><0.01 vs. untreated control cells; ^#<i>p</i><0.05 vs. TSA-treated and non-CytoD-treated control cells; ^$<i>p</i><0.05 vs. TSA-treated and non-LatB-treated control cells (F, right).</p