Social intuition: behavioral and neurobiological considerations

Social intuition is instrumental in bringing about successful human interactions, yet its behavioral and neural underpinnings are still poorly understood. We focus in this article on the automatic, involuntary, nature of social intuition, rather than on higher-level cognitive and explicit Theory-of-Mind processes (which contribute to rendering social intuition meaningful in real-life situations). We argue that social-affective implicit learning plays a crucial role in establishing automatic social intuition. These implicit learning processes involve associations between the perception of other’s bodily articulations, concurrent events, and the consequences or outcomes in terms of subsequent actions, affective valences and visceral states. The traditional non-social implicit learning paradigms do not allow one to draw conclusions about the role of implicit learning processes in social intuition, as they lack these vital characteristics typically associated with human actions. We introduce a new implicit learning paradigm, which aims to fill these gaps. It targets agile, rapid, social-affective learning processes, involving cue contingencies with a relatively simple structure, unlike the very complex structures that underpin the traditional tasks. The paradigm features matching social and non-social versions, allowing direct comparison. Preliminary data suggest equal performance of TD (typically-developed) and ASC (autism spectrum conditions) groups on the non-social version, but impaired implicit learning in ASC on the social version. We hypothesize that this reflects an anomalous use of implicitly learned affective information in ASC when judging other people. We further argue that the mirror neuron mechanism (MNM), which is part of the Action Observation Network, forms an integral part of the neural substrate for social intuition. In particular as there are indications that the MNM supports action anticipation, and that implicitly learned information can trigger MNM activation, which both seem vital to a social intuition ability. The insights that can be derived from comparing the performances of TD and ASC individuals on (non)social implicit learning tasks, and the implications for the role of MNM activation, are discussed

The Role of Pattern Extrapolation in the Perception of Dynamic Facial Expressions in Autism Spectrum Disorder

Changes in the intensity and type of facial expressions reflect alterations in the emotional state of the agent. Such “direct” access to the other’s affective state might, top-down, influence the perception of the facial expressions that gave rise to the affective state inference. Previously, we described a perceptual bias occurring when the last, neutral, expression of offsets of facial expressions (joy-to-neutral and anger-to-neutral), was evaluated. Individuals with high-functioning autism (HFA) and matched typically developed (TD) individuals rated the neutral expression at the end of the joy-offset videos as slightly angry and the identical neutral expression at the end of the anger-offset videos as slightly happy (“overshoot” bias). That study suggested that the perceptual overshoot response bias in the TD group could be best explained by top-down “emotional anticipation,” i.e., the involuntary/automatic anticipation of the agent’s next emotional state of mind, generated by the immediately preceding perceptual history (low-level mind reading). The experimental manipulations further indicated that in the HFA group the “overshoot” was better explained by contrast effects between the first and last facial expressions, both presented for a relatively long period of 400 ms. However, in principle, there is another, more parsimonious, explanation, which is pattern extrapolation or representational momentum (RM): the extrapolation of a pattern present in the dynamic sequence. This hypothesis is tested in the current study, in which 18 individuals with HFA and a matched control group took part. In a base-line condition, joy-offset and anger-offset video-clips were presented. In the new experimental condition, the clips were modified so as to create an offset-onset-offset pattern within each sequence (joy-to-anger-to-neutral and anger-to-joy-to-neutral). The final neutral expressions had to be evaluated. The overshoot bias was confirmed in the base-line condition for both TD and HFA groups, while the experimental manipulation removed the bias in both groups. This outcome ruled out pattern extrapolation or RM as explanation for the perceptual “overshoot” bias in the HFA group and suggested a role for facial contrast effects in HFA. This is compatible with the view that ASD individuals tend to lack the spontaneous “tracking” of changes in the others’ affective state and hence show no or reduced emotional anticipation

