Additional file 1: Table S1. of The dog as a naturally-occurring model for insulin-like growth factor type 1 receptor-overexpressing breast cancer: an observational cohort study

Primary antibodies and immunohistochemical protocols (Benchmark XT Ventana, Roche Diagnostics). All dilutions were performed using a commercially available diluent (Ventana Medical Systems). aUltraview and bOptiview Universal DAB detection kit: multimer-technology based detection system. cIView Universal DAB detection kit: biotin streptavidin system. ERα: Estrogen Receptor alpha, PR: Progesterone Receptor, HER2: Epidermal Growth Factor type 2 Receptor, CK5/6: Cytokeratin 5/6, EGFR: Epidermal Growth Factor type 1 Receptor, IGF1R: Insulin-like growth factor type 1 receptor. CC1: Cell Conditioning 1. (DOC 33 kb

Additional file 2: Table S2. of The dog as a naturally-occurring model for insulin-like growth factor type 1 receptor-overexpressing breast cancer: an observational cohort study

Significant associations between IGF1R expression and clinicopathological features of 47 luminal canine mammary carcinomas. IGF1R score 0–1+ is considered as the reference for each parameter. IGF1R Insulin-like Growth Factor type 1 Receptor. LVI: Lymphovascular Invasion. OR: Odd Ratio. 95 % CI: 95 % Confidence Interval. (DOC 30 kb