Flowchart of Studies Identification and Selection Procedure.

<p>Flowchart of Studies Identification and Selection Procedure.</p

General Characteristics of the Studies.

<p>General Characteristics of the Studies.</p

Study Variables Conceptualization and Operationalization.

<p>Study Variables Conceptualization and Operationalization.</p

Summary Statistics for Random Effects Model of Pooled Effect Sizes.

<p><b>[Legend]</b>This is not a structural equation model. Diagram reflects the proposed paths in developmental regulation theory. Lines refer to proposed associations tested in the meta-analyses. Continuous line = significant association; Dashed line = non-significant association; <i>k</i> = number of studies testing the association; <i>r</i> = correlation coefficient; <i>I²</i> = I squared index. ***<i>p</i> <. 001.</p

Measures used to assess Goal blockage, Self-regulation and Wellbeing and its Reliability (when applicable).

<p>Measures used to assess Goal blockage, Self-regulation and Wellbeing and its Reliability (when applicable).</p

Additional file 1: of Influences on anticipated time to ovarian cancer symptom presentation in women at increased risk compared to population risk of ovarian cancer

Correlation matrix for variables in the structural equation models. Description of data: correlation matirx, means and standard deviations for variables in the three structural equation models. (DOCX 20 kb

Table_1_A systematic review of models of care for polycystic ovary syndrome highlights the gap in the literature, especially in developing countries.docx

IntroductionThe aim of the study was to identify available polycystic ovary syndrome (PCOS) models of care (MoCs) and describe their characteristics and alignment with the international PCOS guideline.MethodsOvid MEDLINE, All EBM, PsycINFO, Embase, and CINAHL were searched from inception until 11 July 2022. Any study with a description of a PCOS MoC was included. Non-evidence-based guidelines, abstracts, study protocols, and clinical trial registrations were excluded. We also excluded MoCs delivered in research settings to minimize care bias. Meta-analysis was not performed due to heterogeneity across MoCs. We describe and evaluate each MoC based on the recommendations made by the international evidence-based guideline for assessing and managing PCOS.ResultsOf 3,671 articles, six articles describing five MoCs were included in our systematic review. All MoCs described a multidisciplinary approach, including an endocrinologist, dietitian, gynecologist, psychologist, dermatologist, etc. Three MoCs described all aspects of PCOS care aligned with the international guideline recommendations. These include providing education on long-term risks, lifestyle interventions, screening and management of emotional well-being, cardiometabolic diseases, and the dermatological and reproductive elements of PCOS. Three MoCs evaluated patients’ and healthcare professionals’ satisfaction, with generally positive findings. Only one MoC explored the impact of their service on patients’ health outcomes and showed improvement in BMI.ConclusionThere is limited literature describing PCOS MoCs in routine practice. Future research should explore developing cost-effective co-created multidisciplinary PCOS MoCs globally. This may be facilitated by the exchange of best practices between institutions with an established MoC and those who are interested in setting one up.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=346539, identifier CRD42022346539.</p

Press release justifications, news uptake and justifications in news.

<p>(A) News uptake for press releases (PRs) with and without justifications for explicit advice. (B) News uptake for PRs with and without justifications for statements of relationship. (C) Association between justifications for explicit advice in the PR and justifications for explicit advice in resulting news articles. (D) Association between justifications for statements of relationship in the PR and justifications for statements of relationship in resulting news articles. All error bars are bootstrapped 95% confidence intervals.</p

Association between press release and news exaggeration.

<p>The proportions of news with exaggerated advice (A), or causal statements from correlational research (B) were higher when the associated press releases (PR) contained such exaggeration (N for Advice, PR = 247, news = 411; causal claims, PR = 164, news = 237). Error bars are 95% confidence intervals. See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168217#pone.0168217.t001" target="_blank">Table 1</a> for odds ratios. Partial results for non-human studies are in supporting information because low N meant this analysis could not be performed.</p

Press release caveats, news uptake and caveats in news.

<p>(A) News uptake for press releases (PRs) with and without caveats for explicit advice. (B) News uptake for PRs with and without caveats for causal claims. (C) Association between caveats for explicit advice in the PR and caveats for explicit advice in resulting news articles. (D) Association between caveats for causal claims in the PR and caveats for causal claims in resulting news articles. All error bars are bootstrapped 95% confidence intervals.</p