Additional file 1: of Biological age as a useful index to predict seventeen-year survival and mortality in Koreans

Table S1. Inclusion criteria of cause of death for the study. Table S2. Overall distribution of biomarkers. Table S3. Number of deceased subjects according to cause of death and gender. Table S4. Influence of age difference (AgeDiff) on the mortality. Table S5. Hazard ratios for men according to chronological age subgroups and cause of death. Table S6. Hazard ratios for women according to chronological age subgroups and cause of death. Table S7. Hazard ratios for three age difference subgroups (AgeDiff) according to chronological age subgroups and gender when the event was death by cancer and non-cancerous disease. Figure S1. Distributions of percentage of deceased subjects according to gender, age difference (AgeDiff), and cause of death. Figure S2. Kaplan-Meier survival plots when the event was death by cancer or non-cancer disease. Figure S3. Kaplan-Meier survival plots when the event was death by cancer + non-cancer disease. Figure S4. Kaplan-Meier survival plots when the event was death by cancer. Figure S5. Kaplan-Meier survival plots when the event was death by non-cancer disease. (DOCX 678 kb

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-7

Nberg Equilibrium test are shown in the table. Triggering tabs for Data Import, Haplotype Estimation, LD Blocking and Case-Control Study are shown on the left panel.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

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<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-6

D by SNPAnalyzer 2.0, and (C) African American ethnic group and (D) Asian American ethnic group by Haploview program. The structures of LD blocks consisting of 100 SNPs are produced by (E) SNPAnalyzer 2.0 and by (F) Haploview program.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-5

Sis, (B) false discovery rate, (C) reconstructed haplotypes.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-0

Nberg Equilibrium test are shown in the table. Triggering tabs for Data Import, Haplotype Estimation, LD Blocking and Case-Control Study are shown on the left panel.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-4

Separately shown in the bar charts. P-values are log transformed and sorted by descending order. Odds ratios (OR) and 95% confidence interval of odds ratios are displayed simultaneously with p-value of the chi-square test in the upper table. Green horizontal line represents significance level.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis-1

PL-EM algorithm. The upper panel shows the control options for PL-EM algorithm. Middle panel shows the observed alleles and allele frequencies. The histogram and tables in the bottom panel shows the most likely haplotypes and their frequencies in a given sample. Individual haplotypes and estimation accuracies are shown on the right part of the bottom panel.<p><b>Copyright information:</b></p><p>Taken from "SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis"</p><p>http://www.biomedcentral.com/1471-2105/9/290</p><p>BMC Bioinformatics 2008;9():290-290.</p><p>Published online 23 Jun 2008</p><p>PMCID:PMC2453143.</p><p></p