The Pathology of the Feline Model of Mucopolysaccharidosis VI

Three cats with feline arylsulfatase-B-deficient mucopolysaccharidosis were studied by light and transmission electron microscopy. Membrane-bound cytoplasmic inclusions were present in hepatocytes, bone marrow granulocytes, vascular smooth muscle cells, and fibroblasts in skin, cornea, and cardiac valves. Central nervous system lesions were restricted to mild ventricular dilatation, perithelial cell vacuolation, and, in one animal, cord compression by vertebral exostoses. The lesions in these cats closely resembled those described in human patients with mucopolysaccharidosis VI (Maroteaux-Lamy syndrome)

Fatty acid relationship in an aquatic food chain

The relationships amongst the fatty acids of the lipids from members of a model aquatic food chain were examined. The basic pattern of the fatty acids in the members, algae‐brine shrimp‐hydra, originated in the phytoplankton. Fatty acids in the neutral lipids of adult brine shrimp,Artemia salina, closely resembled dietary, or algal, fatty acids, whereas the phospholipid acids differed considerably from those in the algae. Fatty acids from the total lipids ofHydra pseudoligactis fed brine shimp nauplii also resembled the dietary acids, but more C20 polyunsaturates and fewer C18 unsaturated acids were present in those raised at 10C than were found at 20C.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141771/1/lipd0427.pd