Atypical emotional anticipation in high-functioning autism

"Background: Understanding and anticipating others’ mental or emotional states relies on the processing of social cues, such as dynamic facial expressions. Individuals with high-functioning autism (HFA) may process these cues differently from individuals with typical development (TD) and purportedly use a ‘mechanistic’ rather than a ‘mentalistic’ approach, involving rule- and contingency-based interpretations of the stimuli. The study primarily aimed at examining whether the judgments of facial expressions made by individuals with TD and HFA would be similarly affected by the immediately preceding dynamic perceptual history of that face. A second aim was to explore possible differences in the mechanisms underpinning the perceptual judgments in the two groups. Methods: Twenty-two adults with HFA and with TD, matched for age, gender and IQ, were tested in three experiments in which dynamic, ‘ecologically valid’ offsets of happy and angry facial expressions were presented. Participants evaluated the expression depicted in the last frame of the video clip by using a 5-point scale ranging from slightly angry via neutral to slightly happy. Specific experimental manipulations prior to the final facial expression of the video clip allowed examining contributions of bottom-up mechanisms (sequential contrast/ context effects and representational momentum) and a top-down mechanism (emotional anticipation) to distortions in the perception of the final expression. Results: In experiment 1, the two groups showed a very similar perceptual bias for the final expression of joy-to-neutral and anger-to-neutral videos (overshoot bias). In experiment 2, a change in the actor’s identity during the clip removed the bias in the TD group, but not in the HFA group. In experiment 3, neutral-to-joy/anger-to-neutral sequences generated an undershoot bias (opposite to the overshoot) in the TD group, whereas no bias was observed in the HFA group. Conclusions: We argue that in TD individuals the perceptual judgments of other’s facial expressions were underpinned by an automatic emotional anticipation mechanism. In contrast, HFA individuals were primarily influenced by visual features, most notably the contrast between the start and end expressions, or pattern extrapolation. We critically discuss the proposition that automatic emotional anticipation may be induced by motor simulation of the perceived dynamic facial expressions and discuss its implications for autism.

Full characterization and analysis of a terahertz heterodyne receiver based on a NbN hot electron bolometer

We present a complete experimental characterization of a quasioptical twin-slot antenna coupled small area (1.0×0.15 µm^2) NbN hot electron bolometer (HEB) mixer compatible with currently available solid state tunable local oscillator (LO) sources. The required LO power absorbed in the HEB is analyzed in detail and equals only 25 nW. Due to the small HEB volume and wide antenna bandwidth, an unwanted direct detection effect is observed which decreases the apparent sensitivity. Correcting for this effect results in a receiver noise temperature of 700 K at 1.46 THz. The intermediate frequency (IF) gain bandwidth is 2.3 GHz and the IF noise bandwidth is 4 GHz. The single channel receiver stability is limited to 0.2–0.3 s in a 50 MHz bandwidth

Experimental Verification of Electromagnetic Simulations of a HIFI Mixer Sub-Assembly

Phase II of the study "Far-Infrared Optics Design & Verification", commissioned by the European Space Agency (ESA), we investigate the ability of several commercial software packages (GRASP, CODEV, GLAD and ASAP) to predict the performance of a representative example of a submillimeter-wave optical system. In this paper, we use the software packages to predict the behaviour of a Mixer Sub-Assembly (MSA) of HIFI, and we compare the simulations with near-field measurements at 480 GHz. In order to be able to distinguish between the predictions of the packages, we move the corrugated horn of the MSA through its nominal focus position. A unique feature of the experimental arrangement is that the measured position of every field point is known absolutely to within fractions of a wavelength. In this paper we present the results of this through-focus experiment, which give a good first-order indication of the agreement between measured and simulated behaviour of a typical submillimeter-wave optical system

Value of prominent flow voids without cord edema in the detection of spinal arteriovenous fistulae

Purpose: To determine the prevalence of spinal dural arteriovenous fistulae (SDAVF) in patients presenting with prominent vascular flow voids on imaging without other imaging findings suggestive of SDAVF. Methods: We retrospectively identified patients from January 1, 2005 to March 1, 2012 who underwent spinal angiography for suspected SDAVF with prominent vascular flow voids on prior imaging. We excluded patients with other major spinal pathology or other imaging findings of SDAVF including cord hyperintensity, enhancement, or expansion. We calculated the proportion of patients with positive findings for SDAVF on angiography and evaluated the prevalence of SDAVF for this finding alone and in correlation with clinical findings. Results: 18 patients underwent spinal angiography for prominent flow voids on imaging without other spinal pathology or imaging findings of SDAVF. Three had a SDAVF detected on angiography. The prevalence of SDAVF in this population was low, only 17% (95% CI 6-39%). All of the patients with positive angiography findings had myelopathy, increasing the prevalence to 100% if the additional clinical finding of myelopathy was present. Conclusions: Prominent flow voids without other imaging findings suggestive of SDAVF is poorly predictive of the presence of a SDAVF, unless myelopathy is present clinically. © 2014 Alhilali et al