6 research outputs found
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations
Polycationic Ligands in Gold Catalysis: Synthesis and Applications of Extremely π‑Acidic Catalysts
Very
often ligands are anionic or neutral species. Cationic ones
are rare, and, when used, the positively charged groups are normally
appended to the periphery of the ligand. Here, we describe a dicationic
phosphine with no spacer between the phosphorus atom and the two positively
charged groups. This structural feature makes its donor ability poorer
than that of phosphites and only comparable to extremely toxic or
pyrophoric compounds such as PF<sub>3</sub> or PÂ(CF<sub>3</sub>)<sub>3</sub>. By exploiting these properties, a new Au catalyst has been
developed displaying a dramatically enhanced capacity to activate
Ï€-systems. This has been used to synthesize very sterically
hindered and naturally occurring 4,5-disubstituted phenanthrenes.
The present approach is expected to be applicable to the development
and improvement of many other transition metal catalyzed transformations
that benefit from extremely strong π-acceptor ligands. The mechanism
of selected catalytic transformations has been explored by density
functional calculations