Effect of IL-6 inhibition on body weight and adipokine serum levels in human subjects.

<p>Data are expressed as Means ± SEM. * = p<0.05.</p

Effect of IL-6 inhibition on lipoprotein (a) levels in human subjects.

<p>Data are expressed as Means ± SEM of lipoprotein (a) levels x-fold compared to time point 0 month. * = p<0.05.</p

Metabolic parameters of the study population.

<p>TG =  triglycerides, LDL =  LDL-cholesterol, HDL =  HDL-cholesterol, HbA1c =  glycosylated haemoglobin A1c levels.</p>(a)<p> =  p<0.05 compared to 0 month,</p>(b)<p> =  p<0.05 compared to 0 month. Means ± SEM.</p

Demographic, anthropometric and clinical characteristics of the study population.

<p>BMI  =  body mass index, f =  female, m =  male. Means ± SEM.</p

Effect of IL-6 inhibition on insulin sensitivity of human subject.

<p>Data are expressed as Means ± SEM. * = p<0.05.</p

Correlation between changes of CRP levels with changes of markers of insulin resistance during the study period.

<p>Spearman Correlation analysis, <i>p</i> =  correlation coefficient, P =  significances level.</p

Effect of IL-6 inhibition on inflammatory parameters in human subjects.

<p>Data are expressed as Means ± SEM. * = p<0.05.</p