MOESM1 of Knowledge, attitudes and perceptions of stroke: a cross-sectional survey in rural and urban Uganda

Additional file 1. The study questionnaire

Additional file 2: Table S2. of Determinants of hypertension in a young adult Ugandan population in epidemiological transition—the MEPI-CVD survey

Factors associated with hypertension among adults (age 18–40 years) in Wakiso district, Central Uganda. (PDF 175 kb

Additional file 1: Table S1. of Determinants of hypertension in a young adult Ugandan population in epidemiological transition—the MEPI-CVD survey

Additional baseline characteristics of the survey population in Wakiso district, Central Uganda. (PDF 153 kb

Characteristics of HIV infected adults attending two large ambulatory HIV clinics in Uganda.

<p>CIMT: Carotid Intima Media Thickness, IQR: Inter quartile range, WHO: World Health Organization, ART: Anti-Retroviral Therapy, NSAID: Non-Steroid Anti Inflammatory Drugs e.g. Ibuprofen, HDL: High Density Lipoprotein, LDL: Low Density Lipoprotein, TC-HDL: Total Cholesterol- High Density Lipoprotein ratio, hsCRP: high sensitivity C-reactive protein, ESR: Erythrocyte sedimentation rate</p><p>*Three patients were taking Dapsone as prophylaxis for opportunistic infections</p

Effect of a 72 Hour Stroke Care Bundle on Early Outcomes after Acute Stroke: A Non Randomised Controlled Study

<div><p>Background</p><p>Integrated care pathways (ICP) in stroke management are increasingly being implemented to improve outcomes of acute stroke patients. We evaluated the effect of implementing a 72 hour stroke care bundle on early outcomes among patients admitted within seven days post stroke to the national referral hospital in Uganda.</p><p>Methods</p><p>In a one year non-randomised controlled study, 127 stroke patients who had ‘usual care’ (control group) were compared to 127 stroke patients who received selected elements from an ICP (intervention group). Patients were consecutively enrolled (controls first, intervention group second) into each group over 5 month periods and followed to 30-days post stroke. Incidence outcomes (mortality and functional ability) were compared using chi square test and adjusted for potential confounders. Kaplan Meier survival estimates and log rank test for comparison were used for time to death analysis for all strokes and by stroke severity categories. Secondary outcomes were in-hospital mortality, median survival time and median length of hospital stay.</p><p>Results</p><p>Mortality within 7 days was higher in the intervention group compared to controls (RR 13.1, 95% CI 3.3–52.9). There was no difference in 30-day mortality between the two groups (RR 1.2, 95% CI 0.5–2.6). There was better 30-day survival in patients with severe stroke in the intervention group compared to controls (P = 0.018). The median survival time was 30 days (IQR 29–30 days) in the control group and 30 days (IQR 7–30 days) in the intervention group. In the intervention group, 41patients (32.3%) died in hospital compared to 23 (18.1%) in controls (P < 0.001). The median length of hospital stay was 8 days (IQR 5–12 days) in the controls and 4 days (IQR 2–7 days) in the intervention group. There was no difference in functional outcomes between the groups (RR 0.9, 95% CI 0.4–2.2).</p><p>Conclusions</p><p>While implementing elements of a stroke-focused ICP in a Ugandan national referral hospital appeared to have little overall benefit in mortality and functioning, patients with severe stroke may benefit on selected outcomes. More research is needed to better understand how and when stroke protocols should be implemented in sub-Saharan African settings.</p><p>Trial Registration</p><p>Pan African Clinical Trials Registry <a href="http://www.pactr.org/ATMWeb/appmanager/atm/atmregistry?_nfpb=true&_windowLabel=BasicSearchUpdateController_1&BasicSearchUpdateController_1_actionOverride=%2Fpageflows%2Ftrial%2FbasicSearchUpdate%2FviewTrail&BasicSearchUpdateController_1id=1272" target="_blank">PACTR201510001272347</a></p></div

Logistic regression for factors associated with subclinical atherosclerosis among HIV infected adults attending two large ambulatory HIV clinics in Uganda.

<p>CIMT: Carotid Intima Media Thickness, HDL: High Density Lipoprotein, LDL: Low Density Lipoprotein, TC-HDL: Total Cholesterol- High Density Lipoprotein ratio, hsCRP: high sensitivity C - reactive protein, ESR: Erythrocyte sedimentation rate, ART: Antiretroviral therapy.</p

The distribution of subclinical atherosclerosis across the Framingham risk score categories (n = 181).

<p>Note: 5 of the participants had missing variables for FRS score hence not included.</p><p>CIMT: Carotid intima media thickness, CI: Confidence interval</p

Burden, predictors and short-term outcomes of peripartum cardiomyopathy in a black African cohort

Peripartum cardiomyopathy (PPCM) is an idiopathic cardiomyopathy presenting with acute heart failure during the peripartum period. It is common in patients of African ancestry. Currently, there is paucity of data on the burden, predictors and outcomes of PPCM in Uganda. This study aimed to investigate the prevalence, predictors and six-month outcomes of PPCM in an adult cohort attending a tertiary specialised cardiology centre in Kampala, Ugand

Spearman correlation coefficients of hsCRP concentrations with CIMT and traditional cardiovascular risk factors among HIV infected adults.

<p>CIMT: Carotid Intima Media Thickness, HDL: High Density Lipoprotein, LDL: Low Density Lipoprotein, TC-HDL: Total Cholesterol- High Density Lipoprotein ratio, hsCRP: high sensitivity C - reactive protein.</p

Flow diagram showing HIV-infected adults that participated in the study.

<p>* 36 patients with confirmed active disease and 3 patients receiving steroid therapy were excluded. ART: Anti retroviral therapy, CIMT: Carotid intimal medial thickness, CBC: Complete blood count, ESR: Erythrocyte sedimentation rate, hsCRP: high sensitivity C-reactive protein.</p