Additional file 2: Figure S2. of M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway

Levels of the p-ERK, p-Ikkα/β, total STAT3, ERK, Ikkα, and Ikkβ proteins were detected using western blotting. (A) Levels of the p-STAT3 and STAT3 proteins in the control, LPS, and M2-CM + LPS groups. (B) Levels of the p-ERK and ERK proteins in the control, M2-CM + LPS, and M2-CM groups. (C) Levels of the p-Ikkα/β, Ikkα, and Ikkβ proteins in the control, M2-CM + LPS, and M2-CM groups. (TIFF 601 kb

MOESM1 of Effects of mesenchymal stem cells on solid tumor metastasis in experimental cancer models: a systematic review and meta-analysis

Additional file 1: Table S1. The detail characteristics of all the publications included

MOESM2 of Effects of mesenchymal stem cells on solid tumor metastasis in experimental cancer models: a systematic review and meta-analysis

Additional file 2: Figure S1. MSCs with promoting effects on tumor metastasis

Additional file 3: Table S2. of ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway

bHLH transcription factors that could possibly bind G6PD promoter by using bioinformatic analysis. (DOCX 30 kb

Additional file 1: Figure S1. of ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway

IC50 evaluation on HCC oxaliplatin resistant cells and their parental cells. Dose-response curves between the oxaliplatin concentration and the percentage of cell activity were plotted. The data represent the mean value ± standard deviation of three independent experiments performed in triplicate. The IC50 value was 10.3 ± 0.75 for 97H vs. 1.32 ± 0.03 uM for 97H–OXA (P < 0.001). The IC50 value was 11.72 ± 0.83 uM for Hep3B vs. 1.31 ± 0.25 uM for 3B–OXA (P < 0.001). (PDF 606 kb

Additional file 4: Figure S2. of ID1 promotes hepatocellular carcinoma proliferation and confers chemoresistance to oxaliplatin by activating pentose phosphate pathway

ID1/G6PD signaling predicts unfavourable clinical prognosis in HCC patients. Differences in overall survival according to the expression of ID1 (A), G6PD (B) and their combination (C) were found to be statistically significant in HCC TCGA database. (PDF 1126 kb