Cell migration directionality and speed are independently regulated by RasG and Gβ in Dictyostelium cells in electrotaxis.

Motile cells manifest increased migration speed and directionality in gradients of stimuli, including chemoattractants, electrical potential and substratum stiffness. Here, we demonstrate that Dictyostelium cells move directionally in response to an electric field (EF) with specific acceleration/deceleration kinetics of directionality and migration speed. Detailed analyses of the migration kinetics suggest that migration speed and directionality are separately regulated by Gβ and RasG, respectively, in EF-directed cell migration. Cells lacking Gβ, which is essential for all chemotactic responses in Dictyostelium, showed EF-directed cell migration with the same increase in directionality in an EF as wild-type cells. However, these cells failed to show induction of the migration speed upon EF stimulation as much as wild-type cells. Loss of RasG, a key regulator of chemoattractant-directed cell migration, resulted in almost complete loss of directionality, but similar acceleration/deceleration kinetics of migration speed as wild-type cells. These results indicate that Gβ and RasG are required for the induction of migration speed and directionality, respectively, in response to an EF, suggesting separation of migration speed and directionality even with intact feedback loops between mechanical and signaling networks

Nucleus-Nucleus Bremsstrahlung from Ultrarelativistic Collisions

The bremsstrahlung produced when heavy nuclei collide is estimated for central collisions at the Relativistic Heavy Ion Collider. Soft photons can be used to infer the rapidity distribution of the outgoing charge. An experimental design is outlined.Comment: 12 pages, 7 figures, uses revte

Cd3As2 is Centrosymmetric

This is a revised version of a manuscript that was originally posted here in February of 2014. It has been accepted at the journal Inorganic Chemistry after reviews that included those of two crystallographers who made sure all the t's were crossed and the i's were dotted. The old work (from 1968) that said that Cd3As2 was noncentrosymmetric was mistaken, with the authors of that study making a type of error that in the 1980s became infamous in crystallography. As a result of the increased scrutiny of the issue of centrosymmetricity of the 1980's, there are now much better analysis tools to resolve the issue fully, and its important to understand that not just our crystals are centrosymmetric, even the old guy's crystals were centrosymmetric (and by implication everyone's are). There is no shame in having made that error back in the day and those authors would not find the current centrosymmetric result controversial; their paper is excellent in all other aspects. This manuscript describes how the structure is determined, explains the structure schematically, calculates the electronic structure based on the correct centrosymmetric crystal structure, and gives the structural details that should be used for future analysis and modeling.Comment: Accepted by ACS Inorganic Chemistr

Quantum and frustration effects on fluctuations of the inverse compressibility in two-dimensional Coulomb glasses

We consider interacting electrons in a two-dimensional quantum Coulomb glass and investigate by means of the Hartree-Fock approximation the combined effects of the electron-electron interaction and the transverse magnetic field on fluctuations of the inverse compressibility. Preceding systematic study of the system in the absence of the magnetic field identifies the source of the fluctuations, interplay of disorder and interaction, and effects of hopping. Revealed in sufficiently clean samples with strong interactions is an unusual right-biased distribution of the inverse compressibility, which is neither of the Gaussian nor of the Wigner-Dyson type. While in most cases weak magnetic fields tend to suppress fluctuations, in relatively clean samples with weak interactions fluctuations are found to grow with the magnetic field. This is attributed to the localization properties of the electron states, which may be measured by the participation ratio and the inverse participation number. It is also observed that at the frustration where the Fermi level is degenerate, localization or modulation of electrons is enhanced, raising fluctuations. Strong frustration in general suppresses effects of the interaction on the inverse compressibility and on the configuration of electrons.Comment: 15 pages, 18 figures, To appear in Phys. Rev.

A framework for evaluating automatic image annotation algorithms

Several Automatic Image Annotation (AIA) algorithms have been introduced recently, which have been found to outperform previous models. However, each one of them has been evaluated using either different descriptors, collections or parts of collections, or "easy" settings. This fact renders their results non-comparable, while we show that collection-specific properties are responsible for the high reported performance measures, and not the actual models. In this paper we introduce a framework for the evaluation of image annotation models, which we use to evaluate two state-of-the-art AIA algorithms. Our findings reveal that a simple Support Vector Machine (SVM) approach using Global MPEG-7 Features outperforms state-of-the-art AIA models across several collection settings. It seems that these models heavily depend on the set of features and the data used, while it is easy to exploit collection-specific properties, such as tag popularity especially in the commonly used Corel 5K dataset and still achieve good performance

Radiative and Collisional Energy Loss, and Photon-Tagged Jets at RHIC

The suppression of single jets at high transverse momenta in a quark-gluon plasma is studied at RHIC energies, and the additional information provided by a photon tag is included. The energy loss of hard jets traversing through the medium is evaluated in the AMY formalism, by consistently taking into account the contributions from radiative events and from elastic collisions at leading order in the coupling. The strongly-interacting medium in these collisions is modelled with (3+1)-dimensional ideal relativistic hydrodynamics. Putting these ingredients together with a complete set of photon-production processes, we present a calculation of the nuclear modification of single jets and photon-tagged jets at RHIC.Comment: 4 pages, 4 figures, contributed to the 3rd International Conference on Hard and Electro-Magnetic Probes of High-Energy Nuclear Collisions (Hard Probes 2008), typos corrected, published versio

Shear viscosity in ϕ4\phi^4 theory from an extended ladder resummation

We study shear viscosity in weakly coupled hot $\phi^4$ theory using the CTP formalism . We show that the viscosity can be obtained as the integral of a three-point function. Non-perturbative corrections to the bare one-loop result can be obtained by solving a decoupled Schwinger-Dyson type integral equation for this vertex. This integral equation represents the resummation of an infinite series of ladder diagrams which contribute to the leading order result. It can be shown that this integral equation has exactly the same form as the Boltzmann equation. We show that the integral equation for the viscosity can be reexpressed by writing the vertex as a combination of polarization tensors. An expression for this polarization tensor can be obtained by solving another Schwinger-Dyson type integral equation. This procedure results in an expression for the viscosity that represents a non-perturbative resummation of contributions to the viscosity which includes certain non-ladder graphs, as well as the usual ladders. We discuss the motivation for this resummation. We show that these resummations can also be obtained by writing the viscosity as an integral equation involving a single four-point function. Finally, we show that when the viscosity is expressed in terms of a four-point function, it is possible to further extend the set of graphs included in the resummation by treating vertex and propagator corrections self-consistently. We discuss the significance of such a self-consistent resummation and show that the integral equation contains cancellations between vertex and propagator corrections.Comment: Revtex 40 pages with 29 figures, version to appear in Phys. Rev.